Search Results - "Machado, Raquel C."

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis by Knobloch, Marlen, Braun, Simon M. G., Zurkirchen, Luis, von Schoultz, Carolin, Zamboni, Nicola, Araúzo-Bravo, Marcos J., Kovacs, Werner J., Karalay, Özlem, Suter, Ueli, Machado, Raquel A. C., Roccio, Marta, Lutolf, Matthias P., Semenkovich, Clay F., Jessberger, Sebastian

“…Adult neural stem and progenitor cells (NSPCs) show high levels of fatty acid synthase (Fasn)-dependent de novo lipogenesis, a process that is controlled by…”
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Architecture and regulation of filamentous human cystathionine beta-synthase by McCorvie, Thomas J., Adamoski, Douglas, Machado, Raquel A. C., Tang, Jiazhi, Bailey, Henry J., Ferreira, Douglas S. M., Strain-Damerell, Claire, Baslé, Arnaud, Ambrosio, Andre L. B., Dias, Sandra M. G., Yue, Wyatt W.

“…Cystathionine beta-synthase (CBS) is an essential metabolic enzyme across all domains of life for the production of glutathione, cysteine, and hydrogen…”
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Emerging Roles and Potential Applications of Non-Coding RNAs in Glioblastoma by DeOcesano-Pereira, Carlos, Machado, Raquel A C, Chudzinski-Tavassi, Ana Marisa, Sogayar, Mari Cleide

“…Non-coding RNAs (ncRNAs) comprise a diversity of RNA species, which do not have the potential to encode proteins. Non-coding RNAs include two classes of RNAs,…”
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A chemical probe to modulate human GID4 Pro/N-degron interactions by Owens, Dominic D. G., Maitland, Matthew E. R., Khalili Yazdi, Aliakbar, Song, Xiaosheng, Reber, Viviane, Schwalm, Martin P., Machado, Raquel A. C., Bauer, Nicolas, Wang, Xu, Szewczyk, Magdalena M., Dong, Cheng, Dong, Aiping, Loppnau, Peter, Calabrese, Matthew F., Dowling, Matthew S., Lee, Jisun, Montgomery, Justin I., O’Connell, Thomas N., Subramanyam, Chakrapani, Wang, Feng, Adamson, Ella C., Schapira, Matthieu, Gstaiger, Matthias, Knapp, Stefan, Vedadi, Masoud, Min, Jinrong, Lajoie, Gilles A., Barsyte-Lovejoy, Dalia, Owen, Dafydd R., Schild-Poulter, Caroline, Arrowsmith, Cheryl H.

“…The C-terminal to LisH (CTLH) complex is a ubiquitin ligase complex that recognizes substrates with Pro/N-degrons via its substrate receptor Glucose-Induced…”
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L-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasiveness by Machado, Raquel A C, Stojevski, Dunja, De Landtsheer, Sébastien, Lucarelli, Philippe, Baron, Alexandre, Sauter, Thomas, Schaffner-Reckinger, Elisabeth

“…Metastasis is the predominant cause for cancer morbidity and mortality accounting for approximatively 90% of cancer deaths. The actin-bundling protein…”
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Evaluation of photobiomodulation therapy (PBMT) on salivary flow and composition in head and neck cancer patients undergoing radiation therapy by Schepanski, Natalia, Costa, Floriatan Santos, Machado, Edina Fernanda Martins, Pacheco, Milena Nunes, Amaral, Clarice D.B., Machado, Raquel C., Nogueira, Ana Rita A., Brancher, João Armando, Sassi, Laurindo Moacir, de Araujo, Melissa Rodrigues

“…Assess the impact of photobiomodulation therapy (PBMT) on xerostomia, salivary flow rate (SFR) and composition in patients undergoing radiotherapy (RT) for…”
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Multielemental Determination of As, Bi, Ge, Sb, and Sn in Agricultural Samples Using Hydride Generation Coupled to Microwave-Induced Plasma Optical Emission Spectrometry by Machado, Raquel C, Amaral, Clarice D. B, Nóbrega, Joaquim A, Araujo Nogueira, Ana Rita

“…A microwave-induced plasma optical emission spectrometer with N2-based plasma was combined with a multimode sample introduction system (MSIS) for hydride…”
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Complex samples and spectral interferences in ICP-MS: Evaluation of tandem mass spectrometry for interference-free determination of cadmium, tin and platinum group elements by Machado, Raquel C., Amaral, Clarice D.B., Schiavo, Daniela, Nóbrega, Joaquim A., Nogueira, Ana Rita A.

“…An analytical method was developed for determination of Cd, Sn, Pd, Pt and Rh in sediments, fertilizer and sludge samples by inductively coupled plasma tandem…”
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Self-organizing map applied to the choice of internal standards for the determination of Cd, Pb, Sn, and platinum group elements by inductively coupled plasma mass spectrometry by Moreira, Luana S., Costa, Floriatan S., Machado, Raquel C., Nogueira, Ana Rita A., Gonzalez, Mario H., da Silva, Erik G.P., Amaral, Clarice D.B.

“…The behaviors of internal standards, according to different flow rates of the cell collision gas (He), were studied for the determination of Cd, Pb, Pd, Pt,…”
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Novel TIE‐2 inhibitor BAY‐826 displays in vivo efficacy in experimental syngeneic murine glioma models by Schneider, Hannah, Szabo, Emese, Machado, Raquel A. C., Broggini‐Tenzer, Angela, Walter, Alexander, Lobell, Mario, Heldmann, Dieter, Süssmeier, Frank, Grünewald, Sylvia, Weller, Michael

“…Targeting the vascular endothelial growth factor signaling axis in glioblastoma inevitably leads to tumor recurrence and a more aggressive phenotype…”
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Evaluation of different nebulizers performance on microwave-induced plasma optical emission spectrometry by Silva, Ana Beatriz S., Higuera, Julymar M., Braz, Carlos Eduardo M., Machado, Raquel C., Nogueira, Ana Rita A.

“…The choice of an adequate nebulizer reflects directly in the accuracy, especially when a complex matrix is analyzed in plasma techniques. To unveil the effects…”
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Coprecipitation magnesium(II) hydroxide as a strategy of pre-concentration for trace elemental determination by microwave-induced plasma optical emission spectrometry by Moreira, Luana S., Sá, Ívero P., Machado, Raquel C., Nogueira, Ana Rita A., da Silva, Erik G.P., Amaral, Clarice D.B.

“…In this work, a method employing coprecipitation procedure with magnesium hydroxide as a carrier for separation/preconcentration of arsenic(V), cadmium(II),…”
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Silicon determination by microwave-induced plasma optical emission spectrometry: Considerations and strategies for the use of tetrafluorboric acid and sodium hydroxide in sample preparation procedures by Santos, Mykaelli A., Silva, Ana Beatriz S., Machado, Raquel C., Dias, Ellen A., Barros, Juan A.V.A., Nogueira, Ana Rita A.

“…The use of tetrafluoroboric acid and sodium hydroxide were investigated for the total decomposition of plant tissues and fertilizers for Si determination by…”
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Oral health, organic and inorganic saliva composition of men with Schizophrenia: Case-control study by Rosa, Letícia Kreutz, Costa, Floriatan Santos, Hauagge, Cecília Moraes, Mobile, Rafael Zancan, de Lima, Antonio Adilson Soares, Amaral, Clarice D.B., Machado, Raquel C., Nogueira, Ana Rita A., Brancher, João Armando, de Araujo, Melissa Rodrigues

“…[Display omitted] Schizophrenia (SCZ) presents complex challenges related to diagnosis and clinical monitoring. The study of conditions associated with SCZ can…”
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Declining lamin B1 expression mediates age-dependent decreases of hippocampal stem cell activity by bin Imtiaz, Muhammad Khadeesh, Jaeger, Baptiste N., Bottes, Sara, Machado, Raquel A.C., Vidmar, Mojca, Moore, Darcie L., Jessberger, Sebastian

“…Neural stem cells (NSCs) generate neurons throughout life in the hippocampal dentate gyrus. With advancing age, levels of neurogenesis sharply drop, which has…”
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LASER INDUCED-BREAKDOWN SPECTROSCOPY (LIBS): HISTÓRICO, FUNDAMENTOS, APLICAÇÕES E POTENCIALIDADES by Costa, Vinicius, Augusto, Amanda, Castro, Jeyne, Machado, Raquel, Andrade, Daniel, Babos, Diego, Sperança, Marco, Gamela, Raimundo, Pereira-Filho, Edenir

“…This review attempts to present a broad view of the technique laser-induced breakdown spectroscopy (LIBS), since its origin, fundamentals, sample preparation…”
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Characterization of Synchronous Vertical Dual View Inductively Coupled Plasma Optical Emission Spectrometer with Application for Water Analysis by Amaral, Clarice D. B., Schiavo, Daniela, Barros, Juan A. V. A., Machado, Raquel C., Nogueira, Ana Rita A., Nóbrega, Joaquim A.

“…The performance of an inductively coupled plasma optical emission spectrometer was evaluated using Ar, Ba, Mg, and Ni as test elements. Short- and long-term…”
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The actin-bundling protein L-plastin-A double-edged sword: Beneficial for the immune response, maleficent in cancer by Schaffner-Reckinger, Elisabeth, Machado, Raquel A C

“…The dynamic organization of the actin cytoskeleton into bundles and networks is orchestrated by a large variety of actin-binding proteins. Among them, the…”
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Epigenetic vulnerabilities of leukemia harboring inactivating EZH2 mutations by Alqazzaz, Mona A., Luciani, Genna M., Vu, Victoria, Machado, Raquel A.C., Szewczyk, Magdalena M., Adamson, Ella C., Cheon, Sehyun, Li, Fengling, Arrowsmith, Cheryl H., Minden, Mark D., Barsyte-Lovejoy, Dalia

“…•In acute myeloid leukemia and myeloproliferative/myelodysplastic disorders, loss of function (LOF) mutations in EZH2 result in lower H3K27 methylation•EZH2…”
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A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins by Ackloo, Suzanne, Li, Fengling, Szewczyk, Magda, Seitova, Almagul, Loppnau, Peter, Zeng, Hong, Xu, Jin, Ahmad, Shabbir, Arnautova, Yelena A, Baghaie, A. J., Beldar, Serap, Bolotokova, Albina, Centrella, Paolo A., Chau, Irene, Clark, Matthew A., Cuozzo, John W., Dehghani-Tafti, Saba, Disch, Jeremy S., Dong, Aiping, Dumas, Antoine, Feng, Jianwen A., Ghiabi, Pegah, Gibson, Elisa, Gilmer, Justin, Goldman, Brian, Green, Stuart R, Guié, Marie-Aude, Guilinger, John P., Harms, Nathan, Herasymenko, Oleksandra, Houliston, Scott, Hutchinson, Ashley, Kearnes, Steven, Keefe, Anthony D., Kimani, Serah W., Kramer, Trevor, Kutera, Maria, Kwak, Haejin A., Lento, Cristina, Li, Yanjun, Liu, Jenny, Loup, Joachim, Machado, Raquel A. C., Mulhern, Christopher J., Perveen, Sumera, Righetto, Germanna L., Riley, Patrick, Shrestha, Suman, Sigel, Eric A., Silva, Madhushika, Sintchak, Michael D., Slakman, Belinda L., Taylor, Rhys D., Thompson, James, Torng, Wen, Underkoffler, Carl, von Rechenberg, Moritz, Walsh, Ryan T., Watson, Ian, Wilson, Derek J., Wolf, Esther, Yadav, Manisha, Yazdi, Aliakbar K., Zhang, Junyi, Zhang, Ying, Santhakumar, Vijayaratnam, Edwards, Aled M., Barsyte-Lovejoy, Dalia, Schapira, Matthieu, Brown, Peter J., Halabelian, Levon, Arrowsmith, Cheryl H.

“…Target class-focused drug discovery has a strong track record in pharmaceutical research, yet public domain data indicate that many members of protein families…”
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