Search Results - "Macias, Vanessa M."

Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi by Gantz, Valentino M, Jasinskiene, Nijole, Tatarenkova, Olga, Fazekas, Aniko, Macias, Vanessa M, Bier, Ethan, James, Anthony A

“…Genetic engineering technologies can be used both to create transgenic mosquitoes carrying antipathogen effector genes targeting human malaria parasites and to…”
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Targeted delivery of CRISPR-Cas9 ribonucleoprotein into arthropod ovaries for heritable germline gene editing by Chaverra-Rodriguez, Duverney, Macias, Vanessa M., Hughes, Grant L., Pujhari, Sujit, Suzuki, Yasutsugu, Peterson, David R., Kim, Donghun, McKeand, Sage, Rasgon, Jason L.

“…Cas9-mediated gene editing is a powerful tool for addressing research questions in arthropods. Current approaches rely upon delivering Cas9 ribonucleoprotein…”
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Cas9-Mediated Gene-Editing in the Malaria Mosquito Anopheles stephensi by ReMOT Control by Macias, Vanessa M, McKeand, Sage, Chaverra-Rodriguez, Duverney, Hughes, Grant L, Fazekas, Aniko, Pujhari, Sujit, Jasinskiene, Nijole, James, Anthony A, Rasgon, Jason L

“…Innovative tools are essential for advancing malaria control and depend on an understanding of molecular mechanisms governing transmission of malaria parasites…”
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Transposon and Transgene Tribulations in Mosquitoes: A Perspective of piRNA Proportions by Lau, Nelson C, Macias, Vanessa M

“…Mosquitoes, like , are dipterans, the order of "true flies" characterized by a single set of two wings. are prime model organisms for biomedical research,…”
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Heat shock protein 70 (Hsp70) mediates Zika virus entry, replication, and egress from host cells by Pujhari, Sujit, Brustolin, Marco, Macias, Vanessa M., Nissly, Ruth H., Nomura, Masashi, Kuchipudi, Suresh V., Rasgon, Jason L.

“…Zika virus (ZIKV) is a historically neglected mosquito-borne flavivirus that has caused recent epidemics in the western hemisphere. ZIKV has been associated…”
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Leaning Into the Bite: The piRNA Pathway as an Exemplar for the Genetic Engineering Need in Mosquitoes by Macias, Vanessa M, Palatini, Umberto, Bonizzoni, Mariangela, Rasgon, Jason L

“…The piRNA pathway is a specialized small RNA interference that in mosquitoes is mechanistically distant from analogous biology in the model. Current genetic…”
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The Development and Expansion of in vivo Germline Editing Technologies in Arthropods: Receptor-Mediated Ovary Transduction of Cargo (ReMOT Control) and Beyond by Terradas, Gerard, Macias, Vanessa M, Peterson, Hillary, McKeand, Sage, Krawczyk, Grzegorz, Rasgon, Jason L

“…Synopsis In the past 20 years, sequencing technologies have led to easy access to genomic data from nonmodel organisms in all biological realms. Insect genetic…”
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Gene Drive for Mosquito Control: Where Did It Come from and Where Are We Headed? by Macias, Vanessa M, Ohm, Johanna R, Rasgon, Jason L

“…Mosquito-borne pathogens place an enormous burden on human health. The existing toolkit is insufficient to support ongoing vector-control efforts towards…”
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Alpha‐mannosidase‐2 modulates arbovirus infection in a pathogen‐ and Wolbachia‐specific manner in Aedes aegypti mosquitoes by Urakova, Nadya, Joseph, Renuka E., Huntsinger, Allyn, Macias, Vanessa M., Jones, Matthew J., Sigle, Leah T., Li, Ming, Akbari, Omar S., Xi, Zhiyong, Lymperopoulos, Konstantinos, Sayre, Richard T., McGraw, Elizabeth A., Rasgon, Jason L.

“…Multiple Wolbachia strains can block pathogen infection, replication and/or transmission in Aedes aegypti mosquitoes under both laboratory and field…”
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nanos-Driven expression of piggyBac transposase induces mobilization of a synthetic autonomous transposon in the malaria vector mosquito, Anopheles stephensi by Macias, Vanessa M., Jimenez, Alyssa J., Burini-Kojin, Bianca, Pledger, David, Jasinskiene, Nijole, Phong, Celine Hien, Chu, Karen, Fazekas, Aniko, Martin, Kelcie, Marinotti, Osvaldo, James, Anthony A.

“…Transposons are a class of selfish DNA elements that can mobilize within a genome. If mobilization is accompanied by an increase in copy number (replicative…”
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Maternal germline-specific genes in the Asian malaria mosquito Anopheles stephensi: characterization and application for disease control by Biedler, James K, Qi, Yumin, Pledger, David, Macias, Vanessa M, James, Anthony A, Tu, Zhijian

“…Anopheles stephensi is a principal vector of urban malaria on the Indian subcontinent and an emerging model for molecular and genetic studies of mosquito…”
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Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi by Gantz, Valentino M, Jasinskiene, Nijole, Tatarenkova, Olga, Fazekas, Aniko, Macias, Vanessa M, Bier, Ethan, James, Anthony A

“…Genetic engineering technologies can be used both to create transgenic mosquitoes carrying antipathogen effector genes targeting human malaria parasites and to…”
Get full text

Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquitoAnopheles stephensi by Gantz, Valentino M., Jasinskiene, Nijole, Tatarenkova, Olga, Fazekas, Aniko, Macias, Vanessa M., Bier, Ethan, James, Anthony A.

“…Genetic engineering technologies can be used both to create transgenic mosquitoes carrying antipathogen effector genes targeting human malaria parasites and to…”
Get full text