Search Results - "MacLean, Emily"

Diagnostic accuracy of serological tests for covid-19: systematic review and meta-analysis by Lisboa Bastos, Mayara, Tavaziva, Gamuchirai, Abidi, Syed Kunal, Campbell, Jonathon R, Haraoui, Louis-Patrick, Johnston, James C, Lan, Zhiyi, Law, Stephanie, MacLean, Emily, Trajman, Anete, Menzies, Dick, Benedetti, Andrea, Ahmad Khan, Faiz

“…Abstract Objective To determine the diagnostic accuracy of serological tests for coronavirus disease-2019 (covid-19). Design Systematic review and…”
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Biomarkers for diagnosis of childhood tuberculosis: A systematic review by Togun, Toyin Omotayo, MacLean, Emily, Kampmann, Beate, Pai, Madhukar

“…As studies of biomarkers of tuberculosis (TB) disease provide hope for a simple, point-of-care test, we aimed to synthesize evidence on biomarkers for…”
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Advances in Molecular Diagnosis of Tuberculosis by MacLean, Emily, Kohli, Mikashmi, Weber, Stefan F, Suresh, Anita, Schumacher, Samuel G, Denkinger, Claudia M, Pai, Madhukar

“…Molecular tests for tuberculosis (TB) have the potential to help reach the three million people with TB who are undiagnosed or not reported each year and to…”
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Target product profiles: tests for tuberculosis treatment monitoring and optimization by Gupta-Wright, Ankur, den Boon, Saskia, MacLean, Emily L, Cirillo, Daniela, Cobelens, Frank, Gillespie, Stephen H, Kohli, Mikashmi, Ruhwald, Morten, Savic, Rada, Brigden, Grania, Gidado, Mustapha, Goletti, Delia, Hanna, Debra, Hasan, Rumina, Hewison, Cathy, Koura, Kobto G, Lienhardt, Christian, Lungu, Patrick, McHugh, Timothy D, McKenna, Lindsay, Scott, Cherise, Scriba, Thomas, Sekaggya-Wiltshire, Christine, Kasaeva, Tereza, Zignol, Matteo, Denkinger, Claudia M, Falzon, Dennis

“…The World Health Organization has developed target product profiles containing minimum and optimum targets for key characteristics for tests for tuberculosis…”
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Thinking beyond diagnostic accuracy to evaluate tuberculosis screening tests by MacLean, Emily L-H, Yapa, H Manisha

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Activation of Th2 cells downregulates CRTh2 through an NFAT1 mediated mechanism by MacLean Scott, Emily, Solomon, Lauren A, Davidson, Courtney, Storie, Jessica, Palikhe, Nami Shrestha, Cameron, Lisa

“…CRTh2 (encoded by PTGDR2) is a G-protein coupled receptor expressed by Th2 cells as well as eosinophils, basophils and innate lymphoid cells (ILC)2s…”
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The inclusion of children and adolescents in tuberculosis diagnostic development and evaluation–a consensus statement by Bijker, Else M, Horn, Lyn, LaCourse, Sylvia, MacLean, Emily L, Marais, Ben J, Nicol, Mark P, Olbrich, Laura, Seddon, James A, Sutherland, Jayne S, Song, Rinn, Zar, Heather J, Jaganath, Devan

“…The diagnosis of paediatric tuberculosis remains a challenge due to the non-specificity of symptoms and the paucibacillary nature of tuberculosis in children…”
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Subclinical tuberculosis: a meta-analysis of prevalence and scoping review of definitions, prevalence and clinical characteristics by Teo, Alvin Kuo Jing, MacLean, Emily Lai-Ho, Fox, Greg J

“…This scoping review aimed to characterise definitions used to describe subclinical tuberculosis (TB), estimate the prevalence in different populations and…”
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A tuberculosis biomarker database: the key to novel TB diagnostics by Yerlikaya, Seda, Broger, Tobias, MacLean, Emily, Pai, Madhukar, Denkinger, Claudia M

“…Summary New diagnostic innovations for tuberculosis (TB), including point-of-care solutions, are critical to reach the goals of the End TB Strategy. However,…”
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Diagnostic accuracy of point-of-care ultrasound for pulmonary tuberculosis: A systematic review by Bigio, Jacob, Kohli, Mikashmi, Klinton, Joel Shyam, MacLean, Emily, Gore, Genevieve, Small, Peter M, Ruhwald, Morten, Weber, Stefan Fabian, Jha, Saurabh, Pai, Madhukar

“…The advent of affordable, portable ultrasound devices has led to increasing interest in the use of point-of-care ultrasound (POCUS) for the detection of…”
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Tuberculosis treatment monitoring tests during routine practice: study design guidance by MacLean, Emily Lai-Ho, Zimmer, Alexandra J, den Boon, Saskia, Gupta-Wright, Ankur, Cirillo, Daniela M, Cobelens, Frank, Gillespie, Stephen H, Nahid, Payam, Phillips, Patrick P, Ruhwald, Morten, Denkinger, Claudia M

“…The current tools for tuberculosis (TB) treatment monitoring, smear microscopy and culture, cannot accurately predict poor treatment outcomes. Research into…”
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Sandfly Fever Sicilian Virus-Leishmania major co-infection modulates innate inflammatory response favoring myeloid cell infections and skin hyperinflammation by Heirwegh, Ellen, MacLean, Emily, He, Jinlei, Kamhawi, Shaden, Sagan, Selena M., Olivier, Martin

“…Background The leishmaniases are a group of sandfly-transmitted diseases caused by species of the protozoan parasite, Leishmania . With an annual incidence of…”
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Integrated testing for TB and COVID-19 by MacLean, Emily L, Villa-Castillo, Luz, Ruhwald, Morten, Ugarte-Gil, César, Pai, Madhukar

“…Integrated testing for TB and COVID-19 may help find those TB patients who are not accessing care in the context of the COVID-19 pandemic. Some molecular…”
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Integrating tuberculosis and COVID-19 molecular testing in Lima, Peru: a cross-sectional, diagnostic accuracy study by MacLean, Emily Lai-Ho, Villa-Castillo, Luz, Espinoza-Lopez, Patricia, Caceres, Tatiana, Sulis, Giorgia, Kohli, Mikashmi, Pai, Madhukar, Ugarte-Gil, César

“…Integrated molecular testing could be an opportunity to detect and provide care for both tuberculosis and COVID-19. Many high tuberculosis burden countries,…”
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A 10-Gene Signature for the Diagnosis and Treatment Monitoring of Active Tuberculosis Using a Molecular Interaction Network Approach by MacLean, Emily, Broger, Tobias

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Adoption and uptake of the lateral flow urine LAM test in countries with high tuberculosis and HIV/AIDS burden: current landscape and barriers by Singhroy, Diane N., MacLean, Emily, Kohli, Mikashmi, Lessem, Erica, Branigan, David, England, Kathleen, Suleiman, Khairunisa, Drain, Paul K., Ruhwald, Morten, Schumacher, Samuel, Denkinger, Claudia M., Waning, Brenda, Van Gemert, Wayne, Pai, Madhukar

“…Background: Since 2015, the World Health Organization (WHO) has recommended a commercially available lateral-flow urine LAM test (Alere-LAM) to assist in the…”
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Bayesian latent class analysis produced diagnostic accuracy estimates that were more interpretable than composite reference standards for extrapulmonary tuberculosis tests by MacLean, Emily L, Kohli, Mikashmi, Köppel, Lisa, Schiller, Ian, Sharma, Surendra K, Pai, Madhukar, Denkinger, Claudia M, Dendukuri, Nandini

“…Evaluating the accuracy of extrapulmonary tuberculosis (TB) tests is challenging due to lack of a gold standard. Latent class analysis (LCA), a statistical…”
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Accuracy of package inserts of SARS-CoV-2 rapid antigen tests: a secondary analysis of manufacturer versus systematic review data by Bigio, Jacob, MacLean, Emily L-H, Das, Rishav, Sulis, Giorgia, Kohli, Mikashmi, Berhane, Sarah, Dinnes, Jacqueline, Deeks, Jonathan J, Brümmer, Lukas E, Denkinger, Claudia M, Pai, Madhukar

“…Rapid antigen tests (RATs) were crucial during the COVID-19 pandemic. Information provided by the test manufacturer in product package inserts, also known as…”
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Postpartum Haemorrhage Care in Ghana and Uganda: Grounds for Hope and Concern by Maclean, Emily

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Most common reasons for primary care visits in low- and middle-income countries: A systematic review by Bigio, Jacob, MacLean, Emily, Vasquez, Nathaly Aguilera, Huria, Lavanya, Kohli, Mikashmi, Gore, Genevieve, Hannay, Emma, Pai, Madhukar, Adam, Pierrick

“…With the Covid-19 pandemic and the introduction of the WHO's Essential Diagnostics List (EDL), increasing global attention is focused on the crucial role of…”
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