Search Results - "Machado, Michel Mansur"

Biological Safety Studies and Simultaneous Determination of Linagliptin and Synthetic Impurities by LC-PDA by Paim, Clésio S., Schapoval, Elfrides Eva Shermann, Paula, Fávero Reisdorfer, Malesuik, Marcelo Donadel, Machado, Michel Mansur, Oliveira, Luís Flávio Souza de, Ferreira, Flávio Dias, Duarte, Jonathaline Apollo, Heleno Ferreira, Raquel Balestri, Steppe, Martin

“…A stability-indicating LC method was developed for quantification of linagliptin (LGT) and three synthetic impurities. The method utilizes a Thermo Scientific®…”
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Phytochemistry Profile, Antimicrobial and Antitumor Potential of the Methanolic Extract of Tabernaemontana catharinensis A DC and Eragrostis plana NEES by da Rosa, Emanoeli, Stopiglia, Cheila Denise Ottonelli, Machado, Michel Mansur, Filho, Augusto Cezar Dotta, Soci, Ursula Paula Reno, Mendez, Andreas Sebastian Loureiro, Fernandes, Tiago, Oliveira, Edilamar Menezes de, Moreira, Cleci Menezes

“…Natural compounds that have the potential to act as antimicrobials and antitumors are a constant search in the field of pharmacotherapy. Eragrostis plana NEES…”
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Editorial: Toxicity mechanisms, exposure, toxicokinetic and risk assessment aspects of metals, toxic for animals and humans, Volume II by Zhu, Yanzhu, El-Demerdash, Fatma M, Yang, Xu, Boye, Alex, Machado, Michel Mansur, Li, Xinwei

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Editorial: Toxicity Mechanisms, Exposure, Toxicokinetic and Risk Assessment Aspects of Metals, Toxic for Animals and Humans by Zhu, Yanzhu, El-Demerdash, Fatma M, Boye, Alex, Machado, Michel Mansur, Li, Xinwei

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Sucralose causes non‐selective CD4 and CD8 lymphotoxicity via probable regulation of the MAPK8/APTX/EID1 genes: An in vitro/in silico study by Pasqualli, Thaís, Chaves, Pamella Eduardha, Pereira, Lavínia, Serpa, Élvio, Oliveira, Luís Flávio Souza, Machado, Michel Mansur

“…One of the most widely used sweeteners in the world is sucralose. With sweetening power 600 times greater than sucrose, its use grows among those who seek to…”
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Evaluation of basil extract ( Ocimum basilicum L.) on oxidative, anti-genotoxic and anti-inflammatory effects in human leukocytes cell cultures exposed to challenging agents by Güez, Camila Martins, Souza, Raul Oliveira de, Fischer, Paula, Leão, Maria Fernanda de Moura, Duarte, Jonathaline Apollo, Boligon, Aline Augusti, Athayde, Margareth Linde, Zuravski, Luísa, Oliveira, Luís Flávio Souza de, Machado, Michel Mansur

“…Ocimum is one of the most important genera of the Lamiaceae family. Several studies about basil and its popular use reveal many characteristics of the herb,…”
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Antioxidant activities of flavonol derivatives from the leaves and stem bark of Scutia buxifolia Reiss by Boligon, Aline Augusti, Pereira, Romaiana Picada, Feltrin, Andriéli Cassel, Machado, Michel Mansur, Janovik, Vanessa, Rocha, João Batista Teixeira, Athayde, Margareth Linde

“…This study evaluated the antioxidant activities in the leaves and stem bark fractions of Scutia buxifolia. Cerebral lipid peroxidation (TBARS) was induced by…”
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Phytochemical characterisation, antioxidant capacity, and in vitro toxicity of Richardia brasiliensis gomes crude extracts by Dornelles, Rafaela Castro, Guex, Camille Gaube, da Cruz, Ritiel Corrêa, de Lima, Rachel, Nogueira-Librelotto, Daniele Rubert, Ugalde, Gustavo de Andrade, Faccin, Henrique, Machado, Alencar Kolinski, Machado, Michel Mansur, Viana Silva, Carine, Manfron, Melânia Palermo, Bauermann, Liliane de Freitas

“…is a species used in folk medicine and rich in active compounds. In this study, the extracts were submitted to UHPLC-ESI-MS/MS analysis and total polyphenols,…”
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Tadalafil and Sildenafil illicit association: Stability- indicating HPLC method, photodegradation kinetic and toxicological studies by Pinto, Mayara Aramburú, Nicorena, Karine Favero, Machado, Michel Mansur, Oliveira, Luís Flávio Souza de, Paim, Clésio Soldateli, Silva, Fabiana Ernestina Barcellos da, Malesuik, Marcelo Donadel

“…Abstract The illicit market of counterfeit medicines containing sildenafil and tadalafil has been causing serious public health problems. Thus, further studies…”
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Protective effects of extracts and flavonoids isolated from Scutia buxifolia Reissek against chromosome damage in human lymphocytes exposed to hydrogen peroxide by Boligon, Aline Augusti, Sagrillo, Michele Rorato, Machado, Luiz Filipe, de Souza Filho, Olmiro, Machado, Michel Mansur, da Cruz, Ivana Beatrice Manica, Athayde, Margareth Linde

“…Flavonoids are claimed to protect against cardiovascular disease, certain forms of cancer and ageing, possibly by preventing initial DNA damage. Therefore, we…”
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Habitual Intake of Guaraná and Metabolic Morbidities: An Epidemiological Study of an Elderly Amazonian Population by Costa Krewer, Cristina, Ribeiro, Euler Esteves, Ribeiro, Ednéa Aguiar Maia, Moresco, Rafael Noal, Ugalde Marques da Rocha, Maria Izabel, Santos Montagner, Greice Franciele Feyl, Machado, Michel Mansur, Viegas, Karin, Brito, Elorídes, Cruz, Ivana Beatrice Mânica

“…The aim of the present study was to evaluate the associations of metabolic disorders and anthropometric and biochemical biomarkers of lipid, glucose and…”
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In vitro protective effect of Heterothalamus alienus against the Philodryas patagoniensis venom by Costa, Márcio Tavares, Etcheverria, Laura Lanes, da Rosa, Natiele Figueiredo, Carriço, Murilo Ricardo Sigal, Soares, Jefferson de Jesus, Denardin, Elton Luis Gasparotto, Machado, Michel Mansur, Folmer, Vanderlei, Farias, Fabiane Moreira

“…•Aqueous extract of H. alienus presents rutin, quercetin, and ferulic acid.•H. alienus extract show antioxidant potential.•This extract is nontoxic in Artemia…”
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Is tartrazine really safe? In silico and ex vivo toxicological studies in human leukocytes: a question of dose by Floriano, Jassana Moreira, Rosa, Emanoeli da, do Amaral, Queila Daiane Fonseca, Zuravski, Luísa, Chaves, Pamella Eduardha Espindola, Machado, Michel Mansur, de Oliveira, Luís Flávio Souza

“…The use of food colorings has a long-recorded history. Tartrazine (TRZ) is a dye that confers a lemon-yellow color to food and is widely used in the…”
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Antioxidant Activity and phytochemical composition of the leaves of Solanum guaraniticum A. St.-Hil by Zadra, Marina, Piana, Mariana, Brum, Thiele Faccim de, Boligon, Aline Augusti, Freitas, Robson Borba de, Machado, Michel Mansur, Stefanello, Sílvio Terra, Soares, Félix Alexandre Antunes, Athayde, Margareth Linde

“…Solanum guaraniticum is a shrub belonging to the Solanaceae family popularly known in Brazil as jurubeba or false-jurubeba. The aim of this study was to…”
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Novel Acaricidal Drug Fluazuron Causes Immunotoxicity via Selective Depletion of Lymphocytes T CD8 by Machado, Michel Mansur, Zuravski, Luísa, da Rosa, Emanoeli, Limberger, Jéssica Tamara, Chaves, Pamella Eduardha Espindola, Soares, Anelise Santos, Ribeiro, Juliana Gonçalves, Oliveira, Luís Flávio Souza de

“…Fluazuron is one of the newest veterinary antitick medicines. Belonging to the benzoylphenylureas group, its mechanism of action acts by the interference of…”
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Immunotoxicological Evaluation of Schinus molle L. (Anacardiaceae) Essential Oil in Lymphocytes and Macrophages by Machado, Michel Mansur, Oliveira, Luís Flávio Souza de, Bolignon, Aline, Schmitt, Elizandra Gomes, Rocha, Mariana Balhego, Quintana, Luciane Dias, Zambrano, Léa Augusta de Bairros, Duarte, Jonathaline Apollo, Anraku de Campos, Marli Matiko

“…Schinus molle L. is used to treat various diseases; however, the literature lacks information regarding its possible immunotoxic effects. The aim of the study…”
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Stability Study of Finasteride: Stability-Indicating LC Method, In Silico and LC-ESI-MS Analysis of Major Degradation Product, and an In Vitro Biological Safety Study by Reis, Rafael Henrique Dias, Paula, Fávero Reisdorfer, Machado, Michel Mansur, Duarte, Jonathaline Apollo, Oliveira, Luís Flávio Souza de, Paim, Clésio Soldateli, Malesuik, Marcelo Donadel

“…Abstract Stability studies of the pharmaceutically important compound finasteride were conducted in order to evaluate decomposition of the drug under forced…”
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CdCl2 has zero-order kinetic cellular influx and induces cytotoxicity and genotoxicity at low concentrations in human leukocytes in vitro by Fontoura dos Santos, Vanessa, Serpa, Elvio Adílio, Barcellos da Silva, Fabiana Ernestina, De Moraes Flores, Érico Marlon, Mansur Machado, Michel, Souza de Oliveira, Luís Flávio

“…Cadmium (Cd2+) is a nonessential heavy metal that possesses a high capacity of bioaccumulation and exhibits toxic characteristics even at low concentrations…”
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Antigenotoxic, antimutagenic and cytoprotective potential of Salvia hispanica L. seed extract on human leukocytes exposed to oxidative damage by Rosa, Emanoeli da, Amaral, Queila Daiane Fonseca do, Duarte, Jonathaline Apollo, Limberger, Jéssica Tamara, Chaves, Pamella Eduardha Espindola, Zuravski, Luísa, Oliveira, Luís Flávio Souza de, Machado, Michel Mansur

“…•Chia (Salvia hispanica) can reverse oxidative damage in DNA.•Chia (S. hispanica) can reduce the risk of mutagenesis caused by oxidative agents.•Chia improve…”
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Design, synthesis, and evaluation of novel 2-substituted 1,4-benzenediol library as antimicrobial agents against clinically relevant pathogens by Dalla Lana, Daiane Flores, Batista, Bruna Gerardon, da Rosa Machado, Gabriella, Teixeira, Mário Lettieri, de Oliveira, Luís Flávio Souza, Machado, Michel Mansur, de Andrade, Saulo Fernandes, Lopes, William, Vainstein, Marilene Henning, de Abreu Lima, Alejandro Peixoto, Pandolfi, Enrique, Silva, Edilma Elayne, Fuentefria, Alexandre Meneghello, Silveira, Gustavo Pozza

“…[Display omitted] Development of new antimicrobial agents, capable of combating resistant and multidrug-resistant fungal and bacterial clinical strains, is…”
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