Search Results - "Macete, Eusebio"
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Efficacy and safety of the RTS,S/AS01 malaria vaccine during 18 months after vaccination: a phase 3 randomized, controlled trial in children and young infants at 11 African sites
Published in PLoS medicine (01-07-2014)“…A malaria vaccine could be an important addition to current control strategies. We report the safety and vaccine efficacy (VE) of the RTS,S/AS01 vaccine during…”
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A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants
Published in The New England journal of medicine (13-12-2012)“…In this ongoing phase 3 study of over 6000 infants (6 to 12 weeks of age) at 11 centers in Africa, the RTS,S/AS01 vaccine had 30% efficacy in preventing the…”
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First-trimester artemisinin derivatives and quinine treatments and the risk of adverse pregnancy outcomes in Africa and Asia: A meta-analysis of observational studies
Published in PLoS medicine (02-05-2017)“…Animal embryotoxicity data, and the scarcity of safety data in human pregnancies, have prevented artemisinin derivatives from being recommended for malaria…”
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First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children
Published in The New England journal of medicine (17-11-2011)“…Each year, about 225 million persons have malaria, with some 781,000 associated deaths. In a preliminary report of a phase 3 trial in African children, the…”
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Detecting temporal and spatial malaria patterns from first antenatal care visits
Published in Nature communications (06-07-2023)“…Pregnant women attending first antenatal care (ANC) visits represent a promising malaria surveillance target in Sub-Saharan Africa. We assessed the…”
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Factors associated with use of insecticide-treated net for malaria prevention in Manica District, Mozambique: a community-based cross-sectional survey
Published in Malaria journal (27-04-2021)“…Insecticide-treated net (ITN) use is crucial for preventing malaria infection. Despite significant improvements in ITN access and use over the past two…”
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Genomic malaria surveillance of antenatal care users detects reduced transmission following elimination interventions in Mozambique
Published in Nature communications (16-03-2024)“…Routine sampling of pregnant women at first antenatal care (ANC) visits could make Plasmodium falciparum genomic surveillance more cost-efficient and…”
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Health impacts of industrial mining on surrounding communities: Local perspectives from three sub-Saharan African countries
Published in PloS one (04-06-2021)“…Industrial mining projects can play an important role in global sustainable development if associated health risks are minimised and opportunities maximised…”
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Setting the scene and generating evidence for malaria elimination in Southern Mozambique
Published in Malaria journal (06-06-2019)“…Mozambique has historically been one of the countries with the highest malaria burden in the world. Starting in the 1960s, malaria control efforts were…”
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Changing Trends in P. falciparum Burden, Immunity, and Disease in Pregnancy
Published in The New England journal of medicine (22-10-2015)“…Great strides have been made in malaria control, but loss of partial immunity may lead to more-severe disease when infection occurs. In this study of pregnant…”
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A multiphase program for malaria elimination in southern Mozambique (the Magude project): A before-after study
Published in PLoS medicine (01-08-2020)“…[...]the south of Mozambique has historically experienced unsuccessful malaria control and elimination attempts using mainly IRS in the 1960s during the Global…”
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Etiology of diarrhea in children younger than 5 years of age admitted in a rural hospital of southern Mozambique
Published in The American journal of tropical medicine and hygiene (01-03-2007)“…Diarrhea is one of the main causes of morbidity and mortality among children in sub-Saharan Africa and one of the main causes of hospital admissions in rural…”
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Validity of a minimally invasive autopsy tool for cause of death determination in pediatric deaths in Mozambique: An observational study
Published in PLoS medicine (20-06-2017)“…In recent decades, the world has witnessed unprecedented progress in child survival. However, our knowledge of what is killing nearly 6 million children…”
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Gravidity and malaria trends interact to modify P. falciparum densities and detectability in pregnancy: a 3-year prospective multi-site observational study
Published in BMC medicine (15-11-2022)“…Abstract Background Low-density Plasmodium falciparum infections prevail in low transmission settings, where immunity is expected to be minimal, suggesting an…”
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Escherichia coli ST131 clones harbouring AggR and AAF/V fimbriae causing bacteremia in Mozambican children: Emergence of new variant of fimH27 subclone
Published in PLoS neglected tropical diseases (01-05-2020)“…Multidrug-resistant Escherichia coli ST131 fimH30 responsible for extra-intestinal pathogenic (ExPEC) infections is globally distributed. However, the…”
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Validity of a Minimally Invasive Autopsy for Cause of Death Determination in Adults in Mozambique: An Observational Study
Published in PLoS medicine (22-11-2016)“…There is an urgent need to identify tools able to provide reliable information on the cause of death in low-income regions, since current methods (verbal…”
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Validity of a minimally invasive autopsy for cause of death determination in stillborn babies and neonates in Mozambique: An observational study
Published in PLoS medicine (20-06-2017)“…Over 5 million stillbirths and neonatal deaths occur annually. Limited and imprecise information on the cause of these deaths hampers progress in achieving…”
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A 10 year study of the cause of death in children under 15 years in Manhiça, Mozambique
Published in BMC public health (24-02-2009)“…Approximately 46 million of the estimated 60 million deaths that occur in the world each year take place in developing countries. Further, this mortality is…”
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Molecular evidence for the localization of Plasmodium falciparum immature gametocytes in bone marrow
Published in Blood (13-02-2014)“…Plasmodium falciparum immature gametocytes are not observed in peripheral blood. However, gametocyte stages in organs such as bone marrow have never been…”
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The Community-Level Interventions for Pre-eclampsia (CLIP) cluster randomised trials in Mozambique, Pakistan, and India: an individual participant-level meta-analysis
Published in The Lancet (British edition) (22-08-2020)“…To overcome the three delays in triage, transport and treatment that underlie adverse pregnancy outcomes, we aimed to reduce all-cause adverse outcomes with…”
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