Search Results - "Machado, Ben"
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The African Turquoise Killifish Genome Provides Insights into Evolution and Genetic Architecture of Lifespan
Published in Cell (03-12-2015)“…Lifespan is a remarkably diverse trait ranging from a few days to several hundred years in nature, but the mechanisms underlying the evolution of lifespan…”
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Crude Oil Impairs Cardiac Excitation-Contraction Coupling in Fish
Published in Science (American Association for the Advancement of Science) (14-02-2014)“…Crude oil is known to disrupt cardiac function in fish embryos. Large oil spills, such as the Deepwater Horizon (DWH) disaster that occurred in 2010 in the…”
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Tissue-specific landscape of protein aggregation and quality control in an aging vertebrate
Published in Developmental cell (22-07-2024)“…Protein aggregation is a hallmark of age-related neurodegeneration. Yet, aggregation during normal aging and in tissues other than the brain is poorly…”
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A Platform for Rapid Exploration of Aging and Diseases in a Naturally Short-Lived Vertebrate
Published in Cell (26-02-2015)“…Aging is a complex process that affects multiple organs. Modeling aging and age-related diseases in the lab is challenging because classical vertebrate models…”
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Identification of protein aggregates in the aging vertebrate brain with prion-like and phase-separation properties
Published in Cell reports (Cambridge) (25-06-2024)“…Protein aggregation, which can sometimes spread in a prion-like manner, is a hallmark of neurodegenerative diseases. However, whether prion-like aggregates…”
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Salinity tolerance in diapausing embryos of the annual killifish Austrofundulus limnaeus is supported by exceptionally low water and ion permeability
Published in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology (01-10-2007)“…The annual killifish Austrofundulus limnaeus inhabits rainwater pools in the Maracaibo basin of Venezuela. This species persists in ephemeral habitats by…”
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Crude Oil Impairs Cardiac Excitation-Contraction Coupling in Fish
Published in Biophysical journal (28-01-2014)Get full text
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