Search Results - "Machaliński, Bogusław"
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1
Genetic factors associated with age‐related macular degeneration: identification of a novel PRPH2 single nucleotide polymorphism associated with increased risk of the disease
Published in Acta ophthalmologica (Oxford, England) (01-11-2021)“…Purpose Age‐related macular degeneration (AMD) is associated with multiple environmental and genetic risk factors. Two main risk factors for AMD are variants…”
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2
Increased proinflammatory cytokines in tears correspond with conjunctival SARS-CoV-2 positivity in symptomatic COVID-19 patients
Published in Scientific reports (04-05-2022)“…Tear fluid cytokine levels may serve as biomarkers of innate immune system response against SARS-CoV-2 infection. Therefore, our aim was to analyze panel of…”
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3
Influence of TGFB1 and CTLA4 polymorphisms on calcineurin inhibitors dose and risk of acute rejection in renal transplantation
Published in Scientific reports (02-09-2021)“…Organ transplant is often the treatment of choice as it extends and improves patient life. Immunosuppressive treatment, which prevents acute rejection of the…”
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4
Bortezomib induces methylation changes in neuroblastoma cells that appear to play a significant role in resistance development to this compound
Published in Scientific reports (10-05-2021)“…The anticancer activity of bortezomib (BTZ) has been increasingly studied in a number of indications and promising results for the use of this treatment have…”
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5
VEGFR and DPP-IV as Markers of Severe COVID-19 and Predictors of ICU Admission
Published in International journal of molecular sciences (01-12-2023)“…The pathophysiology of the severe course of COVID-19 is multifactorial and not entirely elucidated. However, it is well known that the hyperinflammatory…”
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6
CXCL8, CCL2, and CMV Seropositivity as New Prognostic Factors for a Severe COVID-19 Course
Published in International journal of molecular sciences (01-10-2022)“…The exact pathophysiology of severe COVID-19 is not entirely elucidated, but it has been established that hyperinflammatory responses and cytokine storms play…”
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7
Apoptosis Evaluation in Circulating CD34+-Enriched Hematopoietic Stem and Progenitor Cells in Patients with Abnormally Increased Production of Endogenous Glucocorticoids in Course of Cushing's Syndrome
Published in International journal of molecular sciences (13-12-2022)“…Abnormalities in hematological parameters of peripheral blood have been noted in patients with endogenous Cushing's Syndrome (CS) in the corticotropin…”
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Epigenetic activation of antiviral sensors and effectors of interferon response pathways during SARS-CoV-2 infection
Published in Biomedicine & pharmacotherapy (01-09-2022)“…Recent studies have shown that methylation changes identified in blood cells of COVID-19 patients have a potential to be used as biomarkers of SARS-CoV-2…”
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Differential Secretion of Angiopoietic Factors and Expression of MicroRNA in Umbilical Cord Blood from Healthy Appropriate-For-Gestational-Age Preterm and Term Newborns- in Search of Biomarkers of Angiogenesis-Related Processes in Preterm Birth
Published in International journal of molecular sciences (14-02-2020)“…Premature birth, defined as less than 37 weeks gestation, affects approximately 12% of all live births around the world. Advances in neonatal care have…”
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10
Associations of microRNAs, Angiogenesis-Regulating Factors and CFH Y402H Polymorphism-An Attempt to Search for Systemic Biomarkers in Age-Related Macular Degeneration
Published in International journal of molecular sciences (15-11-2019)“…Age-related macular degeneration (AMD) remains the leading cause of blindness in elderly people, but the pathophysiology of this disease is still largely…”
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11
Mobilization of Bone Marrow-Derived Oct-4+ SSEA-4+ Very Small Embryonic-Like Stem Cells in Patients With Acute Myocardial Infarction
Published in Journal of the American College of Cardiology (06-01-2009)“…Objectives This study sought to assess of the mobilization of nonhematopoietic very small embryonic-like stem cells (VSELs) in acute myocardial infarction…”
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12
Assessment of Extracellular Matrix Fibrous Elements in Male Dermal Aging: A Ten-Year Follow-Up Preliminary Case Study
Published in Biology (Basel, Switzerland) (01-08-2024)“…Skin aging is a complex phenomenon influenced by multiple internal and external factors that can lead to significant changes in skin structure, particularly…”
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13
Response of Skin-Derived and Metastatic Human Malignant Melanoma Cell Lines to Thymoquinone and Thymoquinone-Loaded Liposomes
Published in Pharmaceutics (27-10-2022)“…Thymoquinone has been proved to be effective against neoplasms, including skin cancer. Its high lipophilicity, however, may limit its potential use as a drug…”
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14
Local and Systemic Humoral Response to Autologous Lineage-Negative Cells Intrathecal Administration in ALS Patients
Published in International journal of molecular sciences (06-02-2020)“…Amyotrophic lateral sclerosis (ALS) remains a fatal disease with limited therapeutic options. Signaling via neurotrophins (NTs), neuroinflammation, and certain…”
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15
Novel Evidence of the Increase in Angiogenic Factor Plasma Levels after Lineage-Negative Stem/Progenitor Cell Intracoronary Infusion in Patients with Acute Myocardial Infarction
Published in International journal of molecular sciences (06-07-2019)“…Cell therapy raises hope to reduce the harmful effects of acute myocardial ischemia. Stem and progenitor cells (SPCs) may be a valuable source of trophic…”
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16
Standardized astragalus extract for attenuation of the immunosuppression induced by strenuous physical exercise: randomized controlled trial
Published in Journal of the International Society of Sports Nutrition (16-07-2021)“…Background This paper aimed to verify how a supplementation of rower's diet with Astragalus Membranaceus Root (AMR) modulated their immune system response to…”
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17
Safety and Feasibility of Lin- Cells Administration to ALS Patients: A Novel View on Humoral Factors and miRNA Profiles
Published in International journal of molecular sciences (27-04-2018)“…Therapeutic options for amyotrophic lateral sclerosis (ALS) are still limited. Great hopes, however, are placed in growth factors that show neuroprotective…”
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Secondary Hemophagocytic Syndrome in a Patient with Plasma Cell Myeloma and CNS Involvement Treated with Lenalidomide
Published in Medicina (Kaunas, Lithuania) (01-09-2022)“…We present an extremely rare case report of a 29-year-old multiple myeloma patient with central nervous system involvement and secondary hemophagocytic…”
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The Importance of Platelet‐Derived Growth Factors as Markers of Survival and Severity of COVID‐19 in Patients Undergoing Monthly Follow‐Up
Published in Mediators of inflammation (01-01-2024)“…Platelets are the first to reach the site of tissue damage and secrete substances like platelet growth factors (GFs), which perform many different functions in…”
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20
Sodium Iodate Selectively Injuries the Posterior Pole of the Retina in a Dose-Dependent Manner: Morphological and Electrophysiological Study
Published in Neurochemical research (01-11-2010)“…Sequential morphological and functional features of retinal damage in mice exposed to different doses (40 vs. 20 mg/kg) of sodium iodate (NaIO 3 ) were…”
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