Search Results - "Machumi, Francis"
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Chemical composition of essential oils from Eucalyptus globulus and Eucalyptus maculata grown in Tanzania
Published in Scientific African (01-07-2021)“…This study examined the chemical composition of essential oil from the leaves of Eucalyptus maculata and Eucalyptus globulus found in Tanzania. The chemical…”
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The effect of an anti-malarial herbal remedy, Maytenus senegalensis, on electrocardiograms of healthy Tanzanian volunteers
Published in Malaria journal (12-04-2024)“…The emergence of resistance to artemisinin-based combination therapy necessitates the search for new, more potent antiplasmodial compounds, including herbal…”
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Antimycobacterial activity of scopoletin from ethanolic extract of Hymenodictyon floribundum (Hochst. & Steud.) B.L.Rob. Stem bark
Published in Scientific African (01-09-2023)“…The available tuberculosis (TB) therapies are taken for long time with complex regimens associated with adverse effects and drug-drug interactions. The…”
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Bioassay-guided isolation of antimycobacterial compounds from Aphloia theiformis (Vahl) Benn root ethanolic extract
Published in Phytomedicine Plus : International journal of phytotherapy and phytopharmacology (01-02-2023)“…•Ethanolic root extract active against different mycobacteria species.•Bioassay guided isolation led in tormentic acid and proanthocyanidin…”
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Safety and tolerability of an antimalarial herbal remedy in healthy volunteers: An open-label, single-arm, dose-escalation study on 'Maytenus senegalensis' in Tanzania
Published in Tropical medicine and infectious disease (25-11-2022)“…Background: Though 'Maytenus senegalensis' is one of the medicinal plants widely used in traditional medicine to treat infectious and inflammatory diseases in…”
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Antiparasitic Activity of Some Xanthones and Biflavonoids from the Root Bark of Garcinia livingstonei
Published in Journal of natural products (Washington, D.C.) (01-03-2006)“…A new biflavanoid, ent-naringeninyl-(I-3α,II-8)-4‘-O-methylnaringenin (6), along with five known xanthones and two known biflavonoids, was isolated from the…”
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Safety evaluation and bioassay-guided isolation of antimycobacterial compounds from Morella salicifolia root ethanolic extract
Published in Journal of ethnopharmacology (05-10-2022)“…ETHNOPHARMACOLOGICAL RELEVANCEAlthough the available medicines can cure almost all tuberculosis drug-susceptible patients some problems including the emergence…”
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Two mosquito larvicidal arabinofuranosidetridecanol from Commiphora merkeri exudate
Published in Natural product research (01-06-2022)“…Two new arabinofuranosidetridecanol, namely 1,2-tridecanediol-1-O-α-L-5'-acetylarabinofuranoside (1) and 1,2-tridecanediol-1-O-α-L-arabinofuranoside (2)…”
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Structural Elucidation and Toxicity Evaluation of Bioactive Compounds from the Leaves and Stem woods of Synadenium glaucescens Pax
Published in Pharmaceutical sciences and research (01-08-2022)“…The leaves and stem woods of Synadenium glaucescens Pax. are traditionally used for treatment of various human diseases in Tanzania. However, there is limited…”
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Screening of Plants Used as Traditional Anticancer Remedies in Mkuranga and Same Districts, Tanzania, Using Brine Shrimp Toxicity Bioassay
Published in Evidence-based complementary and alternative medicine (01-01-2018)“…Background. Inadequate specialized cancer hospitals and high costs are contributing factors that delay cancer patients from accessing health care services in…”
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Therapeutic potential of Zanha africana (Radlk.) Exell: antimycobacterial activity and safety evaluation
Published in Scientific African (01-12-2024)“…Zanha africana (Radlk.) Exell extracts are commonly utilized in Tanzania and other countries for treating conditions associated with HIV and AIDS, including…”
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Isolation of a new cytotoxic compound, 3-((Z)-heptadec-14-enyl) benzene - 1-ol from Rhus natalensis root extract
Published in Phytochemistry letters (01-04-2020)“…•The new compound, 3-((Z)-heptadec-14-enyl) benzene -1-ol was isolated from root extract of R. natalensis.•The ethyl acetate extract of R. natalensis revealed…”
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Antimicrobial and antiparasitic abietane diterpenoids from the roots of Clerodendrum eriophyllum
Published in Natural product communications (01-06-2010)“…Chromatographic separation of the roots of a Kenyan medicinal plant, Clerodendrum eriophyllum, led to the isolation of ten abietane diterpenoids (1-10), one of…”
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Preparation and application of reversed phase Chromatorotor for the isolation of natural products by centrifugal preparative chromatography
Published in Natural product communications (01-03-2013)“…A method of preparation of rotors with a reversed phase (RP) solid silica gel sorbent layer has been developed for centrifugal preparative chromatography…”
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Antiparasitic and anticancer carvotacetone derivatives of Sphaeranthus bullatus
Published in Natural product communications (01-09-2012)“…The CH2Cl2-MeOH (1:1) extract of the aerial parts of Sphaeranthus bullatus, an annual herb native to tropical East Africa, showed activity against chloroquine…”
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Anti-plasmodial activity of Norcaesalpin D and extracts of four medicinal plants used traditionally for treatment of malaria
Published in BMC complementary and alternative medicine (24-03-2017)“…Malaria is an old life-threatening parasitic disease that is still affecting many people, mainly children living in sub-Saharan Africa. Availability of…”
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