Search Results - "Mach, Phillip M"

Proteomic Characterization of Dermal Interstitial Fluid Extracted Using a Novel Microneedle-Assisted Technique by Tran, Bao Quoc, Miller, Philip R, Taylor, Robert M, Boyd, Gabrielle, Mach, Phillip M, Rosenzweig, C. Nicole, Baca, Justin T, Polsky, Ronen, Glaros, Trevor

“…As wearable fitness devices have gained commercial acceptance, interest in real-time monitoring of an individual’s physiological status using noninvasive…”
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Vehicle-Mounted Portable Mass Spectrometry System for the Covert Detection via Spatial Analysis of Clandestine Methamphetamine Laboratories by Mach, Phillip M, McBride, Ethan M, Sasiene, Zachary J, Brigance, Katie R, Kennard, Shelia K, Wright, Kenneth C, Verbeck, Guido F

“…The ability to detect atmospheric effluent from clandestine methamphetamine manufacture is a useful tool for law enforcement. A membrane inlet mass…”
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Discovery of treatment for nerve agents targeting a new metabolic pathway by Glaros, Trevor, Dhummakupt, Elizabeth S., Rizzo, Gabrielle M., McBride, Ethan, Carmany, Daniel O., Wright, Linnzi K. M., Forster, Jeffry S., Renner, Julie A., Moretz, Ruth W., Dorsey, Russell, Marten, Mark R., Huso, Walker, Doan, Alexander, Dorsey, Carrie D., Phillips, Christopher, Benton, Bernard, Mach, Phillip M.

“…The inhibition of acetylcholinesterase is regarded as the primary toxic mechanism of action for chemical warfare agents. Recently, there have been numerous…”
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The Burkholderia pseudomallei hmqA-G Locus Mediates Competitive Fitness against Environmental Gram-Positive Bacteria by Mou, Sherry, Jenkins, Conor C, Okaro, Udoka, Dhummakupt, Elizabeth S, Mach, Phillip M, DeShazer, David

“…Burkholderia pseudomallei is an opportunistic pathogen that is responsible for the disease melioidosis in humans and animals. The microbe is a tier 1 select…”
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Pressure-Sensitive Adhesive Combined with Paper Spray Mass Spectrometry for Low-Cost Collection and Analysis of Drug Residues by Nguyen, Chau Bao, Wichert, William R. A, Carmany, Daniel O, McBride, Ethan M, Mach, Phillip M, Dhummakupt, Elizabeth S, Glaros, Trevor, Manicke, Nicholas E

“…Illicit drug use causes over half a million deaths worldwide every year. Drugs of abuse are commonly smuggled through customs and border checkpoints and,…”
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Proteomic Characterization of Immunoglobulin Content in Dermal Interstitial Fluid by Arévalo, Maria T, Rizzo, Gabrielle M, Polsky, Ronen, Glaros, Trevor, Mach, Phillip M

“…Microneedles have been demonstrated to be a minimally invasive technique for sampling dermal interstitial fluid (ISF). Shotgun quantitative proteomics has…”
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The Addition of Transcriptomics to the Bead-Enabled Accelerated Monophasic Multi-Omics Method: A Step toward Universal Sample Preparation by Breidenbach, Joshua D., Rivera, Emilio S., Harvey, Tara, Mikolitis, Abigale S., Tseng, Chi Yen, Sanders, Claire K., Solomon, Emilia, Gleasner, Cheryl D., Thornhill, M. Grace, Luchini, Kes A., McBride, Ethan M., Blackwell, Brett R., LeBrun, Erick S., Mach, Phillip M., Glaros, Trevor G.

“…Omics-based measurements enable the study of biomolecules in a high-throughput fashion, leading to the characterization and quantification of biological…”
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Normalization of organ-on-a-Chip samples for mass spectrometry based proteomics and metabolomics via Dansylation-based assay by Gallagher, Erin M., Rizzo, Gabrielle M., Dorsey, Russell, Dhummakupt, Elizabeth S., Moran, Theodore S., Mach, Phillip M., Jenkins, Conor C.

“…Mass spectrometry based ‘omics pairs well with organ-on-a-chip-based investigations, which often have limited cellular material for sampling. However, a common…”
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Multidimensional mass profiles increase confidence in bacterial identification when using low-resolution mass spectrometers by Sasiene, Zachary J, LeBrun, Erick S, Velappan, Nileena, Anderson, Austin R, Patterson, Nathan H, Dufresne, Martin, Farrow, Melissa A, Norris, Jeremy L, Caprioli, Richard M, Mach, Phillip M, McBride, Ethan M, Glaros, Trevor G

“…Field-forward analytical technologies, such as portable mass spectrometry (MS), enable essential capabilities for real-time monitoring and point-of-care…”
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Feature-agnostic metabolomics for determining effective subcytotoxic doses of common pesticides in human cells by Rivera, Emilio S, LeBrun, Erick S, Breidenbach, Joshua D, Solomon, Emilia, Sanders, Claire K, Harvey, Tara, Tseng, Chi Yen, Thornhill, M Grace, Blackwell, Brett R, McBride, Ethan M, Luchini, Kes A, Alvarez, Marc, Williams, Robert F, Norris, Jeremy L, Mach, Phillip M, Glaros, Trevor G

“…Abstract Although classical molecular biology assays can provide a measure of cellular response to chemical challenges, they rely on a single biological…”
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Detection of Protein Toxin Simulants from Contaminated Surfaces by Paper Spray Mass Spectrometry by Wichert, William R. A., Dhummakupt, Elizabeth S., Zhang, Chengsen, Mach, Phillip M., Bernhards, Robert C., Glaros, Trevor, Manicke, Nicholas E.

“…Proteinaceous toxins are harmful proteins derived from plants, bacteria, and other natural sources. They pose a risk to human health due to infection and also…”
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Direct Analysis of Aerosolized Chemical Warfare Simulants Captured on a Modified Glass-Based Substrate by “Paper-Spray” Ionization by Dhummakupt, Elizabeth S, Mach, Phillip M, Carmany, Daniel, Demond, Paul S, Moran, Theodore S, Connell, Theresa, Wylie, Harold S, Manicke, Nicholas E, Nilles, J. Michael, Glaros, Trevor

“…Paper spray ionization mass spectrometry offers a rapid alternative platform requiring no sample preparation. Aerosolized chemical warfare agent (CWA)…”
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Temporal variation in groundwater quality in the Permian Basin of Texas, a region of increasing unconventional oil and gas development by Hildenbrand, Zacariah L., Carlton, Doug D., Fontenot, Brian E., Meik, Jesse M., Walton, Jayme L., Thacker, Jonathan B., Korlie, Stephanie, Shelor, C. Phillip, Kadjo, Akinde F., Clark, Adelaide, Usenko, Sascha, Hamilton, Jason S., Mach, Phillip M., Verbeck, Guido F., Hudak, Paul, Schug, Kevin A.

“…The recent expansion of natural gas and oil extraction using unconventional oil and gas development (UD) practices such as horizontal drilling and hydraulic…”
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Metal–Organic Framework Modified Glass Substrate for Analysis of Highly Volatile Chemical Warfare Agents by Paper Spray Mass Spectrometry by Dhummakupt, Elizabeth S, Carmany, Daniel O, Mach, Phillip M, Tovar, Trenton M, Ploskonka, Ann M, Demond, Paul S, DeCoste, Jared B, Glaros, Trevor

“…Paper spray mass spectrometry has been shown to successfully analyze chemical warfare agent (CWA) simulants. However, due to the volatility differences between…”
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Point source attribution of ambient contamination events near unconventional oil and gas development by Hildenbrand, Zacariah L., Mach, Phillip M., McBride, Ethan M., Dorreyatim, M. Navid, Taylor, Josh T., Carlton, Doug D., Meik, Jesse M., Fontenot, Brian E., Wright, Kenneth C., Schug, Kevin A., Verbeck, Guido F.

“…We present an analysis of ambient benzene, toluene, and xylene isomers in the Eagle Ford shale region of southern Texas. In situ air quality measurements using…”
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Rapid liquid chromatography tandem mass spectrometry method for targeted quantitation of human performance metabolites in saliva by McBride, Ethan M., Lawrence, Richard J., McGee, Kirstin, Mach, Phillip M., Demond, Paul S., Busch, Michael W., Ramsay, John W., Hussey, Erika K., Glaros, Trevor, Dhummakupt, Elizabeth S.

“…•Targeted method for quantitating eight analytes of human performance in saliva.•Simple sample preparation procedure allows for nearly 100% analyte…”
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Omics potential of in vitro skin models for radiation exposure by Akh, Leyla A., Ishak, Mohammad O., Harris, Jennifer F., Glaros, Trevor G., Sasiene, Zachary J., Mach, Phillip M., Lilley, Laura M., McBride, Ethan M.

“…There is a growing need to uncover biomarkers of ionizing radiation exposure that leads to a better understanding of how exposures take place, including dose…”
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On‐substrate derivatization for detection of highly volatile G‐series chemical warfare agents via paper spray mass spectrometry by Mach, Phillip M., Dhummakupt, Elizabeth S., Carmany, Daniel O., McBride, Ethan M., Busch, Michael W., Demond, Paul S., Rizzo, Gabrielle M., Hollinshead, Donna E., Glaros, Trevor

“…Rationale The analysis of chemical warfare agents (CWAs) from ambient atmosphere presents an analytical challenge due to their ease of degradation and…”
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Development of Multi-Membrane Near-Infrared Diode Mass Spectrometer for Field Analysis of Aromatic Hydrocarbons by Mach, Phillip M., Wright, Kenneth C., Verbeck, Guido F.

“…Membrane Inlet Mass Spectrometry (MIMS) is a technique that incorporates a semi-permeable membrane selective for differing organic molecules and chemistries…”
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On-substrate Enzymatic Reaction to Determine Acetylcholinesterase Activity in Whole Blood by Paper Spray Mass Spectrometry by Carmany, Daniel O., Mach, Phillip M., Rizzo, Gabrielle M., Dhummakupt, Elizabeth S., McBride, Ethan M., Sekowski, Jennifer W., Benton, Bernard, Demond, Paul S., Busch, Michael W., Glaros, Trevor

“…Currently, all assays measuring acetylcholinesterase (AChE) activity following a suspected nerve agent exposure leverage methodologies that fail to identify…”
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