Search Results - "Macias, B R"

Lower body negative pressure reduces jugular and portal vein volumes and counteracts the elevation of middle cerebral vein velocity during long-duration spaceflight by Arbeille, P., Zuj, K. A., Macias, B. R., Ebert, D. J., Laurie, S. S., Sargsyan, A. E., Martin, D. S., Lee, S. M. C., Dulchavsky, S. A., Stenger, M. B., Hargens, A. R.

“…Microgravity-induced fluid shifts markedly enlarge jugular and portal veins and increase cerebral vein velocity. These findings demonstrate a marked flow…”
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Heterogeneity of responses to orthostatic stress in homozygous twins by O'Leary, D. D, Hughson, R. L, Shoemaker, J. K, Greaves, D. K, Watenpaugh, D. E, Macias, B. R, Hargens, A. R

“…1 Department of Community Health Sciences, Brock University, St. Catharines; 2 Department of Kinesiology, University of Waterloo, Waterloo; 3 School of…”
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Cardiopulmonary deconditioning and plasma volume loss are not sufficient to provoke orthostatic hypertension by Hoenemann, J-N, Moestl, S, de Boni, L, Hoffmann, F, Arz, M, Berger, L, Pesta, D, Heusser, K, Mulder, E, Lee, S M C, Macias, B R, Tank, J, Jordan, J

“…Orthostatic hypertension, defined by an increase of systolic blood pressure (SBP) of ≥20 mmHg upon standing, harbors an increased cardiovascular risk. We…”
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Simulating the Lunar Environment: Partial Weightbearing and High-LET Radiation-Induce Bone Loss and Increase Sclerostin-Positive Osteocytes by Macias, B. R., Lima, F., Swift, J. M., Shirazi-Fard, Y., Greene, E. S., Allen, M. R., Fluckey, J., Hogan, H. A., Braby, L., Wang, Suojin, Bloomfield, S. A.

“…Exploration missions to the Moon or Mars will expose astronauts to galactic cosmic radiation and low gravitational fields. Exposure to reduced weightbearing…”
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Simulated resistance training, but not alendronate, increases cortical bone formation and suppresses sclerostin during disuse by Macias, B R, Swift, J M, Nilsson, M I, Hogan, H A, Bouse, S D, Bloomfield, S A

“…Mechanical loading modulates the osteocyte-derived protein sclerostin, a potent inhibitor of bone formation. We hypothesized that simulated resistance training…”
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Lower body negative pressure treadmill exercise is more comfortable and produces similar physiological responses as weighted vest exercise by Macias, B R, Groppo, E R, Bawa, M, Tran Cao, H S, Lee, B, Pedowitz, R A, Hargens, A R

“…Lower body negative pressure (LBNP) treadmill exercise can generate a hypergravity load on the lower body that may improve athlete performance by mechanical…”
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Evaluation of Treadmill Exercise in a Lower Body Negative Pressure Chamber as a Countermeasure for Weightlessness-Induced Bone Loss: a Bed Rest Study with Identical Twins by Smith, Scott M., Davis-Street, Janis E., Fesperman, J. Vernell, Calkins, D. S., Bawa, Maneesh, Macias, Brandon R., Meyer, R. Scott, Hargens, Alan R.

“…Counteracting bone loss is required for future space exploration. We evaluated the ability of treadmill exercise in a LBNP chamber to counteract bone loss in a…”
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Cardiac atrophy in women following bed rest by Dorfman, T. A., Levine, B. D., Tillery, T., Peshock, R. M., Hastings, J. L., Schneider, S. M., Macias, B. R., Biolo, G., Hargens, A. R.

“…Both chronic microgravity exposure and long‐duration bed rest induce cardiac atrophy, which leads to reduced standing stroke volume and orthostatic…”
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Space exercise and Earth benefits by Macias, Brandon R, Groppo, Eli R, Eastlack, Robert K, Watenpaugh, Donald E, Lee, Stuart M C, Schneider, Suzanne M, Boda, Wanda L, Smith, Scott M, Cutuk, Adnan, Pedowitz, Robert A, Meyer, R Scott, Hargens, Alan R

“…The detrimental impact of long duration space flight on physiological systems necessitates the development of exercise countermeasures to protect work…”
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WISE-2005: Supine treadmill exercise within lower body negative pressure and flywheel resistive exercise as a countermeasure to bed rest-induced bone loss in women during 60-day simulated microgravity by Smith, Scott M, Zwart, Sara R, Heer, Martina, Lee, Stuart M.C, Baecker, Natalie, Meuche, Sabine, Macias, Brandon R, Shackelford, Linda C, Schneider, Suzanne, Hargens, Alan R

“…Abstract Bone loss associated with disuse during bed rest (BR), an analog of space flight, can be attenuated by exercise. In previous studies, the efficacy of…”
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Simulated resistance training, but not alendronate, increases cortical bone formation and suppresses sclerostin during disuse by MACIAS, B. R, SWIFT, J. M, NILSSON, M. I, HOGAN, H. A, BOUSE, S. D, BLOOMFIELD, S. A

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Lumbar Spine Paraspinal Muscle and Intervertebral Disc Height Changes in Astronauts After Long-Duration Spaceflight on the International Space Station by Chang, Douglas G., Healey, Robert M., Snyder, Alexander J., Sayson, Jojo V., Macias, Brandon R., Coughlin, Dezba G., Bailey, Jeannie F., Parazynski, Scott E., Lotz, Jeffrey C., Hargens, Alan R.

“…STUDY DESIGN.Prospective case series. OBJECTIVE.Evaluate lumbar paraspinal muscle (PSM) cross-sectional area and intervertebral disc (IVD) height changes…”
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Lower body negative pressure treadmill exercise as a countermeasure for bed rest-induced bone loss in female identical twins by Zwart, Sara R, Hargens, Alan R, Lee, Stuart M.C, Macias, Brandon R, Watenpaugh, Donald E, Tse, Kevin, Smith, Scott M

“…Abstract Supine weight-bearing exercise within lower body negative pressure (LBNP) alleviates some of the skeletal deconditioning induced by simulated…”
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Bone loss during partial weight bearing (1/6th gravity) is mitigated by resistance and aerobic exercise in mice by Boudreaux, R.D., Metzger, C.E., Macias, B.R., Shirazi-Fard, Y., Hogan, H.A., Bloomfield, S.A.

“…Astronauts on long duration missions continue to experience bone loss, as much as 1–2% each month, for up to 4.5 years after a mission. Mechanical loading of…”
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Supine LBNP exercise maintains exercise capacity in male twins during 30-d bed rest by LEE, Stuart M. C, SCHNEIDER, Suzanne M, BODA, Wanda L, WATENPAUGH, Donald E, MACIAS, Brandon R, MEYER, R. Scott, HARGENS, Alan R

“…Exercise capacity is reduced after both short- and long-duration exposures to microgravity. Previously, we have documented that supine treadmill exercise…”
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Abstracts: Cardiac atrophy in women following bed rest by Dorfman, T A, Levine, B D, Tillery, T, Peshock, R M, Hastings, J L, Schneider, S M, Macias, B R, Biolo, G, Hargens, A R

“…Both chronic microgravity exposure and long-duration bed rest induce cardiac atrophy, which leads to reduced standing stroke volume and orthostatic…”
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Exercise within lower body negative pressure partially counteracts lumbar spine deconditioning associated with 28-day bed rest by Cao, Peihong, Kimura, Shinji, Macias, Brandon R, Ueno, Toshiaki, Watenpaugh, Donald E, Hargens, Alan R

“…1 Department of Orthopaedic Surgery, University of California-San Diego, San Diego, California; 2 Division of Orthopedic Surgery, Department of Regenerative…”
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Cranial diameter pulsations measured by non-invasive ultrasound decrease with tilt by Ueno, Toshiaki, Ballard, Richard E, Macias, Brandon R, Yost, William T, Hargens, Alan R

“…Intracranial pressure (ICP) may play a significant role in physiological responses to microgravity by contributing to the nausea associated with microgravity…”
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Effect of pH and gaseous ammonia flow rate on the composition and structure of ammonium uranate by RODRIGUEZ, A, MACIAS B, L. R

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EUK‐134, a synthetic superoxide dismutase/catalase mimetic, protects against loss of muscle mass/body mass in diaphragm and gastrocnemius in mdx mice by Kim, Jong‐Hee, Macias, BR, Canon, C, Courtney, S, Lawler, John M

“…Abstract only Duchenne muscular dystrophy (DMD) is characterized by devastating muscle degeneration associated with oxidative stress, loss of contractile…”
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