Search Results - "Macedo, M. Fatima"
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Monocyte antigen-presenting capacity to iNKT cells is influenced by the blood collection conditions
Published in Journal of immunological methods (01-02-2023)“…It is widely accepted that different blood collection conditions, including anticoagulants, influence leukocyte phenotype and function. Buffy Coats originated…”
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Inherited Metabolic Disorders: From Bench to Bedside
Published in Biomedicines (01-01-2024)“…Inherited metabolic disorders (IMDs), commonly referred to as inborn errors of metabolism, represent a spectrum of disorders with a defined (or presumed)…”
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Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin
Published in Nature immunology (01-12-2019)“…Invariant natural killer T (iNKT) cells recognize activating self and microbial lipids presented by CD1d. CD1d can also bind non-activating lipids, such as…”
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Buffy Coat Processing Impacts on Monocytes' Capacity to Present Lipid Antigens
Published in Biomedicines (01-03-2023)“…Buffy Coats, generated from a blood donor's whole blood bag unit, are commonly used in biomedical research as a source of leukocytes due to the high number of…”
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Leukocyte Imbalances in Mucopolysaccharidoses Patients
Published in Biomedicines (13-06-2023)“…Mucopolysaccharidoses (MPSs) are rare inherited lysosomal storage diseases (LSDs) caused by deficient activity in one of the enzymes responsible for…”
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CD1-Restricted T Cells at the Crossroad of Innate and Adaptive Immunity
Published in Journal of immunology research (01-01-2016)“…Lipid-specific T cells comprise a group of T cells that recognize lipids bound to the MHC class I-like CD1 molecules. There are four isoforms of CD1 that are…”
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From Lysosomal Storage Diseases to NKT Cell Activation and Back
Published in International journal of molecular sciences (25-02-2017)“…Lysosomal storage diseases (LSDs) are inherited metabolic disorders characterized by the accumulation of different types of substrates in the lysosome. With a…”
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Invariant natural killer T cells are phenotypically and functionally altered in Fabry disease
Published in Molecular genetics and metabolism (01-04-2013)“…Fabry disease is a lysosomal storage disease belonging to the group of sphingolipidoses. In Fabry disease there is accumulation of mainly globotriaosylceramide…”
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Lipid Antigen Presentation by CD1b and CD1d in Lysosomal Storage Disease Patients
Published in Frontiers in immunology (2019)“…The lysosome has a key role in the presentation of lipid antigens by CD1 molecules. While defects in lipid antigen presentation and in invariant Natural Killer…”
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Transferrin is required for early T‐cell differentiation
Published in Immunology (01-08-2004)“…Summary Transferrin, the major plasma iron carrier, mediates iron entry into cells through interaction with its receptor. Several in vitro studies have…”
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The Biology of Lysosomes: From Order to Disorder
Published in Biomedicines (14-01-2023)“…Since its discovery in 1955, the understanding of the lysosome has continuously increased. Once considered a mere waste removal system, the lysosome is now…”
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Human iNKT Cells Modulate Macrophage Survival and Phenotype
Published in Biomedicines (17-07-2022)“…CD1d-restricted invariant Natural Killer T (iNKT) cells are unconventional innate-like T cells whose functions highly depend on the interactions they establish…”
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Low serum transferrin levels in HFE C282Y homozygous subjects are associated with low CD8 + T lymphocyte numbers
Published in Blood cells, molecules, & diseases (01-11-2005)“…Hereditary hemochromatosis (HH) is a genetic iron overload disease, in the majority of cases associated with homozygosity for the C282Y mutation of the HFE…”
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Inhibition of p38MAP kinase potentiates the JNK/SAPK pathway and AP-1 activity in monocytic but not in macrophage or granulocytic differentiation of HL60 cells
Published in Journal of cellular biochemistry (01-07-2001)“…Monocytic differentiation of HL60 cells induced by 1,25‐dihydroxyvitamin D3 (1,25 D3) has been recently shown (Exp Cell Res 258, 425, 2000) to be enhanced by…”
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Human T cell responses to endogenously presented HLA-A0201 restricted peptides of simian virus 40 large T antigen
Published in Journal of cellular biochemistry (01-07-2001)“…Presence of the simian virus 40 (SV40) has recently been demonstrated in a relatively high percentage of human mesotheliomas and it is associated with the…”
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Identification of Peptides for Immunotherapy of Cancer. It is Still Worth the Effort
Published in Critical reviews in immunology (1998)“…As the nature of the T cell immune response is defined by T cell receptor recognition of small protein fragments, referred to as peptides, the identification…”
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