Search Results - "Machado, Rafael Rahal Guaragna"

Alphacoronavirus Detection in Lungs, Liver, and Intestines of Bats from Brazil by Bittar, Cíntia, Machado, Rafael Rahal Guaragna, Comelis, Manuela Tosi, Bueno, Larissa Mayumi, Beguelini, Mateus Rodrigues, Morielle-Versute, Eliana, Nogueira, Maurício Lacerda, Rahal, Paula

“…Bats are flying mammals distributed worldwide known to host several types of Coronavirus (CoV). Since they were reported as the probable source of spillover of…”
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Surrogate test performance for SARS‐CoV‐2 neutralizing antibodies (nAbs) for convalescent plasma (CCP): How useful could they be? by Wendel, Silvano, Fachini, Roberta, Fontão‐Wendel, Rita C. L., Mello, Ralyria, Velasquez, Carlos Vinícius, Machado, Rafael Rahal Guaragna, Brito, Mayra Altobelli, Amaral, Marcelo, Soares, Camila Pereira, Achkar, Ruth, Scuracchio, Patrícia, Miyaji, Sandra Cristina, Erdens, Melina Santos, Durigon, Edison Luiz

“…Background COVID‐19 high‐titer CCP selection is a concern, because neutralizing antibody (nAb) testing requires sophisticated labs and methods. Surrogate tests…”
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Correlation between SARS‐COV‐2 antibody screening by immunoassay and neutralizing antibody testing by Mendrone‐Junior, Alfredo, Dinardo, Carla Luana, Ferreira, Suzete Cleuza, Nishya, Anna, Salles, Nanci Alves, Almeida Neto, Cesar, Hamasaki, Debora Toshei, Facincani, Tila, Oliveira Alves, Lucas Bassolli, Machado, Rafael Rahal Guaragna, Araujo, Danielle Bastos, Durigon, Edison Luiz, Rocha, Vanderson, Sabino, Ester Cerdeira

“…Background The efficacy of convalescent plasma (CP), an alternative for the treatment of COVID‐19, depends on high titers of neutralizing antibodies (nAbs),…”
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UV-C (254 nm) lethal doses for SARS-CoV-2 by Sabino, Caetano P., Sellera, Fábio P., Sales-Medina, Douglas F., Machado, Rafael Rahal Guaragna, Durigon, Edison Luiz, Freitas-Junior, Lucio H., Ribeiro, Martha S.

“…•We developed a controlled assay to investigate the UV-C inactivation kinetics for SARS-CoV-2.•We established the UV-C lethal doses for the virus in…”
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SARS-CoV-2 isolation from the first reported patients in Brazil and establishment of a coordinated task network by Araujo, Danielle Bastos, Machado, Rafael Rahal Guaragna, Amgarten, Deyvid Emanuel, Malta, Fernanda de Mello, de Araujo, Gabriel Guarany, Monteiro, Cairo Oliveira, Candido, Erika Donizetti, Soares, Camila Pereira, de Menezes, Fernando Gatti, Pires, Ana Carolina Cornachioni, Santana, Rúbia Anita Ferraz, Viana, Amanda de Oliveira, Dorlass, Erick, Thomazelli, Luciano, Ferreira, Luis Carlos de Sousa, Botosso, Viviane Fongaro, Carvalho, Cristiane Rodrigues Guzzo, Oliveira, Danielle Bruna Leal, Pinho, João Renato Rebello, Durigon, Edison Luiz

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was confirmed in Brazil in February 2020, the first cases were followed by an increase in the…”
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Beneficial effects of a mouthwash containing an antiviral phthalocyanine derivative on the length of hospital stay for COVID-19: randomised trial by da Silva Santos, Paulo Sérgio, da Fonseca Orcina, Bernardo, Machado, Rafael Rahal Guaragna, Vilhena, Fabiano Vieira, da Costa Alves, Lucas Marques, Zangrando, Mariana Schutzer Ragghianti, de Oliveira, Rodrigo Cardoso, Soares, Mariana Quirino Silveira, Simão, Andréa Name Colado, Pietro, Emilene Cristine Izu Nakamura, Kuroda, Juliana Pescinelli Garcia, de Almeida Benjamim, Ivanilda Aparecida, Araujo, Danielle Bastos, Toma, Sérgio Hiroshi, Flor, Lourival, Araki, Koiti, Durigon, Edison Luiz

“…The risk of contamination and dissemination by SARS-CoV-2 has a strong link with nasal, oral and pharyngeal cavities. Recently, our research group observed the…”
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Nebulized enriched heparin improves respiratory parameters in patients with COVID-19: a phase I/II randomized and triple-blind clinical trial by Ramos da Silva Grillo, Vinicius Tadeu, Bertanha, Matheus, da Silva Rodrigues, Lenize, de Lima, Marcelo Andrade, Mellucci Filho, Pedro Luciano, Rahal Guaragna Machado, Rafael, Durigon, Edson Luiz, Dias Sertorio, Nathália, de Assis Golim, Marjorie, Moroz, Andrei, Marques Braz, Aline Márcia, de Moraes, Leonardo Nazário, Leite, Marco Antonio, Bonciani Nader, Helena, de Campos, Gustavo Constantino, Rodrigues Guzzo Carvalho, Cristiane, Florença Cardoso, Fábio, Magro, Angelo José, Caputo Nunes, Helga, Tommasini Grotto, Rejane Maria, de Cássia Alvarado, Rita, de Moura Campos Pardini, Maria Inês, Lima Sobreira, Marcone, da Costa, Erika Alessandra Pellison Nunes, Naime Barbosa, Alexandre, Fortaleza, Carlos Magno Castelo Branco

“…To evaluate the safety and the potential antiviral treatment of inhaled enriched heparin in patients with COVID-19. The specific objectives were to investigate…”
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Neutralizing antibody response after immunization with a COVID‐19 bivalent vaccine: Insights to the future by Souza, Milena Silva, Farias, Jéssica Pires, Andreata‐Santos, Robert, Silva, Marianne Pereira, Brito, Ruth Dálety da Silva, Duarte Barbosa da Silva, Marcia, Peter, Cristina Mendes, Cirilo, Marcus Vinícius de França, Luiz, Wilson Barros, Birbrair, Alexander, Vidal, Paloma Oliveira, Castro‐Amarante, Maria Fernanda, Candido, Erika Donizetti, Munhoz, Aldilene Silva, Mello Malta, Fernanda, Dorlass, Erik Gustavo, Machado, Rafael Rahal Guaragna, Pinho, João Renato Rebello, Oliveira, Danielle Bruna Leal, Durigon, Edison Luiz, Maricato, Juliana Terzi, Braconi, Carla Torres, Ferreira, Luís Carlos de Souza, Janini, Luiz Mário Ramos, Amorim, Jaime Henrique

“…The raising of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) variants led to the use of COVID‐19 bivalent vaccines, which include antigens of…”
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Neonatal consequences of maternal exposure to the chikungunya virus: Case reports by Fajardo, Thamirys Cosmo Grillo, Gazeta, Rosa Estela, Catalan, Daniel Thome, Mello, Alexandra Siqueira, Silva, Andrea Cristina Botelho da, Bertozzi, Ana Paula Antunes Pascalicchio, Santos, Geovane Ribeiro Dos, Pinto, Clóvis Antonio Lopes, Monteiro, Cairo Oliveira, Machado, Rafael Rahal Guaragna, Oliveira, Danielle Bruna Leal, Durigon, Edison Luiz, Passos, Saulo Duarte

“…The chikungunya virus (CHIKV) was first isolated in a Tanzanian epidemic area between 1952 and 1953. The best description of the CHIKV transmission during…”
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Nano-multilamellar lipid vesicles loaded with a recombinant form of the chikungunya virus E2 protein improve the induction of virus-neutralizing antibodies by Venceslau-Carvalho, Aléxia Adrianne, Teixeira de Pinho Favaro, Marianna, Ramos Pereira, Lennon, Rodrigues-Jesus, Mônica Josiane, Santos Pereira, Samuel, Andreata-Santos, Robert, dos Santos Alves, Rúbens Prince, Castro-Amarante, Maria Fernanda, Bitencourt Rodrigues, Karine, Ramos da Silva, Jamile, Rahal Guaragna Machado, Rafael, dos Passos Cunha, Marielton, Marinho de Andrade Zanotto, Paolo, Luzetti Fotoran, Wesley, Wunderlich, Gerhard, Durigon, Edison Luiz, de Souza Ferreira, Luís Carlos

“…Chikungunya virus (CHIKV) is responsible for a self-limited illness that can evolve into long-lasting painful joint inflammation. In this study, we report a…”
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COVID‐19 convalescent plasma cohort study: Evaluation of the association between both donor and recipient neutralizing antibody titers and patient outcomes by Yokoyama, Ana Paula H., Wendel, Silvano, Bonet‐Bub, Carolina, Fachini, Roberta M., Dametto, Ana Paula F., Blumm, Fernando, Dutra, Valeria F., Candelaria, Gabriela T. P., Sakashita, Araci M., Machado, Rafael Rahal Guaragna, Fontão‐Wendel, Rita, Hamerschlak, Nelson, Achkar, Ruth, Assunção, Murillo Santucci Cesar, Scuracchio, Patrícia, Nudelman, Victor, Pastore, Laerte, Pinho, João R. R., Ben, Mirian Dal, Filho, Roberto Kalil, Marra, Alexandre R., Amano, Mariane T., Kallás, Esper G., Helito, Alfredo Salim, Carvalho, Carlos Roberto Ribeiro, Araujo, Danielle Bastos, Durigon, Edison Luiz, Camargo, Anamaria A., Rizzo, Luiz V., Reis, Luiz F. L., Kutner, Jose M.

“…Background Current evidence regarding COVID‐19 convalescent plasma (CCP) transfusion practices is limited and heterogeneous. We aimed to determine the impact…”
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Immunodominant antibody responses directed to SARS-CoV-2 hotspot mutation sites and risk of immune escape by Oliveira, Jamille Ramos, Ruiz, Cesar Manuel Remuzgo, Machado, Rafael Rahal Guaragna, Magawa, Jhosiene Yukari, Daher, Isabela Pazotti, Urbanski, Alysson Henrique, Schmitz, Gabriela Justamante Händel, Arcuri, Helen Andrade, Ferreira, Marcelo Alves, Sasahara, Greyce Luri, de Medeiros, Giuliana Xavier, Júnior, Roberto Carlos Vieira Silva, Durigon, Edison Luiz, Boscardin, Silvia Beatriz, Rosa, Daniela Santoro, Schechtman, Deborah, Nakaya, Helder I, Cunha-Neto, Edecio, Gadermaier, Gabriele, Kalil, Jorge, Coelho, Verônica, Santos, Keity Souza

“…Considering the likely need for the development of novel effective vaccines adapted to emerging relevant CoV-2 variants, the increasing knowledge of epitope…”
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Anti‐A and SARS‐CoV‐2: an intriguing association by Freitas Dutra, Valeria, Bonet‐Bub, Carolina, Yokoyama, Ana Paula H., Achkar, Ruth, Machado, Rafael Rahal Guaragna, Assunção, Murilo, Candelária, Gabriela, Soares, Camila Pereira, Fachini, Roberta Maria, Fontão‐Wendel, Rita, Hamerschlak, Nelson, Reis, Luiz Fernando Lima, Araujo, Danielle Bastos, Nudelman, Victor, Pinho, Joao R. R., Rizzo, Luiz V., Sakashita, Araci M., Scuracchio, Patrícia, Durigon, Edison Luiz, Wendel, Silvano, Kutner, Jose M.

“…Background Blood groups and anti‐A isohemagglutinin may be involved in susceptibility to SARS‐CoV‐2 infection. Materials and Methods We retrospectively studied…”
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Identification of Zika Virus NS1-Derived Peptides with Potential Applications in Serological Tests by Prudencio, Carlos Roberto, Gomes da Costa, Vivaldo, Rocha, Leticia Barboza, Costa, Hernan Hermes Monteiro, Orts, Diego José Belato, da Silva Santos, Felipe Rocha, Rahal, Paula, Lino, Nikolas Alexander Borsato, da Conceição, Pâmela Jóyce Previdelli, Bittar, Cintia, Machado, Rafael Rahal Guaragna, Durigon, Edison Luiz, Araujo, Jr, João Pessoa, Polatto, Juliana Moutinho, da Silva, Miriam Aparecida, de Oliveira, Joyce Araújo, Mitsunari, Thais, Pereira, Lennon Ramos, Andreata-Santos, Robert, de Souza Ferreira, Luís Carlos, Luz, Daniela, Piazza, Roxane Maria Fontes

“…Zika virus (ZIKV), a mosquito-borne pathogen, is an emerging arbovirus associated with sporadic symptomatic cases of great medical concern, particularly among…”
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Immune Evasion of SARS-CoV-2 Omicron Subvariants XBB.1.5, XBB.1.16 and EG.5.1 in a Cohort of Older Adults after ChAdOx1-S Vaccination and BA.4/5 Bivalent Booster by Machado, Rafael Rahal Guaragna, Candido, Érika Donizetti, Aguiar, Andressa Simoes, Chalup, Vanessa Nascimento, Sanches, Patricia Romão, Dorlass, Erick Gustavo, Amgarten, Deyvid Emanuel, Pinho, João Renato Rebello, Durigon, Edison Luiz, Oliveira, Danielle Bruna Leal

“…The recently emerged SARS-CoV-2 Omicron sublineages, including the BA.2-derived XBB.1.5 (Kraken), XBB.1.16 (Arcturus), and EG.5.1 (Eris), have accumulated…”
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Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease by Srinivasan, Vasundara, Brognaro, Hévila, Prabhu, Prince R., de Souza, Edmarcia Elisa, Günther, Sebastian, Reinke, Patrick Y. A., Lane, Thomas J., Ginn, Helen, Han, Huijong, Ewert, Wiebke, Sprenger, Janina, Koua, Faisal H. M., Falke, Sven, Werner, Nadine, Andaleeb, Hina, Ullah, Najeeb, Franca, Bruno Alves, Wang, Mengying, Barra, Angélica Luana C., Perbandt, Markus, Schwinzer, Martin, Schmidt, Christina, Brings, Lea, Lorenzen, Kristina, Schubert, Robin, Machado, Rafael Rahal Guaragna, Candido, Erika Donizette, Oliveira, Danielle Bruna Leal, Durigon, Edison Luiz, Niebling, Stephan, Garcia, Angelica Struve, Yefanov, Oleksandr, Lieske, Julia, Gelisio, Luca, Domaracky, Martin, Middendorf, Philipp, Groessler, Michael, Trost, Fabian, Galchenkova, Marina, Mashhour, Aida Rahmani, Saouane, Sofiane, Hakanpää, Johanna, Wolf, Markus, Alai, Maria Garcia, Turk, Dusan, Pearson, Arwen R., Chapman, Henry N., Hinrichs, Winfried, Wrenger, Carsten, Meents, Alke, Betzel, Christian

“…SARS-CoV-2 papain-like protease (PLpro) covers multiple functions. Beside the cysteine-protease activity, facilitating cleavage of the viral polypeptide chain,…”
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Validation of Serological Methods for COVID-19 and Retrospective Screening of Health Employees and Visitors to the São Paulo University Hospital, Brazil by Andreata-Santos, Robert, Machado, Rafael Rahal Guaragna, Alves, Rúbens Prince dos Santos, Sales, Natiely Silva, Soares, Camila Pereira, Rodrigues, Karine Bitencourt, Silva, Mariângela Oliveira, Favaro, Marianna Teixeira de Pinho, Rodrigues-Jesus, Mônica Josiane, Yamamoto, Márcio Massao, Andrade, Juliana Bannwart de, Fock, Ricardo Ambrósio, Margarido, Paulo Francisco Ramos, Carvalho, Cristiane Rodrigues Guzzo, Boscardin, Silvia Beatriz, Durigon, Edison Luiz, Ferreira, Luís C. S.

“…Reliable serological tests for the detection of SARS-CoV-2 antibodies among infected or vaccinated individuals are important for epidemiological and clinical…”
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Multisystem Inflammatory Syndrome Associated With COVID-19 With Neurologic Manifestations in a Child: A Brief Report by De Paulis, Milena, Oliveira, Danielle Bruna Leal, Vieira, Rodolfo P., Pinto, Isabella Coutinho, Machado, Rafael Rahal Guaragna, Cavalcanti, Mariana Pauferro, Soares, Camila Pereira, de Araujo, Ananda Medeiros Pereira, Araujo, Danielle Bastos, Bachi, Andre Luis Lacerda, Leal, Fabyano Bruno, Dorlass, Erick Gustavo, Gilio, Alfredo Elias, Durigon, Edison Luiz, Barreira, Eliane Roseli

“…Although first considered a benign infection, recent studies have disclosed severe and potentially lethal inflammatory manifestations of COVID-19 in children…”
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Zika virus seroprevalence in blood donors from the Northeastern region of São Paulo State, Brazil, between 2015 and 2017 by Slavov, Svetoslav Nanev, Guaragna Machado, Rafael Rahal, Ferreira, Alexander Rodrigo, Soares, Camila Pereira, Araujo, Danielle Bastos, Leal Oliveira, Danielle Bruna, Covas, Dimas Tadeu, Durigon, Edison Luiz, Kashima, Simone

“…Although primarily transmitted by Aedes aegypti mosquitos, Zika virus (ZIKV) can also be transmitted by blood transfusion, due to the fact that some of the…”
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Zika virus infection impairs synaptogenesis, induces neuroinflammation, and could be an environmental risk factor for autism spectrum disorder outcome by Ohki, Cristine Marie Yde, Benazzato, Cecília, van der Linden, Vanessa, França, Julia V., Toledo, Carmen M., Machado, Rafael Rahal Guaragna, Araujo, Danielle Bastos, Oliveira, Danielle Bruna Leal, Neris, Romulo S., Assunção-Miranda, Iranaia, de Oliveira Souza, Isis Nem, Nogueira, Clara O., Leite, Paulo Emilio Corrêa, van der Linden, Hélio, Figueiredo, Claudia P., Durigon, Edison Luiz, Clarke, Julia R., Russo, Fabiele Baldino, Beltrão-Braga, Patricia Cristina Baleeiro

“…Zika virus (ZIKV) infection was first associated with Central Nervous System (CNS) infections in Brazil in 2015, correlated with an increased number of…”
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