Search Results - "Macdonald, S"
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Emerging therapeutic opportunities for integrin inhibitors
Published in Nature reviews. Drug discovery (01-01-2022)“…Integrins are cell adhesion and signalling proteins crucial to a wide range of biological functions. Effective marketed treatments have successfully targeted…”
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Schistosome Egg Migration: Mechanisms, Pathogenesis and Host Immune Responses
Published in Frontiers in immunology (20-12-2018)“…Many parasitic worms possess complex and intriguing life cycles, and schistosomes are no exception. To exit the human body and progress to their successive…”
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A systematic review of interventions to promote human papillomavirus (HPV) vaccination in Africa
Published in Public health (London) (01-09-2024)“…We conducted a systematic review to assess the scope and effectiveness of interventions to improve human papilloma virus (HPV) vaccination in Africa from 2006…”
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Search for the Neutron Decay n→X+γ, Where X is a Dark Matter Particle
Published in Physical review letters (13-07-2018)“…Fornal and Grinstein recently proposed that the discrepancy between two different methods of neutron lifetime measurements, the beam and bottle methods, can be…”
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Edge Influence on Forest Structure and Composition in Fragmented Landscapes
Published in Conservation biology (01-06-2005)“…Although forest edges have been studied extensively as an important consequence of fragmentation, a unifying theory of edge influence has yet to be developed…”
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Risk factors for delayed presentation and referral of symptomatic cancer: evidence for common cancers
Published in British journal of cancer (03-12-2009)“…Background: It has been suggested that the known poorer survival from cancer in the United Kingdom, compared with other European countries, can be attributed…”
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The major secreted protein of the whipworm parasite tethers to matrix and inhibits interleukin-13 function
Published in Nature communications (28-05-2019)“…Infection by soil transmitted parasitic helminths, such as Trichuris spp , are ubiquitous in humans and animals but the mechanisms determining persistence of…”
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Sex, receptors, and attachment: a review of individual factors influencing response to oxytocin
Published in Frontiers in neuroscience (01-01-2013)“…As discussed in the larger review in this special issue (MacDonald and Feifel), intranasal oxytocin (OT) is demonstrating a growing potential as a therapeutic…”
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MYC protein interactors in gene transcription and cancer
Published in Nature reviews. Cancer (01-09-2021)“…The transcription factor and oncoprotein MYC is a potent driver of many human cancers and can regulate numerous biological activities that contribute to…”
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The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation
Published in Nature communications (24-02-2021)“…The host defence peptide cathelicidin (LL-37 in humans, mCRAMP in mice) is released from neutrophils by de-granulation, NETosis and necrotic death; it has…”
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Association of lifelong exposure to cognitive reserve-enhancing factors with dementia risk: A community-based cohort study
Published in PLoS medicine (14-03-2017)“…Variation in the clinical manifestation of dementia has been associated with differences in cognitive reserve, although less is known about the cumulative…”
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The role of zinc in growth and cell proliferation
Published in The Journal of nutrition (01-05-2000)“…The inhibition of growth is a cardinal symptom of zinc deficiency. In animals fed a zinc-inadequate diet, both food intake and growth are reduced within 4-5 d…”
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A worldwide, phase III, randomized, controlled, safety and efficacy study of a sirolimus/cyclosporine regimen for prevention of acute rejection in recipients of primary mismatched renal allografts
Published in Transplantation (27-01-2001)“…Despite the various immunosuppressive regimens presently in use, acute rejection in the early postoperative period continues to occur in 20 to 40% of renal…”
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Rate of permafrost thaw and associated plant community dynamics in peatlands of northwestern Canada
Published in The Journal of ecology (01-07-2024)“…Abstract The most rapid climate warming is occurring in northern, permafrost environments. Peatlands of these regions are particularly sensitive to climate…”
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Heparin resistance in COVID-19 patients in the intensive care unit
Published in Journal of thrombosis and thrombolysis (01-08-2020)“…Patients with COVID-19 have a coagulopathy and high thrombotic risk. In a cohort of 69 intensive care unit (ICU) patients we investigated for evidence of…”
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‘Loneliness in the city’: examining socio-economics, loneliness and poor health in the North East of England
Published in Public health (London) (01-12-2018)“…The aim of this study was to discover whether lower socio-economic status is associated with increased experiences of loneliness and isolation. The research…”
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Visual perceptual load induces inattentional deafness
Published in Attention, perception & psychophysics (01-08-2011)“…In this article, we establish a new phenomenon of “inattentional deafness” and highlight the level of load on visual attention as a critical determinant of…”
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Updated Analysis of SWOG-Directed Intergroup Study 0116: A Phase III Trial of Adjuvant Radiochemotherapy Versus Observation After Curative Gastric Cancer Resection
Published in Journal of clinical oncology (01-07-2012)“…Surgical resection of gastric cancer has produced suboptimal survival despite multiple randomized trials that used postoperative chemotherapy or more…”
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Controlled Diffusion of Photoswitchable Receptors by Binding Anti-electrostatic Hydrogen-Bonded Phosphate Oligomers
Published in Journal of the American Chemical Society (25-11-2020)“…Dihydrogen phosphate anions are found to spontaneously associate into anti-electrostatic oligomers via hydrogen bonding interactions at millimolar…”
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