Search Results - "Machado‐Souza, Cleber"
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A robust platform for integrative spatial multi‐omics analysis to map immune responses to SARS‐CoV ‐2 infection in lung tissues
Published in Immunology (01-11-2023)“…Abstract The SARS‐CoV‐2 (COVID‐19) virus has caused a devastating global pandemic of respiratory illness. To understand viral pathogenesis, methods are…”
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Whole transcriptome profiling of placental pathobiology in SARS‐CoV‐2 pregnancies identifies placental dysfunction signatures
Published in Clinical & translational immunology (2024)“…Objectives Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) virus infection in pregnancy is associated with higher incidence of placental…”
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A complete physical mapping of the vitamin D receptor gene for dental implant loss: A pilot study
Published in Clinical oral implants research (01-12-2019)“…Objectives The aim of this pilot case–control study was to investigate the association of clinical variables and genetic polymorphisms in the vitamin D…”
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Gene-environment interaction in molar-incisor hypomineralization
Published in PloS one (06-01-2021)“…Molar incisor hypomineralization (MIH) is an enamel condition characterized by lesions ranging in color from white to brown which present rapid caries…”
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The role of Phosphatidylinositol 3 kinase (PI3K) and Cycloxygenase-2 (COX2) in carcinogenesis of colorectal polyps
Published in Journal of Coloproctology (01-01-2018)“…Determine immunohistochemical expression of Phosphatase and tensin homolog (PTEN), Phosphatidylinositol 3 kinase (PI3K), Cycloxygenase-2 (COX2) and one…”
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Association Between COVID-19 Pregnant Women Symptoms Severity and Placental Morphologic Features
Published in Frontiers in immunology (26-05-2021)“…Since the beginning of the pandemic, few papers describe the placenta’s morphological and morphometrical features in SARS-CoV-2–positive pregnant women…”
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Editorial: Reducing adverse effects of cancer immunotherapy
Published in Frontiers in immunology (01-02-2024)Get full text
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COVID-19 and Lung Mast Cells: The Kallikrein-Kinin Activation Pathway
Published in International journal of molecular sciences (02-02-2022)“…Mast cells (MCs) have relevant participation in inflammatory and vascular hyperpermeability events, responsible for the action of the kallikrein-kinin system…”
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Lung Inflammasome Activation in SARS-CoV-2 Post-Mortem Biopsies
Published in International journal of molecular sciences (27-10-2022)“…The inflammasome complex is a key part of chronic diseases and acute infections, being responsible for cytokine release and cell death mechanism regulation…”
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Lung Neutrophilic Recruitment and IL-8/IL-17A Tissue Expression in COVID-19
Published in Frontiers in immunology (30-03-2021)“…The new SARS-CoV-2 virus differs from the pandemic Influenza A virus H1N1 subtype (H1N1pmd09) how it induces a pro-inflammatory response in infected patients…”
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Immune Response Gaps Linked to SARS-CoV-2 Infection: Cellular Exhaustion, Senescence, or Both?
Published in International journal of molecular sciences (08-11-2022)“…The COVID-19 pandemic, promoted by the SARS-CoV-2 respiratory virus, has resulted in widespread global morbidity and mortality. The immune response against…”
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IL17A and IL17RA gene polymorphisms in Fanconi anemia
Published in Brazilian oral research (01-01-2023)“…Fanconi anemia is a rare autosomal recessive disease. In this disease, cytokine pathways can induce the bone marrow failure that is observed in individuals…”
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Role of Genetic Polymorphism Present in Macrophage Activation Syndrome Pathway in Post Mortem Biopsies of Patients with COVID-19
Published in Viruses (31-07-2022)“…COVID-19 is a viral disease associated with an intense inflammatory response. Macrophage Activation Syndrome (MAS), the complication present in secondary…”
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Types of External Root Resorption of Replanted Teeth: Analysis of the Clinical Aspects and of Interleukin-4 Gene Polymorphisms Involvement
Published in Journal of endodontics (01-11-2017)“…The absence or presence of root resorption on the surface of a replanted tooth indicates an immune-inflammatory reaction. Recent research even suggests the…”
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The role of polymorphism of the IL6 gene in tooth replantation
Published in Australian endodontic journal (01-08-2021)“…The absence or presence of root resorption on the root surface of a replanted tooth indicates an immune‐inflammatory reaction. Since interleukin‐6 (IL‐6) is…”
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In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection
Published in EBioMedicine (01-03-2024)“…The utilization of single-cell resolved spatial transcriptomics to delineate immune responses during SARS-CoV-2 infection was able to identify M1 macrophages…”
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Association of clinical variables and polymorphisms in RANKL, RANK, and OPG genes with external apical root resorption
Published in American journal of orthodontics and dentofacial orthopedics (01-04-2019)“…The aim of this study was to investigate the association of clinical variables and polymorphisms in the RANKL, RANK, and OPG genes with external apical root…”
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The role of IL17 and IL17RA polymorphisms in lethal pandemic acute viral pneumonia (Influenza A virus H1N1 subtype)
Published in Surgical and experimental pathology (08-02-2023)“…Abstract Background The cytokines play an essential role in acute inflammatory processes, and the IL-17 may be responsible for ambiguous aspects, and the…”
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Parkin and its molecular associations in gliomas – a systematic review
Published in Surgical and experimental pathology (05-05-2021)“…Abstract Parkin, a protein encoded by PRKN, discovered in the context of Parkinson’s disease, controls proteasomal degradation by protein ubiquitination and…”
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Association between vitamin D receptor gene polymorphisms and susceptibility to chronic kidney disease and periodontitis
Published in Blood purification (01-01-2007)“…Chronic kidney disease (CKD) and periodontitis (PD) are serious public-health concerns. Vitamin D is a fat-soluble steroid hormone that interacts with its…”
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