Search Results - "Macejová, Dana"

The phytoestrogenic Cyclopia extract, SM6Met, increases median tumor free survival and reduces tumor mass and volume in chemically induced rat mammary gland carcinogenesis by Visser, Koch, Zierau, Oliver, Macejová, Dana, Goerl, Florian, Muders, Michael, Baretton, Gustavo B., Vollmer, Günter, Louw, Ann

“…•SM6Met, acts as a chemopreventative agent against MNU-induced rat mammary gland carcinogenesis.•SM6Met increases tumor latency by 7 days and median tumor free…”
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Relationship between histology, development and tumorigenesis of mammary gland in female rat by LÍŠKA, Ján, BRTKO, Július, DUBOVICKÝ, Michal, MACEJOVÁ, Dana, KISSOVÁ, Viktória, POLÁK, Štefan, UJHÁZY, Eduard

“…The mammary gland is a dynamic organ that undergoes structural and functional changes associated with growth, reproduction, and post-menopausal regression. The…”
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Nuclear receptors - target molecules for isoflavones in cancer chemoprevention by Bialešová, Lucia, Brtko, Július, Lenko, Vladimír, Macejová, Dana

“…Breast cancer is the most occurring type of cancer among women. In Slovakia, there are yearly diagnosed about 1900 new cases of this disease. Breast cancer…”
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MNU-induced mammary gland carcinogenesis: Chemopreventive and therapeutic effects of vitamin D and Seocalcitol on selected regulatory vitamin D receptor pathways by Macejová, Dana, Ondková, Slavomíra, Jakubíková, Lucia, Mlynarčíková, Alžbeta, Scsuková, Soňa, Liška, Ján, Brtko, Július

“…► Vitamin D 3 and Seocalcitol as tools in prevention and therapy of mammary gland cancer. ► Seocalcitol markedly prolongs tumor latency. ► MicroPET analysis…”
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Combined treatment of P-gp-positive L1210/VCR cells by verapamil and all- trans retinoic acid induces down-regulation of P-glycoprotein expression and transport activity by Sulová, Zdena, Macejová, Dana, Šereš, Mário, Sedlák, Ján, Brtko, Július, Breier, Albert

“…The development of the most common multidrug resistance (MDR) phenotype associated with a massive overexpression of P-glycoprotein (P-gp) in neoplastic cells…”
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Different mRNA expression profiling of nuclear retinoid, thyroid, estrogen and PPARgamma receptors, their coregulators and selected genes in rat liver and spleen in response to short-term in vivo administration of 13- cis retinoic acid by Macejová, Dana, Križanová, Oľga, Brtko, Július

“…Retinoic acids (RAs) and also their analogs (synthetic retinoids and rexinoids) have been regarded as major therapeutic and/or chemopreventive agents and can…”
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Expression of selected nuclear receptors in human epithelial ovarian cell line Caov3 exposed to bisphenol derivatives by Mlynarcikova, Alzbeta Bujnakova, Macejova, Dana, Scsukova, Sona

“…Bisphenol A (BPA) is an indispensable industrial chemical. However, as a proven endocrine disruptor, it may be associated with several health disturbances,…”
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Malignant Triton tumour exhibits a complete expression pattern of nuclear retinoid and rexinoid receptor subtypes by Brtko, Július, Sejnová, Daniela, Ondková, Slavomíra, Macejová, Dana

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A comparative study of protein patterns of human estrogen receptor positive (MCF-7) and negative (MDA-MB-231) breast cancer cell lines by Flodrova, Dana, Toporova, Lucia, Macejova, Dana, Lastovickova, Marketa, Brtko, Julius, Bobalova, Janette

“…In the present study, we analyzed the cell lysates of human tumour cell lines representing two major clinically different types of breast cancer. Our main goal…”
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The role of retinoic acid receptors and their cognate ligands in reproduction in a context of triorganotin based endocrine disrupting chemicals by Macejova, Dana, Toporova, L., Brtko, J.

“…Retinoic acid (RA), an active form of vitamin A, regulates the embryonic development, male and female reproduction and induces important effects on the cell…”
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mRNA expression pattern of retinoic acid and retinoid X nuclear receptor subtypes in human thyroid papillary carcinoma by MACEJOVÁ, DANA, GALBAVÝ, ŠTEFAN, PODOBA, JÁN, BIALEŠOVÁ, LUCIA, BRTKO, JÚLIUS

“…Retinoids have shown potential for the inhibition of tumour growth and progression. The objective of this study was to investigate retinoic acid nuclear…”
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Effects of biologically active tributyl-/triphenyl-organometal ligands of retinoid X receptors in human breast cancer cell line by Macejová, Dana, Bialešová, Lucia, Toporová, Lucia, Brtko, Július

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Changes in retinoic acid receptor status, 5′-deiodinase activity and neuroendocrine response to voluntary wheel running by Ondkova, Slavomira, Bakos, Jan, Macejova, Dana, Jezova, Daniela, Brtko, Julius

“…Abstract Little information is available on the involvement of retinoic acid in processes related to physical activity. The aim of this study was to test the…”
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Selenium - its role in physiology and endocrinology and as organoselenium compounds in oncology: A minireview by Brtko, Julius, Podoba, Jan, Macejova, Dana

“…The present minireview traces the road leading to discovery of selenium, formerly appointed as a toxic element that became later a bioelement, which is…”
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Triphenyltin isoselenocyanate: a novel nuclear retinoid X receptor ligand with antiproliferative and cytotoxic properties in cell lines derived from human breast cancer by Macejova, Dana, Kollar, Jakub, Bobal, Pavel, Otevrel, Jan, Schuster, Daniela, Brtko, Julius

“…Several commercially available triorganotin compounds were previously found to function as agonist ligands for nuclear retinoid X receptor (RXR) molecules…”
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Radioligand binding assay for accurate determination of nuclear retinoid X receptors: A case of triorganotin endocrine disrupting ligands by Toporova, Lucia, Macejova, Dana, Brtko, Julius

“…[Display omitted] •Novel radioligand binding assay for accurate determination of retinoid X receptors binding capabilities.•Optimal conditions for 9-cis…”
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Histological evaluation of rat mammary tumours after treatment with retinoic acid analogues — phytol, TTNPB and vitamin D3 analogue seocalcitol by Líška, Ján, Ondková, Slavomíra, Macejová, Dana, Brtko, Július

“…The effects of retinoic acid analogue — phytol (precursor of retinoic X receptors ligand), TTNPB (retinoic acid receptor agonist) and seocalcitol (EB1089,…”
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Expression, protein stability and transcriptional activity of retinoic acid receptors are affected by microtubules interfering agents and all- trans-retinoic acid in primary rat hepatocytes by Dvořák, Zdeněk, Vrzal, Radim, Ulrichová, Jitka, Macejová, Dana, Ondková, Slavomíra, Brtko, Július

“…Cellular signaling by glucocorticoid receptor and aryl hydrocarbon receptor is restricted by microtubules interfering agents (MIAs). This leads to…”
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Chronic propranolol treatment moderately attenuated development of N-methyl-N-nitrosourea-induced mammary carcinoma in female rats by Tibensky, Miroslav, Cernackova, Alena, Horvathova, Lubica, Macejova, Dana, Tillinger, Andrej, Mravec, Boris

“…The sympathetic nervous system participates in the development and progression of several cancer types and this effect is mediated mainly via β-adrenergic…”
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Down-regulation of vimentin by triorganotin isothiocyanates—nuclear retinoid X receptor agonists: A proteomic approach by Strouhalova, Dana, Macejova, Dana, Mosna, Barbora, Bobal, Pavel, Otevrel, Jan, Lastovickova, Marketa, Brtko, Julius, Bobalova, Janette

“…•Treatment of MDA-MB-231 cells with triorganotin isothiocyanates and all-trans retinoic acid.•Application of proteomic approach based on bottom-up strategy and…”
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