Search Results - "Machado, Rafael Pereira"
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Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates
Published in European journal of medicinal chemistry (10-03-2018)“…A new series of sixteen multifunctional N-benzyl-piperidine-aryl-acylhydrazones hybrid derivatives was synthesized and evaluated for multi-target activities…”
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The nicotinamide ruthenium(II) complex induces the production of reactive oxygen species (ROS), cell cycle arrest, and apoptosis in melanoma cells
Published in Polyhedron (01-02-2023)“…New complexes with the general formula [RuCl(NIC)(dppb)(X-bipy)]PF6 were prepared by exchanging the Cl-trans ligand to the phosphorus atom by Nicotinamide…”
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Journal Article