Search Results - "Maccaroni, Elena"

Mismatch repair deficiency may affect clinical outcome through immune response activation in metastatic gastric cancer patients receiving first-line chemotherapy by Giampieri, Riccardo, Maccaroni, Elena, Mandolesi, Alessandra, Del Prete, Michela, Andrikou, Kalliopi, Faloppi, Luca, Bittoni, Alessandro, Bianconi, Maristella, Scarpelli, Marina, Bracci, Raffaella, Scartozzi, Mario, Cascinu, Stefano

“…Introduction The microsatellite-instable gastric cancer subtype, because of its supposed high antigenic potential, is a promising candidate for immunotherapy…”
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Transient Sunitinib Resistance in Gastrointestinal Stromal Tumors by Bracci, Raffaella, Maccaroni, Elena, Cascinu, Stefano

“…Two patients are described in whom response to sunitinib as second-line therapy was followed by disease progression. After they received other treatments that…”
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Locally advanced rectal cancer:The importance of a multidisciplinary approach by Berardi, Rossana, Maccaroni, Elena, Onofri, Azzurra, Morgese, Francesca, Torniai, Mariangela, Tiberi, Michela, Ferrini, Consuelo, Cascinu, Stefano

“…Rectal cancer accounts for a relevant part of colorectal cancer cases,with a mortality of 4-10/100000 per year.The development of locoregional recurrences and…”
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The role of LDH serum levels in predicting global outcome in HCC patients undergoing TACE: implications for clinical management by Scartozzi, Mario, Faloppi, Luca, Bianconi, Maristella, Giampieri, Riccardo, Maccaroni, Elena, Bittoni, Alessandro, Del Prete, Michela, Loretelli, Cristian, Belvederesi, Laura, Svegliati Baroni, Gianluca, Cascinu, Stefano

“…In many tumor types serum lactate dehydrogenase (LDH) levels is an indirect marker of tumor hypoxia, neo-angiogenesis and worse prognosis. However data about…”
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Androgen receptor expression in early triple-negative breast cancer: clinical significance and prognostic associations by Pistelli, Mirco, Caramanti, Miriam, Biscotti, Tommasina, Santinelli, Alfredo, Pagliacci, Alessandra, De Lisa, Mariagrazia, Ballatore, Zelmira, Ridolfi, Francesca, Maccaroni, Elena, Bracci, Raffaella, Berardi, Rossana, Battelli, Nicola, Cascinu, Stefano

“…Triple-negative breast cancers (TNBC) are characterized by aggressive tumour biology resulting in a poor prognosis. Androgen receptor (AR) is one of newly…”
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Evolving strategies for the treatment of hepatocellular carcinoma: From clinical-guided to molecularly-taylored therapeutic options by Faloppi, Luca, Scartozzi, Mario, Maccaroni, Elena, Di Pietro Paolo, Marzia, Berardi, Rossana, Del Prete, Michela, Cascinu, Stefano

“…Abstract Hepatocellular carcinoma (hepatocellular carcinoma, HCC) is the commonest primary liver cancer (80–90%) and represents the leading cause of…”
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Expectations and psychological issues before genetic counseling: analysis of distress determinant factors by Ballatore, Zelmira, Bracci, Raffaella, Maccaroni, Elena, Svarca, Lucia, Bianchi, Francesca, Belvederesi, Laura, Bruciati, Cristiana, Pagliaretta, Silvia, Murrone, Alberto, Bini, Federica, Pistelli, Mirco, Ricci, Giulia, Berardi, Rossana

“…Hereditary non-polyposis colorectal cancer (HNPCC) and Hereditary Breast and Ovarian Cancer Syndrome (HBOC) are the most common hereditary cancer syndromes in…”
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Correction to: Expectations and psychological issues before genetic counseling: analysis of distress determinant factors by Ballatore, Zelmira, Bracci, Raffaella, Maccaroni, Elena, Svarca, Lucia, Bianchi, Francesca, Belvederesi, Laura, Brugiati, Cristiana, Pagliaretta, Silvia, Murrone, Alberto, Bini, Federica, Pistelli, Mirco, Ricci, Giulia, Berardi, Rossana

“…[This corrects the article DOI: 10.1186/s13053-020-00142-1.]…”
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Lynch syndrome-associated lung cancer: pitfalls of an immunotherapy-based treatment strategy in an unusual tumor type by Maccaroni, Elena, Lenci, Edoardo, Agostinelli, Veronica, Cognigni, Valeria, Giampieri, Riccardo, Mazzanti, Paola, Di Pietro Paolo, Marzia, Bianchi, Francesca, Brugiati, Cristiana, Belvederesi, Laura, Pagliaretta, Silvia, Mandolesi, Alessandra, Scarpelli, Marina, Murrone, Alberto, Morgese, Francesca, Ballatore, Zelmira, Berardi, Rossana

“…Lynch syndrome is a hereditary cancer predisposition syndrome caused by germline alterations in mismatch repair (MMR) genes leading to increased risk of colon…”
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Phosphorylated AKT and MAPK expression in primary tumours and in corresponding metastases and clinical outcome in colorectal cancer patients receiving irinotecan-cetuximab by Scartozzi, Mario, Giampieri, Riccardo, Maccaroni, Elena, Mandolesi, Alessandra, Biagetti, Simona, Alfonsi, Simona, Giustini, Lucio, Loretelli, Cristian, Faloppi, Luca, Bittoni, Alessandro, Bianconi, Maristella, Del Prete, Michela, Bearzi, Italo, Cascinu, Stefano

“…Clinical observations suggested that a non negligible proportion of patients, ranging from 40% to 70%, does not seem to benefit from the use of anti-EGFR…”
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Acute Peripheral Motor Neuropathy Induced by Oxaliplatin-Correlated Hypokalaemia by Giampieri, Riccardo, Maccaroni, Elena, Sotte, Valeria, Baleani, Maria G., Meletani, Tania, Giglio, Enrica, Pecci, Federica, Bittoni, Alessandro, Lanese, Andrea, Cantini, Luca, Mentrasti, Giulia, Lucarelli, Alessandra, Berardi, Rossana

“…Neurotoxicity is one of the most common side effects of oxaliplatin-based therapy. Most patients who receive at least 3–4 months of treatment suffer from…”
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New Insights into Hormonal Therapies in Uterine Sarcomas by Maccaroni, Elena, Lunerti, Valentina, Agostinelli, Veronica, Giampieri, Riccardo, Zepponi, Laura, Pagliacci, Alessandra, Berardi, Rossana

“…Uterine sarcoma (US) is a rare mesenchymal malignant cancer type, accounting for 3-7% of uterine malignancies. US prognosis is still poor due to high local and…”
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Pre-treatment neutrophil to lymphocyte ratio may be a useful tool in predicting survival in early triple negative breast cancer patients by Pistelli, Mirco, De Lisa, Mariagrazia, Ballatore, Zelmira, Caramanti, Miriam, Pagliacci, Alessandra, Battelli, Nicola, Ridolfi, Francesca, Santoni, Matteo, Maccaroni, Elena, Bracci, Raffaella, Santinelli, Alfredo, Biscotti, Tommasina, Berardi, Rossana, Cascinu, Stefano

“…There is a growing body of evidence that immune response plays a large role in cancer outcome. The neutrophil to lymphocyte ratio (NLR) has been used as a…”
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Endometriosis-associated Clear Cell Carcinoma of the Abdominal Wall After Caesarean Section: A Case Report and Review of the Literature by GIANNELLA, LUCA, SERRI, MATTEO, MACCARONI, ELENA, DI GIUSEPPE, JACOPO, CARPINI, GIOVANNI DELLI, BERARDI, ROSSANA, SOPRACORDEVOLE, FRANCESCO, CIAVATTINI, ANDREA

“…BACKGROUND/AIMClear cell carcinoma of the abdominal wall is a sporadic event. To date, about thirty cases have been reported in the literature. This article…”
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BRCA mutations and gastrointestinal cancers: When to expect the unexpected? by Maccaroni, Elena, Giampieri, Riccardo, Lenci, Edoardo, Scortichini, Laura, Bianchi, Francesca, Belvederesi, Laura, Brugiati, Cristiana, Pagliaretta, Silvia, Ambrosini, Elisa, Berardi, Rossana

“…BRCA1/2 pathogenic variants are widely known as major risk factors mainly for breast and ovarian cancer, while their role in gastrointestinal (GI) malignancies…”
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Off-target effects and clinical outcome in metastatic colorectal cancer patients receiving regorafenib: The TRIBUTE analysis by Giampieri, Riccardo, Prete, Michela del, Prochilo, Tiziana, Puzzoni, Marco, Pusceddu, Valeria, Pani, Fabiana, Maccaroni, Elena, Mascia, Roberta, Baleani, Maria Giuditta, Meletani, Tania, Berardi, Rossana, Lanzillo, Anna Maria, Mariotti, Stefano, Zaniboni, Alberto, Cascinu, Stefano, Scartozzi, Mario

“…Regorafenib is an orally administered multikinase inhibitor indicated for the treatment of heavily pretreated metastatic colorectal cancer patients with good…”
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Developments in the management of advanced soft-tissue sarcoma - olaratumab in context by Moroncini, Gianluca, Maccaroni, Elena, Fiordoliva, Ilaria, Pellei, Chiara, Gabrielli, Armando, Berardi, Rossana

“…Lartruvo (olaratumab) is a fully human immunoglobulin G subclass 1 (IgG1) monoclonal antibody that inhibits platelet-derived growth factor receptor alpha…”
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Body Mass Index and Hormone Receptor Status Influence Recurrence Risk in HER2-Positive Early Breast Cancer Patients by Cantini, Luca, Pistelli, Mirco, Merloni, Filippo, Fontana, Andrea, Bertolini, Ilaria, De Angelis, Claudia, Bastianelli, Lucia, Della Mora, Arianna, Santinelli, Alfredo, Savini, Agnese, Maccaroni, Elena, Diodati, Lucrezia, Falcone, Alfredo, Berardi, Rossana

“…A reliable risk stratification on the basis of tumor biology and host factors of HER2-positive (HER2+) early breast cancer (eBC) patients is needed. The aim of…”
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Molecular biomarkers of resistance to anti-EGFR treatment in metastatic colorectal cancer, from classical to innovation by Giampieri, Riccardo, Scartozzi, Mario, Del Prete, Michela, Maccaroni, Elena, Bittoni, Alessandro, Faloppi, Luca, Bianconi, Maristella, Cecchini, Luca, Cascinu, Stefano

“…Abstract Background Systematic dissection of the EGFR pathway was considered as the best way to identify putative markers of resistance to anti-EGFR therapies…”
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5-Fluorouracil pharmacogenomics: still rocking after all these years? by Scartozzi, Mario, Maccaroni, Elena, Giampieri, Riccardo, Pistelli, Mirco, Bittoni, Alessandro, Del Prete, Michela, Berardi, Rossana, Cascinu, Stefano

“…The 5-fluorouracil (5-FU) metabolic pathway is mainly dependent on the activity of several intracellular enzymes. Among them, four in particular; thymidylate…”
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