Search Results - "Machado, U.F"
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Identification of nuclear factor-κB sites in the Slc2a4 gene promoter
Published in Molecular and cellular endocrinology (06-05-2013)“…► Two κB sites have been identified in the Slc2a4 gene. ► One of the identified κB sites has a direct repressor effect in the Slc2a4 gene expression. ► An…”
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The Na(+)/glucose cotransporters: from genes to therapy
Published in Brazilian journal of medical and biological research (01-11-2010)“…Glucose enters eukaryotic cells via two types of membrane-associated carrier proteins, the Na(+)/glucose cotransporters (SGLT) and the facilitative glucose…”
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Changes in sodium or glucose filtration rate modulate expression of glucose transporters in renal proximal tubular cells of rat
Published in The Journal of membrane biology (15-07-2001)“…Renal glucose reabsorption is mediated by luminal sodium-glucose cotransporters (SGLTs) and basolateral facilitative glucose transporters (GLUTs). The…”
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Reduced cortical renal GLUT1 expression induced by angiotensin-converting enzyme inhibition in diabetic spontaneously hypertensive rats
Published in Brazilian journal of medical and biological research (01-11-2008)“…Diabetes in spontaneously hypertensive rats is associated with cortical renal GLUT1 and GLUT2 overexpression. Our objective was to evaluate the effect of the…”
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Low ethanol consumption increases insulin sensitivity in Wistar rats
Published in Brazilian journal of medical and biological research (01-01-2003)“…Several human studies suggest that light-to-moderate alcohol consumption is associated with enhanced insulin sensitivity, but these studies are not free of…”
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Aerobic exercise training reduces insulin resistance and atherogenesis induced by low-sodium diet in LDL receptor knockout mice
Published in Atherosclerosis (01-08-2021)Get full text
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GLUT4 protein expression in obese and lean 12-month-old rats: insights from different types of data analysis
Published in Brazilian journal of medical and biological research (01-10-2001)“…GLUT4 protein expression in white adipose tissue (WAT) and skeletal muscle (SM) was investigated in 2-month-old, 12-month-old spontaneously obese or…”
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Abnormal subcellular distribution of GLUT4 protein in obese and insulin-treated diabetic female dogs
Published in Brazilian journal of medical and biological research (01-07-2004)“…The GLUT4 transporter plays a key role in insulin-induced glucose uptake, which is impaired in insulin resistance. The objective of the present study was to…”
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Low-sodium diet increases insulin resistance and favors fat accumulation in the liver of LDL receptor knockout mice
Published in Atherosclerosis (01-12-2020)Get full text
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Baroreflex and chemoreflex dysfunction in streptozotocin-diabetic rats
Published in Brazilian journal of medical and biological research (01-01-1997)“…Several investigators have demonstrated that streptozotocin (STZ) diabetes induces changes in the autonomic control of the cardiovascular system. Changes in…”
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Improvement of glycemic control restores ABCA-1 in macrophages incubated with albumin isolated from diabetic subjects
Published in Atherosclerosis (01-08-2018)Get full text
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SLC2A2 gene expression in kidney of diabetic rats is regulated by HNF-1α and HNF-3β
Published in Molecular and cellular endocrinology (16-06-2009)“…We hypothesize that, in kidney of diabetic rats, hepatocyte nuclear factors (HNF-1α and HNF-3β) play a critical role in the overexpression of solute carrier…”
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Association of single nucleotide polymorphisms in the gene encoding GLUT1 and diabetic nephropathy in Brazilian patients with type 1 diabetes mellitus
Published in Clinica chimica acta (15-04-2015)“…Mesangial cells subject to high extracellular glucose concentrations, as occur in hyperglycaemic states, are unable to down regulate glucose influx, resulting…”
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Obesity is the major cause of alterations in insulin secretion and calcium fluxes by isolated islets from aged rats
Published in Physiology & behavior (01-10-1992)“…To investigate the alterations in insulin secretion induced by aging, 2-month-old, 12-month-old, and 12-month old lean rats (submitted to a caloric restriction…”
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Glimepiride as insulin sensitizer: increased liver and muscle responses to insulin
Published in Diabetes, obesity & metabolism (01-07-2008)“…Glimepiride, a low-potency insulin secretagogue, is as efficient on glycaemic control as other sulphonylureas, suggesting an additional insulin-sensitizer…”
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Insulin secretion in the isolated islets of single-, regular-fasted and fed rats
Published in Physiology & behavior (01-05-1989)“…To investigate the alterations in insulin secretion induced by habituation to single daily meal, adult rats were trained on a regular-fasting scheme (2-hr…”
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Neuromuscular electrical stimulation improves GLUT-4 and morphological characteristics of skeletal muscle in rats with heart failure
Published in Acta Physiologica (01-02-2011)“…Aim: Changes in skeletal muscle morphology and metabolism are associated with limited functional capacity in heart failure, which can be attenuated by…”
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Proinsulin C-peptide induces c-Jun N-terminal kinase 1 expression in LEII mouse lung capillary endothelial cells
Published in The Japanese Journal of Veterinary Research (01-11-2009)“…To characterize the roles of C-peptide in vascular homeostatic processes, we examined the genes regulated by C-peptide in LEII mouse lung microvascular…”
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Glucose uptake, glucose transporter GLUT4, and glycolytic enzymes in brown adipose tissue from rats adapted to a high-protein diet
Published in Metabolism, clinical and experimental (01-11-2002)“…In vivo rates of glucose uptake, insulin-responsive glucose transporter (GLUT4) content, and activities of glycolytic enzymes were determined in brown adipose…”
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