Search Results - "Macejak, D G"

Inhibition of hepatitis C virus (HCV)‐RNA–dependent translation and replication of a chimeric HCV poliovirus using synthetic stabilized ribozymes by Macejak, Dennis G., Jensen, Kristi L., Jamison, Sharon F., Domenico, Kristal, Roberts, Elisabeth C., Chaudhary, Nilabh, von Carlowitz, Ira, Bellon, Laurent, Tong, Myron J., Conrad, Andrew, Pavco, Pamela A., Blatt, Lawrence M.

“…Ribozymes are catalytic RNA molecules that can be designed to cleave specific RNA sequences. To investigate the potential use of synthetic stabilized ribozymes…”
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Association of heat shock protein 70 with enterovirus capsid precursor P1 in infected human cells by MACEJAK, D. G, SARNOW, P

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Enhanced antiviral effect in cell culture of type 1 interferon and ribozymes targeting HCV RNA by Macejak, D. G., Jensen, K. L., Pavco, P. A., Phipps, K. M., Heinz, B. A., Colacino, J. M., Blatt, L. M.

“…We have recently shown that the replication of an HCV‐poliovirus (PV) chimera that is dependent upon the hepatitis C virus (HCV) 5′ untranslated region (UTR)…”
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Characterization of nuclease-resistant ribozymes directed against hepatitis B virus RNA by Morrissey, D. V., Lee, P. A., Johnson, D. A., Overly, S. L., McSwiggen, J. A., Beigelman, L., Mokler, V. R., Maloney, L., Vargeese, C., Bowman, K., O'Brien, J. T., Shaffer, C. S., Conrad, A., Schmid, P., Morrey, J. D., Macejak, D. G., Pavco, P. A., Blatt, L. M.

“…Hepatitis B virus (HBV) is responsible for > 350 million cases of chronic hepatitis B worldwide and 1.2 million deaths each year. To explore the use of…”
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Internal initiation of translation mediated by the 5′ leader of a cellular mRNA by Macejak, Dennis G, Sarnow, Peter

“…A Robosome-scanning model has been proposed to explain the initiation of eukaryotic messenger RNAs in which binding of the 43S ternary ribosomal subunit near…”
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Association of HSP70 with the adenovirus type 5 fiber protein in infected HEp-2 cells by Macejak, D G, Luftig, R B

“…Although maximal synthesis of HSP70 is induced early (6-12 hr) after adenovirus type 5 (Ad5) infection of HEp-2 or HeLa cells, the total amount of HSP70…”
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Stabilization of actin filaments at early times after adenovirus infection and in heat-shocked cells by Macejak, D G, Luftig, R B

“…Human cells (HEp-2) infected with adenovirus type 5 (Ad5) at early times (5-7 h) after infection exhibit stabilization of the filamentous actin network against…”
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Adenovirus-mediated expression of a ribozyme to c-myb mRNA inhibits smooth muscle cell proliferation and neointima formation in vivo by Macejak, D G, Lin, H, Webb, S, Chase, J, Jensen, K, Jarvis, T C, Leiden, J M, Couture, L

“…Smooth muscle cell (SMC) proliferation is an important component of restenosis in response to injury after balloon angioplasty. Inhibition of proliferation in…”
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Translational regulation of the immunoglobulin heavy-chain binding protein mRNA by Macejak, D G, Sarnow, P

“…Translation of the mRNA encoding the immunoglobulin heavy-chain binding protein (BiP) is enhanced in poliovirus-infected cells at a time when translation of…”
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High-precision gene expression analysis of immunosuppressive agents in human whole blood by Tryon, Victor V., Cheronis, John C., Trollinger, David B., Bankaitis-Davis, Danute, Storm, Kathleen, Zuzack, John S., Zhan, Min, Macejak, Dennis G., Bevilacqua, Michael P.

“…Analysis of gene expression is emerging as a valuable tool in drug discovery. Using a gene expression system involving high‐precision quantitative PCR, two…”
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