Search Results - "Macarthur, Linda"
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1
Plasma phospholipids identify antecedent memory impairment in older adults
Published in Nature medicine (01-04-2014)“…Howard Federoff and colleagues have identified a ten-metabolite profile in the blood that can determine with 90% certainty whether a cognitively normal elderly…”
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2
Synthesis and evaluation of hermitamides A and B as human voltage-gated sodium channel blockers
Published in Bioorganic & medicinal chemistry (15-07-2011)“…Hermitamides A and B are lipopeptides isolated from a Papau New Guinea collection of the marine cyanobacterium Lyngbya majuscula. We hypothesized that the…”
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3
Differences in cytokine gene expression profile between acute and secondary injury in adult rat spinal cord
Published in Experimental neurology (01-11-2003)“…It is likely that the environment within the injured spinal cord influences the capacity of fetal spinal cord transplants to support axonal growth. We have…”
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4
Synthesis and biological evaluation of a fluorescent analog of phenytoin as a potential inhibitor of neuropathic pain and imaging agent
Published in Bioorganic & medicinal chemistry (01-09-2012)“…Here we report on a novel fluorescent analog of phenytoin as a potential inhibitor of neuropathic pain with potential use as an imaging agent. Compound 2…”
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5
Quantitative analysis of the heteromeric neuronal nicotinic receptors in the rat hippocampus
Published in Journal of neurochemistry (01-11-2010)“…J. Neurochem. (2010) 115, 625-634. The objective of this study was to identify and quantify the heteromeric neuronal nicotinic receptors (nAChRs) in the rat…”
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6
Activity-based therapies to promote forelimb use after a cervical spinal cord injury
Published in Journal of neurotrauma (01-10-2009)“…Significant interest exists in strategies for improving forelimb function following spinal cord injury. We investigated the effect of enriched housing combined…”
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7
Axonal Regeneration and Functional Recovery after Complete Spinal Cord Transection in Rats by Delayed Treatment with Transplants and Neurotrophins
Published in The Journal of neuroscience (01-12-2001)“…Little axonal regeneration occurs after spinal cord injury in adult mammals. Regrowth of mature CNS axons can be induced, however, by altering the intrinsic…”
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8
Delayed rehabilitation with task-specific therapies improves forelimb function after a cervical spinal cord injury
Published in Restorative neurology and neuroscience (2011)“…The effect of activity based therapies on restoring forelimb function in rats was evaluated when initiated one month after a cervical spinal cord injury. Adult…”
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9
Network modeling to identify new mechanisms and therapeutic targets for Parkinson's disease
Published in Expert review of neurotherapeutics (01-06-2013)“…Biomolecules in subnetworks are the focus of a new strategy to develop drugs that halt complex diseases. In this article, the authors use genome-wide…”
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10
Retrograde and anterograde transport of HIV protein gp120 in the nervous system
Published in Brain, behavior, and immunity (01-03-2009)“…Abstract Neurodegeneration and gliosis are prominent pathological features of subjects with human immunodeficiency virus (HIV) dementia complex (HAD). In these…”
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11
Delayed intervention with transplants and neurotrophic factors supports recovery of forelimb function after cervical spinal cord injury in adult rats
Published in Journal of neurotrauma (01-05-2006)“…The adult central nervous system is capable of considerable anatomical reorganization and functional recovery after injury. Functional outcomes, however, vary…”
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12
The role of executive attention in healthy older adults' concurrent walking and counting
Published 01-01-2013“…Completing activities of daily life relies on using both cognitive and physical resources efficiently, but these are affected by age. This may be due either to…”
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Dissertation -
13
AP-1-related proteins bind to the enkephalin CRE-2 element in adrenal chromaffin cells
Published in Journal of neurochemistry (01-12-1996)“…Chromaffin cells of the adrenal medulla are neural crest-derived neuroendocrine cells that express neuropeptide genes in vivo and in vitro. As such these cells…”
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14
The drive to strive: Exploring the experiences of elite-level adolescent artistic performers
Published 01-01-2008“…In order to excel, aspiring classical musicians and artistic gymnasts must be highly motivated and possess certain characteristics, which allow them to spend…”
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Dissertation -
15
X-ray and electron microanalyses of a Martian breccia and comet 81p/wild 2 samples
Published 01-01-2018“…X-ray spectroscopy and electron microscopy have been used to study a martian breccia meteorite and grains from Comet 81P/Wild 2 retrieved by NASA's Stardust…”
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Dissertation -
16
Neuropeptide genes: Targets of activity-dependent signal transduction
Published in Peptides (1996)“…Neuroendocrine cells respond to hormones and synaptic input by increasing or decreasing their own electrical activity and secretory output, and by changes in…”
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Book Review Journal Article -
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The drive to strive: Exploring the experiences of elite-level adolescent artistic performers
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Dissertation -
18
Identification of a TPA-responsive element mediating preferential transactivation of the galanin gene promoter in chromaffin cells
Published in The Journal of biological chemistry (04-03-1994)“…The gene encoding the neuropeptide galanin is upregulated by second messenger signal transduction pathways in bovine chromaffin cells. To identify its…”
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19
Tumor-Suppressor Function of Muscarinic Acetylcholine Receptors is Associated with Activation of Receptor-Operated Calcium Influx
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-1993)“…Several members of the family of guanine nucleotide-binding protein (G protein)-coupled receptors have recently been shown to induce agonist-dependent foci…”
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20
Enkephalin gene transcription in bovine chromaffin cells is regulated by calcium and protein kinase A signal transduction pathways: identification of DNase I-hypersensitive sites
Published in Molecular pharmacology (01-09-1993)“…The bovine enkephalin gene is responsive to multiple signaling pathways in primary chromaffin cell cultures. We examined the effects of activation of the…”
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