Search Results - "Maccioni, Hugo J F"

Cellular and molecular biology of glycosphingolipid glycosylation by Maccioni, Hugo J. F., Quiroga, Rodrigo, Ferrari, Mariana L.

“…J. Neurochem. (2011) 117, 589–602. Brain tissue is characterized by its high glycosphingolipid content, particularly those containing sialic acid…”
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Defective GM3 Synthesis in Cog2 Null Mutant CHO Cells Associates to Mislocalization of Lactosylceramide Sialyltransferase in the Golgi Complex by Spessott, Waldo, Uliana, Andrea, Maccioni, Hugo J. F.

“…The conserved oligomeric Golgi (COG) complex is a eight subunit (COG1 to 8) tethering complex involved in the retrograde trafficking of multiple Golgi…”
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Spatial Organization and Stoichiometry of N-Terminal Domain-Mediated Glycosyltransferase Complexes in Golgi Membranes Determined by Fret Microscopy by Ferrari, Mariana L., Gomez, Guillermo A., Maccioni, Hugo J. F.

“…The functional link between glycolipid glycosyltransferases (GT) relies on the ability of these proteins to form organized molecular complexes. The…”
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Calsenilin and CALP interact with the cytoplasmic tail of UDP-Gal:GA2/GM2/GD2 beta-1,3-galactosyltransferase by Quintero, Cristián A, Valdez-Taubas, Javier, Ferrari, Mariana L, Haedo, Sergio D, Maccioni, Hugo J F

“…GalT2 (UDP-Gal:GA2/GM2/GD2 beta-1,3-galactosyltransferase) is a Golgi-resident type II membrane protein that participates in the synthesis of…”
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Glycosylation of glycolipids in the Golgi complex by Maccioni, Hugo J.F

“…Gangliosides are a family of glycolipids characterized by containing a variable number of sialic acid residues. Nearly, all animal cells contain at least some…”
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A novel motif at the C-terminus of palmitoyltransferases is essential for Swf1 and Pfa3 function in vivo by González Montoro, Ayelén, Quiroga, Rodrigo, Maccioni, Hugo J F, Valdez Taubas, Javier

“…S-acylation (commonly known as palmitoylation) is a widespread post-translational modification that consists of the addition of a lipid molecule to cysteine…”
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c-Fos Activates Glucosylceramide Synthase and Glycolipid Synthesis in PC12 Cells by Crespo, Pilar M., Silvestre, David C., Gil, Germán A., Maccioni, Hugo J.F., Daniotti, José L., Caputto, Beatriz L.

“…It has been demonstrated that c-Fos has, in addition to its well recognized AP-1 transcription factor activity, the capacity to associate to the endoplasmic…”
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Physical and Functional Association of Glycolipid N-Acetyl-Galactosaminyl and Galactosyl Transferases in the Golgi Apparatus by Giraudo, Claudio G., Daniotti, Jose L., Hugo J. F. Maccioni

“…Glycolipid glycosyltransferases catalyze the stepwise transfer of monosaccharides from sugar nucleotides to proper glycolipid acceptors. They are Golgi…”
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Modulation of GalT1 and SialT1 Sub-Golgi Localization by SialT2 Expression Reveals an Organellar Level of Glycolipid Synthesis Control by Uliana, Andrea S., Crespo, Pilar M., Martina, Jose A., Daniotti, Jose L., Maccioni, Hugo J.F.

“…Ganglioside glycosyltransferases organize as multienzyme complexes that localize in different sub-Golgi compartments. Here we studied whether in CHO-K1 cells…”
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Organization of the synthesis of glycolipid oligosaccharides in the Golgi complex by Maccioni, Hugo J.F., Quiroga, Rodrigo, Spessott, Waldo

“…Glycolipids constitute a complex family of amphipathic molecules structurally characterized by a hydrophilic mono- or oligo-saccharide moiety linked to a…”
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Short transmembrane domains with high-volume exoplasmic halves determine retention of Type II membrane proteins in the Golgi complex by Quiroga, Rodrigo, Trenchi, Alejandra, González Montoro, Ayelén, Valdez Taubas, Javier, Maccioni, Hugo J F

“…It is still unclear why some proteins that travel along the secretory pathway are retained in the Golgi complex whereas others make their way to the plasma…”
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Glycosyltransferase complexes improve glycolipid synthesis by Spessott, Waldo, Crespo, Pilar M., Daniotti, José Luis, Maccioni, Hugo J.F.

“…► GM3 synthase (GM3S) activity of CHO-K1 cells increases when transfected with GD3 synthase (GD3S). ► The products of the GM3S assay were GM3 in CHO-K1 cells…”
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Identification of a Site in Sar1 Involved in the Interaction with the Cytoplasmic Tail of Glycolipid Glycosyltransferases by Quintero, Cristián A., Giraudo, Claudio G., Villarreal, Marcos, Montich, Guillermo, Maccioni, Hugo J.F.

“…Glycolipid glycosyltransferases (GGT) are transported from the endoplasmic reticulum (ER) to the Golgi, their site of residence, via COPII vesicles. An…”
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Ganglioside Glycosyltransferases Organize in Distinct Multienzyme Complexes in CHO-K1 Cells by Giraudo, Claudio G., Maccioni, Hugo J.F.

“…The synthesis of gangliosides is compartmentalized in the Golgi complex. In most cells, glycosylation of LacCer, GM3, and GD3 to form higher order species…”
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Short length transmembrane domains having voluminous exoplasmic halves determine retention of Type II membrane proteins in the Golgi complex by Quiroga, Rodrigo, Trenchi, Alejandra, Montoro, Ayelén González, Taubas, Javier Valdez, Maccioni, Hugo J. F.

“…It is still unclear why some proteins that travel along the secretory pathway are retained in the Golgi complex while others follow their way to the plasma…”
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Cog2 Null Mutant CHO Cells Show Defective Sphingomyelin Synthesis by Spessott, Waldo, Uliana, Andrea, Maccioni, Hugo J.F.

“…The COG (conserved oligomeric Golgi complex) is a Golgi-associated tethering complex involved in retrograde trafficking of multiple Golgi enzymes. COG…”
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Content of endoplasmic reticulum and Golgi complex membranes positively correlates with the proliferative status of brain cells by Silvestre, David C., Maccioni, Hugo J.F., Caputto, Beatriz L.

“…Although the molecular and cellular basis of particular events that lead to the biogenesis of membranes in eukaryotic cells has been described in detail,…”
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Cytoplasmic Tails of SialT2 and GalNAcT Impose Their Respective Proximal and Distal Golgi Localization by Uliana, Andrea S., Giraudo, Claudio G., Maccioni, Hugo J. F.

“…Complex glycolipid synthesis is catalyzed by different glycosyltransferases resident of the Golgi complex. Most of them are type II membrane proteins…”
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Understanding the stepwise synthesis of glycolipids by MACCIONI, Hugo J. F, GIRAUDO, Claudio G, DANIOTTI, José Luis

“…Glycolipid expression is highly regulated during development and differeniation. The control relies mainly on transcriptional modulation of key…”
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Ganglioside glycosyltransferases and newly synthesized gangliosides are excluded from detergent-insoluble complexes of Golgi membranes by Crespo, Pilar M, Zurita, Adolfo R, Giraudo, Claudio G, Maccioni, Hugo J F, Daniotti, Jose L

“…GEM (glycosphingolipid-enriched microdomains) are specialized detergent-resistant domains of the plasma membrane in which some gangliosides concentrate…”
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