Search Results - "Machalinski, Adeline H"

Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer's disease by Ocañas, Sarah R, Pham, Kevin D, Cox, Jillian E J, Keck, Alex W, Ko, Sunghwan, Ampadu, Felix A, Porter, Hunter L, Ansere, Victor A, Kulpa, Adam, Kellogg, Collyn M, Machalinski, Adeline H, Thomas, Manu A, Wright, Zsabre, Chucair-Elliott, Ana J, Freeman, Willard M

“…Microglia, the brain's principal immune cells, have been implicated in the pathogenesis of Alzheimer's disease (AD), a condition shown to affect more females…”
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Differential usage of DNA modifications in neurons, astrocytes, and microglia by Tooley, Kyla B, Chucair-Elliott, Ana J, Ocañas, Sarah R, Machalinski, Adeline H, Pham, Kevin D, Hoolehan, Walker, Kulpa, Adam M, Stanford, David R, Freeman, Willard M

“…Cellular identity is determined partly by cell type-specific epigenomic profiles that regulate gene expression. In neuroscience, there is a pressing need to…”
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Specificity and efficiency of tamoxifen-mediated Cre induction is equivalent regardless of age by Kellogg, Collyn M., Pham, Kevin, Ko, Sunghwan, Cox, Jillian E.J., Machalinski, Adeline H., Stout, Michael B., Sharpe, Amanda L., Beckstead, Michael J., Chucair-Elliott, Ana J., Ocañas, Sarah R., Freeman, Willard M.

“…Temporally controlling Cre recombination through tamoxifen (Tam) induction has many advantages for biomedical research. Most studies report early…”
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Minimizing the Ex Vivo Confounds of Cell-Isolation Techniques on Transcriptomic and Translatomic Profiles of Purified Microglia by Ocañas, Sarah R, Pham, Kevin D, Blankenship, Harris E, Machalinski, Adeline H, Chucair-Elliott, Ana J, Freeman, Willard M

“…Modern molecular and biochemical neuroscience studies require analysis of specific cellular populations derived from brain tissue samples to disambiguate cell…”
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Microglial MHC-I induction with aging and Alzheimer’s is conserved in mouse models and humans by Kellogg, Collyn M., Pham, Kevin, Machalinski, Adeline H., Porter, Hunter L., Blankenship, Harris E., Tooley, Kyla B., Stout, Michael B., Rice, Heather C., Sharpe, Amanda L., Beckstead, Michael J., Chucair-Elliott, Ana J., Ocañas, Sarah R., Freeman, Willard M.

“…Major histocompatibility complex I (MHC-I) CNS cellular localization and function is still being determined after previously being thought to be absent from…”
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Correction to: Microglial MHC‑I induction with aging and Alzheimer’s is conserved in mouse models and humans by Kellogg, Collyn M., Pham, Kevin, Machalinski, Adeline H., Porter, Hunter L., Blankenship, Harris E., Tooley, Kyla B., Stout, Michael B., Rice, Heather C., Sharpe, Amanda L., Beckstead, Michael J., Chucair‑Elliott, Ana J., Ocañas, Sarah R., Freeman, Willard M.

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