Search Results - "Machado, Flávia G."

Regression of glomerular injury by losartan in experimental diabetic nephropathy by Teles, Flávio, Machado, Flávia G., Ventura, Bianca H., Malheiros, Denise M.A.C., Fujihara, Clarice K., Silva, Luís F.F., Zatz, Roberto

“…Many features of chronic kidney disease may be reversed, but it is unclear whether advanced lesions, such as adhesions of sclerotic glomerular tufts to…”
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Gli1 + Pericyte Loss Induces Capillary Rarefaction and Proximal Tubular Injury by Kramann, Rafael, Wongboonsin, Janewit, Chang-Panesso, Monica, Machado, Flavia G, Humphreys, Benjamin D

“…Peritubular capillary rarefaction is hypothesized to contribute to the increased risk of future CKD after AKI. Here, we directly tested the role of Gli1 kidney…”
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A conditionally immortalized Gli1-positive kidney mesenchymal cell line models myofibroblast transition by Ó hAinmhire, Eoghainín, Wu, Haojia, Muto, Yoshiharu, Donnelly, Erinn L, Machado, Flavia G, Fan, Lucy X, Chang-Panesso, Monica, Humphreys, Benjamin D

“…Glioma-associated oncogene homolog-1 (Gli1)-positive resident mesenchymal stem cell-like cells are the predominant source of kidney myofibroblasts in fibrosis,…”
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Adventitial MSC-like Cells Are Progenitors of Vascular Smooth Muscle Cells and Drive Vascular Calcification in Chronic Kidney Disease by Kramann, Rafael, Goettsch, Claudia, Wongboonsin, Janewit, Iwata, Hiroshi, Schneider, Rebekka K., Kuppe, Christoph, Kaesler, Nadine, Chang-Panesso, Monica, Machado, Flavia G., Gratwohl, Susannah, Madhurima, Kaushal, Hutcheson, Joshua D., Jain, Sanjay, Aikawa, Elena, Humphreys, Benjamin D.

“…Mesenchymal stem cell (MSC)-like cells reside in the vascular wall, but their role in vascular regeneration and disease is poorly understood. Here, we show…”
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Innate And Adaptive Immunity are Progressively Activated in Parallel with Renal Injury in the 5/6 Renal Ablation Model by Fanelli, Camilla, Arias, Simone C. A., Machado, Flavia G., Okuma, Jessica K., Malheiros, Denise M. A. C., Azevedo, Hatylas, Moreira-Filho, Carlos A., Camara, Niels O. S., Fujihara, Clarice K., Zatz, Roberto

“…The mechanisms triggering renal inflammation in chronic kidney disease (CKD) are unclear. We performed a detailed analysis of the time course of innate and…”
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Chronic VEGF blockade worsens glomerular injury in the remnant kidney model by Machado, Flavia G, Kuriki, Patrícia Semedo, Fujihara, Clarice K, Fanelli, Camilla, Arias, Simone C A, Malheiros, Denise M A C, Camara, Niels O S, Zatz, Roberto

“…VEGF inhibition can promote renal vascular and parenchymal injury, causing proteinuria, hypertension and thrombotic microangiopathy. The mechanisms underlying…”
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Programmed hypertension in rats treated with a NF-κB inhibitor during nephrogenesis: renal mechanisms by Canale, Daniele, Rodrigues, Mariliza V, Ferreira, Daniele N, Machado, Flavia G, Veras, Mariana M, Malheiros, Denise M A C, Krieger, José E, Fujihara, Clarice K, Venturini, Gabriela, Zatz, Roberto

“…Suppression of the renin-angiotensin system (RAS) during murine lactation causes progressive renal injury, indicating a physiological action of angiotensin II…”
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Meis1 is specifically upregulated in kidney myofibroblasts during aging and injury but is not required for kidney homeostasis or fibrotic response by Chang-Panesso, Monica, Kadyrov, Farid F, Machado, Flavia G, Kumar, Ashish, Humphreys, Benjamin D

“…The homeobox transcription factor Meis1 is required for mammalian development, and its overexpression plays a role in tumorigenesis, especially leukemia. Meis1…”
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Aging Alters Microenvironmental Cues for Gli1+ Myofibroblast Progenitors to Promote Tissue Remodeling in the Kidneys: FR-PO992 by Muto, Yoshiharu, hAinmhire, Eoghainín Ó, Machado, Flavia G., Humphreys, Benjamin D.

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Sodium phosphate cotransporters in intestinal absorption of phosphorus in uremic rats by Aniteli, Tatiana Martins, Machado, Flavia G., de Souza, Renata A. M., Dominguez, Wagner V., Castelucci, Patrícia, Jorgetti, Vanda

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