Search Results - "MacQueen, Luke"
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Fibre-infused gel scaffolds guide cardiomyocyte alignment in 3D-printed ventricles
Published in Nature materials (01-08-2023)“…Hydrogels are attractive materials for tissue engineering, but efforts to date have shown limited ability to produce the microstructural features necessary to…”
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2
Mesenchymal stem cell mechanobiology and emerging experimental platforms
Published in Journal of the Royal Society interface (06-07-2013)“…Experimental control over progenitor cell lineage specification can be achieved by modulating properties of the cell's microenvironment. These include physical…”
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3
Recreating the heart's helical structure-function relationship with focused rotary jet spinning
Published in Science (American Association for the Advancement of Science) (08-07-2022)“…Helical alignments within the heart's musculature have been speculated to be important in achieving physiological pumping efficiencies. Testing this…”
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4
Engineered In Vitro Disease Models
Published in Annual review of pathology (01-01-2015)“…The ultimate goal of most biomedical research is to gain greater insight into mechanisms of human disease or to develop new and improved therapies or…”
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5
Inhibition of mTOR Signaling Enhances Maturation of Cardiomyocytes Derived From Human-Induced Pluripotent Stem Cells via p53-Induced Quiescence
Published in Circulation (New York, N.Y.) (28-01-2020)“…BACKGROUND:Current differentiation protocols to produce cardiomyocytes from human induced pluripotent stem cells (iPSCs) are capable of generating highly pure…”
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6
Muscle tissue engineering in fibrous gelatin: implications for meat analogs
Published in NPJ science of food (21-10-2019)“…Bioprocessing applications that derive meat products from animal cell cultures require food-safe culture substrates that support volumetric expansion and…”
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7
Development of Biodegradable and Antimicrobial Electrospun Zein Fibers for Food Packaging
Published in ACS sustainable chemistry & engineering (12-10-2020)“…There is an urgent need to develop biodegradable and nontoxic materials from biopolymers and nature-derived antimicrobials to enhance food safety and quality…”
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8
Microdevice arrays with strain sensors for 3D mechanical stimulation and monitoring of engineered tissues
Published in Biomaterials (01-07-2018)“…Native and engineered tissue development are regulated by the integrative effects of multiple microenvironmental stimuli. Microfabricated bioreactor array…”
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9
High-throughput coating with biodegradable antimicrobial pullulan fibres extends shelf life and reduces weight loss in an avocado model
Published in Nature food (01-06-2022)“…Food waste and food safety motivate the need for improved food packaging solutions. However, current films/coatings addressing these issues are often limited…”
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10
A tissue-engineered scale model of the heart ventricle
Published in Nature biomedical engineering (01-12-2018)“…Laboratory studies of the heart use cell and tissue cultures to dissect heart function yet rely on animal models to measure pressure and volume dynamics. Here,…”
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11
Production of Synthetic, Para‐Aramid and Biopolymer Nanofibers by Immersion Rotary Jet‐Spinning
Published in Macromolecular materials and engineering (01-01-2017)“…Nanofiber production platforms commonly rely on volatile carrier solvents or high voltages. Production of nanofibers comprised of charged polymers or polymers…”
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12
Design and Fabrication of Fibrous Nanomaterials Using Pull Spinning
Published in Macromolecular materials and engineering (01-03-2017)“…The assembly of natural and synthetic polymers into fibrous nanomaterials has applications ranging from textiles, tissue engineering, photonics, and catalysis…”
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13
Electromechanical deformation of mammalian cells in suspension depends on their cortical actin thicknesses
Published in Journal of biomechanics (15-11-2012)“…Abstract The mechanical properties of mammalian cells are largely determined by their cytoskeletons (CSKs), which comprise several distinct but interacting…”
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14
Spatiotemporal cell junction assembly in human iPSC-CM models of arrhythmogenic cardiomyopathy
Published in Stem cell reports (12-09-2023)“…Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiac disorder that causes life-threatening arrhythmias and myocardial dysfunction. Pathogenic variants…”
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15
Acute Pergolide Exposure Stiffens Engineered Valve Interstitial Cell Tissues and Reduces Contractility In Vitro
Published in Cardiovascular pathology (01-07-2016)“…Abstract Medications based on ergoline-derived dopamine and serotonin agonists are associated with off-target toxicities that include valvular heart disease…”
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16
Addendum: A tissue-engineered scale model of the heart ventricle
Published in Nature biomedical engineering (01-11-2022)Get full text
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17
Gene delivery by electroporation after dielectrophoretic positioning of cells in a non-uniform electric field
Published in Bioelectrochemistry (Amsterdam, Netherlands) (01-04-2008)“…We report the use of dielectrophoresis (DEP) to position U-937 monocytes within a non-uniform electric field, prior to electroporation (EP) for gene delivery…”
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18
Macromol. Mater. Eng. 3/2017
Published in Macromolecular materials and engineering (01-03-2017)“…Front Cover: Pull spinning is a new nanofiber manufacturing technique that uses a high‐speed rotating bristle to draw anisotropic nanofibers from a polymer…”
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Macromol. Mater. Eng. 1/2017
Published in Macromolecular materials and engineering (01-01-2017)“…Front Cover: Utilizing a precipitant vortex, a novel nanofiber platform produces Kevlar, nylon, DNA, and alginate nanofibers for high‐performance composites…”
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20
PECVD of Nanocrystalline Si Layers on High-Tg Polymer Substrates
Published in Plasma processes and polymers (16-01-2006)“…Hydrogenated nanocrystalline silicon (nc‐Si:H) was deposited by plasma‐enhanced chemical vapor deposition (PECVD) on transparent polymers in order to qualify…”
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