Search Results - "Macdonald, Donald H."

Impact of route and adequacy of nutritional intake on outcomes of allogeneic haematopoietic cell transplantation for haematologic malignancies by Beckerson, Julie, Szydlo, Richard M., Hickson, Mary, Mactier, Catriona E., Innes, Andrew J., Gabriel, Ian H., Palanicawandar, Renuka, Kanfer, Edward J., Macdonald, Donald H., Milojkovic, Dragana, Rahemtulla, Amin, Chaidos, Aristeidis, Karadimitris, Anastasios, Olavarria, Eduardo, Apperley, Jane F., Pavlu, Jiri

“…Allogeneic haematopoietic cell transplantation (HCT) is often associated with poor oral intake due to painful mucositis and gastrointestinal sequalae that…”
Get full text

Optimizing patient selection for myeloablative allogeneic hematopoietic cell transplantation in chronic myeloid leukemia in chronic phase by Pavlů, Jiří, Kew, Andrea K., Taylor-Roberts, Beatrice, Auner, Holger W., Marin, David, Olavarria, Eduardo, Kanfer, Edward J., MacDonald, Donald H., Milojkovic, Dragana, Rahemtulla, Amin, Rezvani, Katayoun, Goldman, John M., Apperley, Jane F., Szydlo, Richard M.

“…Outstanding results have been obtained in the treatment of chronic myeloid leukemia (CML) with first-line imatinib therapy. However, approximately 35% of…”
Get full text

Management of paraproteinaemia by Cook, Lucy, Macdonald, Donald H C

“…A paraprotein is a monoclonal immunoglobulin or light chain present in the blood or urine; it is produced by a clonal population of mature B cells, most…”
Get full text

Posterior reversible encephalopathy after intrathecal methotrexate therapy in diffuse large B‐cell lymphoma by Patel, Amit, Ayto, Robert, MacDonald, Donald H.

Get full text

C‐reactive protein prior to myeloablative allogeneic haematopoietic cell transplantation identifies patients at risk of early‐ and long‐term mortality by Patel, Amit, Szydlo, Richard M., Auner, Holger W., Kanfer, Edward J., MacDonald, Donald H., Milojkovic, Dragana, Altaf, Syed, Innes, Andrew, Gabriel, Ian, Rahemtulla, Amin, Chaidos, Aristeidis, Karadimitris, Anastasios, Olavarria, Eduardo, Apperley, Jane F., Pavlů, Jiří

Get full text

Salvage autologous stem cell transplantation for multiple myeloma relapsing or progressing after up-front autologous transplantation by Auner, Holger W., Szydlo, Richard, Rone, Alero, Chaidos, Aristeidis, Giles, Chrissy, Kanfer, Ed, Macdonald, Donald H., Marin, David, Milojkovic, Dragana, Pavlu, Jiri, Apperley, Jane F., Rahemtulla, Amin

“…Abstract Progression or relapse occurs in the vast majority of patients with multiple myeloma (MM) who undergo up-front autologous hematopoietic cell…”
Get full text

The two faces of myeloproliferative neoplasms: Molecular events underlying lymphoid transformation by Holroyd, Ailsa, Cross, Nicholas C.P, Macdonald, Donald H

“…Abstract Multipotent haematopoietic stem cells pass through stages of differentiation with the progressive loss of developmental options leading to the…”
Get full text

The Hammersmith Hospital hematopathology case of the month: paraspinal B lymphoblastic lymphoma - problems in diagnosis and initial indolent behavior by MacDonald, Donald H., Clark, Ian, Naresh, Kikkeri N.

“…We describe a young man who presented with neurological signs and symptoms, and with a paraspinal soft tissue mass involving the vertebral body at T4. The…”
Get full text

Cellular (FLICE) like inhibitory protein (cFLIP) expression in diffuse large B-cell lymphoma identifies a poor prognostic subset, but fails to predict the molecular subtype by Harris, Jemima, Ibrahim, Hazem, Amen, Furrat, Karadimitris, Anastasios, Naresh, Kikkeri N, Macdonald, Donald H

“…Immunohistochemistry can sub‐classify diffuse large B‐cell lymphoma (DLBCL) into germinal centre B‐cell like (GCB) and non‐GCB subtypes. The latter consists…”
Get full text

Gemcitabine and vinorelbine chemotherapy for refractory or relapsing aggressive non-Hodgkin lymphoma by Sivam, Vanessa, Cook, Lucy, Hughes, George, Karadimitris, Anasatasios, Marks, Alexandra J., Matthey, Francis, Naresh, Kikkeri N., Szydlo, Richard M., Yarranton, Helen, Kanfer, Edward J., Macdonald, Donald H.

Get full text

LACE-conditioned autologous stem cell transplantation for relapsed or refractory diffuse large B-cell lymphoma: treatment outcome and risk factor analysis from a single centre by Pavlů, Jiří, Auner, Holger W., Ellis, Sarah, Szydlo, Richard M., Giles, Chrissy, Contento, Alejandro, Rahemtulla, Amin, Apperley, Jane F., Naresh, Kikkeri, MacDonald, Donald H., Kanfer, Edward J.

“…High‐dose chemotherapy followed by autologous stem cell transplantation (ASCT) is a recognized treatment option for patients with relapsed diffuse large B‐cell…”
Get full text

A novel inherited mutation of the transcription factor RUNX1 causes thrombocytopenia and may predispose to acute myeloid leukaemia by Walker, Logan C., Stevens, Jane, Campbell, Hamish, Corbett, Rob, Spearing, Ruth, Heaton, David, Macdonald, Donald H., Morris, Christine M., Ganly, Peter

“…The RUNX1 (AML1, CBFA2) gene is a member of the runt transcription factor family, responsible for DNA binding and heterodimerization of other non‐DNA binding…”
Get full text

A case of myelofibrosis with a t(4;13)(q25;q12): evidence for involvement of a second 13q12 locus in chronic myeloproliferative disorders by Macdonald, Donald H. C., Lahiri, Diya, Chase, Andrew, Sohal, Jastinder, Goldman, John M., Cross, Nicholas C. P.

“…Aberrations of 13q are frequently found in myeloproliferative disorders (MPD). In a case of primary proliferative polycythaemia which transformed to…”
Get full text

Elevated Preconditioning Serum Levels of C-Reactive Protein Are Associated with Increased Nonrelapse Mortality and Inferior Survival After Reduced Intensity Allogeneic Hematopoietic Stem Cell Transplantation by Pavlu, Jiri, Rezvani, Katayoun, Kishore, Bhuvan, Dieu, Rifca Le, Chakrabartty, Joydeep, Chaidos, Aristeidis, Kanfer, Edward J, Karadimitris, Anastasios, MacDonald, Donald H, Marin, David, Milojkovic, Dragana, O'Boyle, Farah, Rahemtulla, Amin, Slade, David, Goldman, John M, Apperley, Jane F, Szydlo, Richard M

“…Abstract 1945 Identification of prognostic indicators which predict outcome of allogeneic stem cell transplantation (allo-SCT) is important for selection of…”
Get full text

Cryopreserved Allogeneic Peripheral Blood Stem Cells Result in Outcome Equivalent to Those of Fresh Infusions Enabling Rational Scheduling of Donations by Kishore, Bhuvan, Davis, John, Rezvani, Katayoun, Marin, David, Szydlo, Richard M, Sandra, Loaiza, Chrissy, Giles, Chaidos, Aristeidis, Kanfer, Edward J, Karadimitris, Anastasios, MacDonald, Donald H, Milojkovic, Dragana, Rahemtulla, Amin, Goldman, John M, Apperley, Jane F, Pavlu, Jiri

“…Abstract 4052 Donor stem cells are traditionally infused fresh into recipients in the setting of allogeneic hematopoietic stem cell transplantation (allo-SCT)…”
Get full text

Bone marrow involvement in mantle cell lymphoma by Naresh, Kikkeri, Hartley, Sarah, Macdonald, Donald

“…The images depict the characteristic pattern of bone marrow involvement, cytological features and immunophenotype of mantle cell lymphoma…”
Get full text

Specific patterns of chromosomal gains and losses associate with t(3;14), t(8;14), and t(14;18) in diffuse large B-cell lymphoma by Sheth, Avni, de Melo, Valeria A.S, Szydlo, Richard, Macdonald, Donald H, Reid, Alistair G, Wagner, Simon D

“…Abstract Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease. Certain chromosomal translocations are associated with clinical outcome, but it is…”
Get full text

Response to Tyrosine Kinase Inhibitor Therapy In Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation for Advanced Phase Chronic Myeloid Leukemia by Holroyd, Ailsa, Phillips, Elizabeth, Szydlo, Richard, Marin, David, Foroni, Letizia, Khorashad, Jamshid, Milojkovic, Dragana, Kanfer, Edward J., Dazzi, Francesco, MacDonald, Donald H., Rahemtulla, Amin, McLornan, Donal, Gabriel, Ian H, Pavlu, Jiri, Sargent, Jeremy, Goldman, John M., Apperley, Jane F., Rezvani, Katayoun

“…Abstract 3515 With the advent of tyrosine kinase inhibitors (TKI), allogeneic stem cell transplantation (allo-SCT) is largely reserved for patients with CML…”
Get full text

High Frequency and Cell Dose of Invariant NKT Cells In the Graft Are Associated with Lack of Clinically Significant Acute Gvhd In T Cell-Replete Sibling Allografts by Chaidos, Aristeidis, Szydlo, Richard M., Kanfer, Edward J., Dazzi, Francesco, MacDonald, Donald H., Marin, David, Milojkovic, Dragana, Pavlu, Jiri, Davis, John, Rezvani, Katayoun, Rahemtulla, Amin, Roberts, Irene, Apperley, Jane F., Karadimitris, Anastasios

“…Abstract 2539 Invariant NKT (iNKT) cells are a potent, CD1d-restricted immunomodulatory subset of T cells that regulate a variety of experimental immune…”
Get full text

Preconditioning Level of C-Reactive Protein and Disease Stage Are Key Prognostic Factors In Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation by Pavlu, Jiri, Shah, Rajvi, Auner, Holger W., Milojkovic, Dragana, Marin, David, Sargent, Jeremy, Rahemtulla, Amin, MacDonald, Donald H., Kanfer, Edward J., Rezvani, Katayoun, Dazzi, Francesco, Goldman, John M., Apperley, Jane F., Szydlo, Richard M.

“…Abstract 3488 It is important to determine prognostic indicators which may predict outcome of hematopoietic stem cell transplantation (HCT). The European Group…”
Get full text