Search Results - "Maciag, Anna"

Global Analysis of the Mycobacterium tuberculosis Zur (FurB) Regulon by MACIAG, Anna, DAINESE, Elisa, RODRIGUEZ, G. Marcela, MILANO, Anna, PROVVEDI, Roberta, PASCA, Maria R, SMITH, Issar, PALU, Giorgio, RICCARDI, Giovanna, MANGANELLI, Riccardo

“…AUTHOR'S CORRECTION ( vol. 189 , p. 4974 ) Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
Get full text

Antioxidant effects of resveratrol in cardiovascular, cerebral and metabolic diseases by Carrizzo, Albino, Forte, Maurizio, Damato, Antonio, Trimarco, Valentina, Salzano, Francesco, Bartolo, Michelangelo, Maciag, Anna, Puca, Annibale A., Vecchione, Carmine

“…•Increasing information about resveratrol metabolism.•We focused on antioxidant effects of resveratrol.•We highlight the molecular mechanisms involved in…”
Get full text

Longevity-Associated Variant of BPIFB4 Confers Neuroprotection in the STHdh Cell Model of Huntington Disease by Cattaneo, Monica, Maciag, Anna, Milella, Maria Serena, Ciaglia, Elena, Bruno, Antonino, Puca, Annibale Alessandro

“…Huntington's disease (HD) is caused by the production of mutant Huntingtin (mHTT), characterized by long polyglutamine repeats with toxic effects. There are…”
Get full text

Activation of different split functionalities on re-association of RNA–DNA hybrids by Afonin, Kirill A., Viard, Mathias, Martins, Angelica N., Lockett, Stephen J., Maciag, Anna E., Freed, Eric O., Heldman, Eliahu, Jaeger, Luc, Blumenthal, Robert, Shapiro, Bruce A.

“…Split-protein systems, an approach that relies on fragmentation of proteins with their further conditional re-association to form functional complexes, are…”
Get full text

Revealing the mechanism of action of a first-in-class covalent inhibitor of KRASG12C (ON) and other functional properties of oncogenic KRAS by 31P NMR by Sharma, Alok K., Pei, Jun, Yang, Yue, Dyba, Marcin, Smith, Brian, Rabara, Dana, Larsen, Erik K., Lightstone, Felice C., Esposito, Dominic, Stephen, Andrew G., Wang, Bin, Beltran, Pedro J., Wallace, Eli, Nissley, Dwight V., McCormick, Frank, Maciag, Anna E.

“…Individual oncogenic KRAS mutants confer distinct differences in biochemical properties and signaling for reasons that are not well understood. KRAS activity…”
Get full text

Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis by Villa, Francesco, Carrizzo, Albino, Spinelli, Chiara C, Ferrario, Anna, Malovini, Alberto, Maciąg, Anna, Damato, Antonio, Auricchio, Alberto, Spinetti, Gaia, Sangalli, Elena, Dang, Zexu, Madonna, Michele, Ambrosio, Mariateresa, Sitia, Leopoldo, Bigini, Paolo, Calì, Gaetano, Schreiber, Stefan, Perls, Thomas, Fucile, Sergio, Mulas, Francesca, Nebel, Almut, Bellazzi, Riccardo, Madeddu, Paolo, Vecchione, Carmine, Puca, Annibale A

“…RATIONALE:Long living individuals show delay of aging, which is characterized by the progressive loss of cardiovascular homeostasis, along with reduced…”
Get full text

A Top-Down Proteomic Assay to Evaluate KRAS4B-Compound Engagement by D’Ippolito, Robert A., Rabara, Dana, Blanco, Maria Abreu, Alberico, Emily, Drew, Matthew R., Ramakrishnan, Nitya, Sontan, Dara, Widmeyer, Stephanie R. T., Scheidemantle, Grace M., Messing, Simon, Turner, David, Arkin, Michelle, Maciag, Anna E., Stephen, Andrew G., Esposito, Dominic, McCormick, Frank, Nissley, Dwight V., DeHart, Caroline J.

“…Development of new targeted inhibitors for oncogenic KRAS mutants may benefit from insight into how a given mutation influences the accessibility of protein…”
Get full text

Co-transcriptional production of RNA-DNA hybrids for simultaneous release of multiple split functionalities by Afonin, Kirill A, Desai, Ravi, Viard, Mathias, Kireeva, Maria L, Bindewald, Eckart, Case, Christopher L, Maciag, Anna E, Kasprzak, Wojciech K, Kim, Taejin, Sappe, Alison, Stepler, Marissa, Kewalramani, Vineet N, Kashlev, Mikhail, Blumenthal, Robert, Shapiro, Bruce A

“…Control over the simultaneous delivery of different functionalities and their synchronized intracellular activation can greatly benefit the fields of RNA and…”
Get full text

Macrophage-dependent nitric oxide expression regulates tumor cell detachment and metastasis after IL-2/anti-CD40 immunotherapy by Weiss, Jonathan M, Ridnour, Lisa A, Back, Tim, Hussain, S Perwez, He, Peijun, Maciag, Anna E, Keefer, Larry K, Murphy, William J, Harris, Curtis C, Wink, David A, Wiltrout, Robert H

“…Using an orthotopic model of renal cell carcinoma, we showed previously that IL-2/anti-CD40 immunotherapy resulted in synergistic anti-tumor responses, whereas…”
Get full text

BPIFB4 and its longevity-associated haplotype protect from cardiac ischemia in humans and mice by Cattaneo, Monica, Aleksova, Aneta, Malovini, Alberto, Avolio, Elisa, Thomas, Anita, Alvino, Valeria Vincenza, Kilcooley, Michael, Pieronne-Deperrois, Marie, Ouvrard-Pascaud, Antoine, Maciag, Anna, Spinetti, Gaia, Kussauer, Sophie, Lemcke, Heiko, Skorska, Anna, Vasudevan, Praveen, Castiglione, Stefania, Raucci, Angela, David, Robert, Richard, Vincent, Beltrami, Antonio Paolo, Madeddu, Paolo, Puca, Annibale Alessandro

“…Long-living individuals (LLIs) escape age-related cardiovascular complications until the very last stage of life. Previous studies have shown that a…”
Get full text

Klebsiella pneumoniae-OMVs activate death-signaling pathways in Human Bronchial Epithelial Host Cells (BEAS-2B) by Dell'Annunziata, Federica, Ciaglia, Elena, Folliero, Veronica, Lopardo, Valentina, Maciag, Anna, Galdiero, Massimiliano, Puca, Annibale Alessandro, Franci, Gianluigi

“…The programmed cell death pathways of apoptosis are important in mammalian cellular protection from infections. The activation of these pathways depends on the…”
Get full text

A Model of Evolutionary Selection: The Cardiovascular Protective Function of the Longevity Associated Variant of BPIFB4 by Villa, Francesco, Carrizzo, Albino, Ferrario, Anna, Maciag, Anna, Cattaneo, Monica, Spinelli, Chiara Carmela, Montella, Francesco, Damato, Antonio, Ciaglia, Elena, Puca, Annibale Alessandro

“…Evolutionary forces select genetic variants that allow adaptation to environmental stresses. The genomes of centenarian populations could recapitulate the…”
Get full text

Efficient Catalytic Phosphate Ester Cleavage by Binuclear Zinc(II) Pyrazolate Complexes as Functional Models of Metallophosphatases by Penkova, Larysa V, Macia̧g, Anna, Rybak-Akimova, Elena V, Haukka, Matti, Pavlenko, Vadim A, Iskenderov, Turganbay S, Kozłowski, Henryk, Meyer, Franc, Fritsky, Igor O

“…A series of dizinc(II) complexes based on the pyrazolate ligands 3-[(1E)-N-hydroxyethanimidoyl]-4-methyl-1H-pyrazole-5-carboxylic acid (H 3 L 1 ),…”
Get full text

The nitric oxide prodrug JS-K and its structural analogues as cancer therapeutic agents by Maciag, Anna E, Saavedra, Joseph E, Chakrapani, Harinath

“…Nitric oxide (NO) prodrugs of the diazeniumdiolate class are routinely used as reliable sources of nitric oxide in chemical and biological laboratory settings…”
Get more information

Nitric Oxide (NO) Releasing Poly ADP-ribose Polymerase 1 (PARP-1) Inhibitors Targeted to Glutathione S‑Transferase P1-Overexpressing Cancer Cells by Maciag, Anna E, Holland, Ryan J, Kim, Youseung, Kumari, Vandana, Luthers, Christina E, Sehareen, Waheed S, Biswas, Debanjan, Morris, Nicole L, Ji, Xinhua, Anderson, Lucy M, Saavedra, Joseph E, Keefer, Larry K

“…We report the antitumor effects of nitric oxide (NO) releasing derivatives of the PARP-1 inhibitor olaparib (1). Compound 5b was prepared by coupling the…”
Get full text

The nitric oxide prodrug JS-K is effective against non-small-cell lung cancer cells in vitro and in vivo: involvement of reactive oxygen species by Maciag, Anna E, Chakrapani, Harinath, Saavedra, Joseph E, Morris, Nicole L, Holland, Ryan J, Kosak, Ken M, Shami, Paul J, Anderson, Lucy M, Keefer, Larry K

“…Non-small-cell lung cancer is among the most common and deadly forms of human malignancies. Early detection is unusual, and there are no curative therapies in…”
Get more information

Diazeniumdiolated carbamates: A novel class of nitric oxide donors by Nandurdikar, Rahul S., Maciag, Anna E., Cao, Zhao, Keefer, Larry K., Saavedra, Joseph E.

“…We report an indirect method for synthesis of previously inaccessible diazeniumdiolated carbamates. Synthesis involves use of previously reported…”
Get full text

Denture-Related Stomatitis Is Associated with Endothelial Dysfunction by Osmenda, Grzegorz, Maciąg, Joanna, Nowakowski, Daniel, Wilk, Grzegorz, Maciąg, Anna, Mikołajczyk, Tomasz, Nosalski, Ryszard, Sagan, Agnieszka, Filip, Magdalena, Dróżdż, Mirosław, Loster, Jolanta, Guzik, Tomasz J., Cześnikiewicz-Guzik, Marta

“…Oral inflammation, such as periodontitis, can lead to endothelial dysfunction, accelerated atherosclerosis, and vascular dysfunction. The relationship between…”
Get full text

NMR 1H, 13C, 15N backbone resonance assignments of the T35S and oncogenic T35S/Q61L mutants of human KRAS4b in the active, GppNHp-bound conformation by Sharma, Alok K., Dyba, Marcin, Tonelli, Marco, Smith, Brian, Gillette, William K., Esposito, Dominic, Nissley, Dwight V., McCormick, Frank, Maciag, Anna E.

“…RAS proteins cycling between the active-form (GTP-bound) and inactive-form (GDP-bound) play a key role in cell signaling pathways that control cell survival,…”
Get full text

Determining KRAS4B-Targeting Compound Specificity by Top-Down Mass Spectrometry by D'Ippolito, Robert A, Scheidemantle, Grace M, Rabara, Dana, Abreu Blanco, Maria, Ramakrishnan, Nitya, Widmeyer, Stephanie R T, Messing, Simon, Turner, David, Maciag, Anna E, Stephen, Andrew G, Esposito, Dominic, McCormick, Frank, Nissley, Dwight V, DeHart, Caroline J

“…We present a novel method to determine engagement and specificity of KRAS4B-targeting compounds in vitro. By employing top-down mass spectrometry (MS), which…”
Get more information