Search Results - "Maciejewski, Benjamin S."

Interleukin-10 protects cultured fetal rat type II epithelial cells from injury induced by mechanical stretch by Lee, Hyeon-Soo, Wang, Yulian, Maciejewski, Benjamin S, Esho, Kenny, Fulton, Christiaan, Sharma, Surendra, Sanchez-Esteban, Juan

“…Mechanical ventilation plays a central role in the pathogenesis of bronchopulmonary dysplasia. However, the mechanisms by which excessive stretch of fetal or…”
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ROLES OF RhoA AND Rac1 ON ACTIN REMODELING AND CELL ALIGNMENT AND DIFFERENTIATION IN FETAL TYPE II EPITHELIAL CELLS EXPOSED TO CYCLIC MECHANICAL STRETCH by Silbert, Ophira, Wang, Yulian, Maciejewski, Benjamin S., Lee, Hyeon-Soo, Shaw, Sunil K., Sanchez-Esteban, Juan

“…Mechanical forces are critical for normal fetal lung development. However, the signaling events that promote lung maturation are not fully understood. In this…”
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771 A phase 1 study to assess safety, efficacy, pharmacokinetics, and pharmacodynamics of intratumoral CLN-617 (IL2/IL12 fusion protein) combined with pembrolizumab in patients with advanced solid tumors by Diab, Adi, El-Khoueiry, Anthony, Abdel-Wahab, Reham, Thomas, Sajeve, Hall, Evan, Wu, Kaida, Maciejewski, Benjamin S, Mehta, Naveen K, Liu, Laura, Michaelson, Jennifer S, Jones, Jeffrey A, Sweis, Randy

“…BackgroundThe use of pro-inflammatory cytokines as systemic therapies has been explored in the oncology field due to their ability to promote the function and…”
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Pharmacological inhibition to examine the role of DGAT1 in dietary lipid absorption in rodents and humans by Maciejewski, Benjamin S, LaPerle, Jennifer L, Chen, Danny, Ghosh, Avijit, Zavadoski, William J, McDonald, Thomas S, Manion, Tara B, Mather, Dawn, Patterson, Terrell A, Hanna, Maya, Watkins, Steven, Gibbs, E Michael, Calle, Roberto A, Steppan, Claire M

“…Alterations in fat metabolism, in particular elevated plasma concentrations of free fatty acids and triglycerides (TG), have been implicated in the…”
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Mechanical stretch promotes fetal type II epithelial cell differentiation via shedding of HB‐EGF and TGF‐α by Wang, Yulian, Maciejewski, Benjamin S., Soto‐Reyes, Dariana, Lee, Hyeon‐Soo, Warburton, David, Sanchez‐Esteban, Juan

“…The mechanisms by which mechanical forces promote fetal lung development are not fully understood. Here, we investigated differentiation of fetal type II…”
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A role for caveolin-1 in mechanotransduction of fetal type II epithelial cells by Wang, Yulian, Maciejewski, Benjamin S, Drouillard, Diana, Santos, Melissa, Hokenson, Michael A, Hawwa, Renda L, Huang, Zheping, Sanchez-Esteban, Juan

“…Mechanical forces are critical for fetal lung development. Using surfactant protein C (SP-C) as a marker, we previously showed that stretch-induced fetal type…”
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Pharmacological inhibition of diacylglycerol acyltransferase-1 and insights into postprandial gut peptide secretion by Maciejewski, Benjamin S, Manion, Tara B, Steppan, Claire M

“…AIM To examine the role that enzyme Acyl-CoA:diacylglycerol acyltransferase-1(DGAT1) plays in postprandial gut peptide secretion and signaling.METHODS The…”
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DNA microarray reveals novel genes induced by mechanical forces in fetal lung type II epithelial cells by YULIAN WANG, MACIEJEWSKI, Benjamin S, WEISSMANN, Gaia, SILBERT, Ophira, HAN, Hillary, SANCHEZ-ESTEBAN, Juan

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Strain-induced fetal type II epithelial cell differentiation is mediated via cAMP-PKA-dependent signaling pathway by Wang, Yulian, Maciejewski, Benjamin S, Lee, Nicole, Silbert, Ophira, McKnight, Nathan L, Frangos, John A, Sanchez-Esteban, Juan

“…The signaling pathways by which mechanical forces modulate fetal lung development remain largely unknown. In the present study, we tested the hypothesis that…”
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DNA microarray reveals novel genes induced by mechanical forces in fetal lung type II epithelial cells by Wang, Yulian, Maciejewski, Benjamin S, Weissmann, Gaia, Silbert, Ophira, Han, Hillary, Sanchez-Esteban, Juan

“…Mechanical forces are essential for normal fetal lung development. However, the cellular and molecular mechanisms regulating this process are still poorly…”
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Selective Activation of AMPK β 1-Containing Isoforms Improves Kidney Function in a Rat Model of Diabetic Nephropathy by Salatto, Christopher T, Miller, Russell A, Cameron, Kimberly O, Cokorinos, Emily, Reyes, Allan, Ward, Jessica, Calabrese, Matthew F, Kurumbail, Ravi G, Rajamohan, Francis, Kalgutkar, Amit S, Tess, David A, Shavnya, Andre, Genung, Nathan E, Edmonds, David J, Jatkar, Aditi, Maciejewski, Benjamin S, Amaro, Marina, Gandhok, Harmeet, Monetti, Mara, Cialdea, Katherine, Bollinger, Eliza, Kreeger, John M, Coskran, Timothy M, Opsahl, Alan C, Boucher, Germaine G, Birnbaum, Morris J, DaSilva-Jardine, Paul, Rolph, Tim

“…Diabetic nephropathy remains an area of high unmet medical need, with current therapies that slow down, but do not prevent, the progression of disease. A…”
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Mechanical stretch promotes fetal type II epithelial cell differentiation via shedding of HB-EGF and TGF-Î by Yulian Wang, Benjamin S. Maciejewski, Dariana Soto-Reyes, Hyeon-Soo Lee, David Warburton, Juan Sanchez-Esteban

“…The mechanisms by which mechanical forces promote fetal lung development are not fully understood. Here, we investigated differentiation of fetal type II…”
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Strain‐induced fetal type II epithelial cell differentiation is mediated via cAMP‐PKA‐dependent signaling pathway by Wang, Yulian, Maciejewski, Benjamin S., Lee, Nicole, Silbert, Ophira, Mcknight, Nathan L., Frangos, John A., Sanchez‐Esteban, Juan

“…The signaling pathways by which mechanical forces modulate fetal lung development remain largely unknown. In the present study, we tested the hypothesis that…”
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