Search Results - "Maccoll, G S"

The hypothalamic-pituitary-gonadal axis: immune function and autoimmunity by Tanriverdi, F, Silveira, LF, MacColl, GS, Bouloux, PM

“…GnRH and sex steroids play an important role in immune system modulation and development. GnRH and the GnRH receptor are produced locally by immune cells,…”
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Novel homozygous splice acceptor site GnRH receptor (GnRHR) mutation: Human GnRHR knockout by SILVEIRA, L. F. G, STEWART, P. M, THOMAS, M, CLARK, D. A, BOULOUX, P. M. G, MACCOLL, G. S

“…Mutations in the GnRH receptor (GnRHR) have been shown to be responsible for a significant number of autosomic recessive and, less commonly, sporadic cases of…”
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Expression of gonadotropin-releasing hormone type-I (GnRH-I) and type-II (GnRH-II) in human peripheral blood mononuclear cells (PMBCs) and regulation of B-lymphoblastoid cell proliferation by GnRH-I and GnRH-II by Tanriverdi, F, Gonzalez-Martinez, D, Silveira, L F G, Hu, Y, Maccoll, G S, Travers, P, Bouloux, P M G

“…GnRH-I and its receptor (GnRHR-I) have previously been demonstrated and shown to be biologically active in the immune system, notably within T cells. Recently…”
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Using skeletal muscle as an artificial endocrine tissue by MacColl, GS, Goldspink, G, Bouloux, PM

“…Gene transfer into muscle tissue is currently being developed as a method for the production, secretion and delivery of therapeutic proteins. This methodology…”
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Molecular modelling and experimental studies of mutation and cell-adhesion sites in the fibronectin type III and whey acidic protein domains of human anosmin-1 by Robertson, A, MacColl, G S, Nash, J A, Boehm, M K, Perkins, S J, Bouloux, P M

“…Anosmin-1, the gene product of the KAL gene, is implicated in the pathogenesis of X-linked Kallmann's syndrome. Anosmin-1 protein expression is restricted to…”
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Optimisation of growth hormone production by muscle cells using plasmid DNA by MacColl, GS, Novo, FJ, Marshall, NJ, Waters, M, Goldspink, G, Bouloux, PM

“…The production of peptide hormones by skeletal muscle tissue is a promising area of gene therapy. Skeletal muscle myogenesis can be induced in vitro, resulting…”
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Idiopathic gonadotrophin deficiency: genetic questions addressed through phenotypic characterization by Quinton, Richard, Duke, Véronique M., Robertson, Alexis, Kirk, Jeremy M. W., Matfin, Glenn, De Zoysa, Priyal A., Azcona, Christina, MacColl, Gavin S., Jacobs, Howard S., Conway, Gerard S., Besser, Michael, Stanhope, Richard G., Bouloux, Pierre-Marc G.

“…OBJECTIVE The association of idiopathic hypogonadotrophic hypogonadism (IHH) with congenital olfactory deficit defines Kallmann's syndrome (KS). Although a…”
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Biology of KAL1 and its orthologs: implications for X-linked Kallmann syndrome and the search for novel candidate genes by MacColl, Gavin S, Quinton, Richard, Bülow, Hannes E

“…Kallmann syndrome is characterised by congenital hypogonadotropic hypogonadism and anosmia, sometimes with other non-reproductive defects. Although multiple…”
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Ghrelin Can Bind to a Species of High Density Lipoprotein Associated with Paraoxonase by Beaumont, Nicholas J, Skinner, Vernon O, Tan, Tricia M-M, Ramesh, Bala S, Byrne, Dominic J, MacColl, Gavin S, Keen, Jeff N, Bouloux, Pierre M, Mikhailidis, Dimitri P, Bruckdorfer, K Richard, Vanderpump, Mark P, Srai, Kaila S

“…Ghrelin is a 28-residue peptide hormone that is principally released from the stomach during fasting and prior to eating. Two forms are present in human…”
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Novel Homozygous Splice Acceptor Site GnRH Receptor (GnRHR) Mutation: Human GnRHR “Knockout” by Silveira, L. F. G., Stewart, P. M., Thomas, M., Clark, D. A., Bouloux, P. M. G., MacColl, G. S.

“…Mutations in the GnRH receptor (GnRHR) have been shown to be responsible for a significant number of autosomic recessive and, less commonly, sporadic cases of…”
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Hypogonadotropic hypogonadism by Silveira, Leticia F G, MacColl, Gavin S, Bouloux, Pierre M G

“…Hypogonadotropic hypogonadism is characterized by failure of gonadal function secondary to deficient gonadotropin secretion, resulting from either a pituitary…”
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Kallmann’s syndrome: molecular pathogenesis by Hu, Youli, Tanriverdi, Fatih, MacColl, Gavin S., Bouloux, Pierre-Marc G.

“…Kallmann’s syndrome (KS) is a genetic condition characterised by hypogonadotrophic hypogonadism (HH) and anosmia; although these are the defining features of…”
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Growth hormone therapy for non-islet cell tumor hypoglycemia by Silveira, Letícia F G, Bouloux, Pierre M G, MacColl, Gavin S, Camacho-Hubner, Cecilia, Miraki-Moud, Farideh

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