Search Results - "MacKintosh, F C"

Modeling semiflexible polymer networks by Broedersz, C. P., MacKintosh, F. C.

“…Assemblies of semiflexible polymers form the backbone of biological matter. Much stiffer than most synthetic polymers, they form structures with unique…”
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Strain-controlled criticality governs the nonlinear mechanics of fibre networks by Sharma, A., Licup, A. J., Jansen, K. A., Rens, R., Sheinman, M., Koenderink, G. H., MacKintosh, F. C.

“…Fibre networks become rigid at a critical connectivity, but biopolymers giving structure to cells aren’t always well connected. Modelling and experiments on…”
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Origin of Slow Stress Relaxation in the Cytoskeleton by Mulla, Yuval, MacKintosh, F C, Koenderink, Gijsje H

“…Dynamically cross-linked semiflexible biopolymers such as the actin cytoskeleton govern the mechanical behavior of living cells. Semiflexible biopolymers…”
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Broken Detailed Balance of Filament Dynamics in Active Networks by Gladrow, J, Fakhri, N, MacKintosh, F C, Schmidt, C F, Broedersz, C P

“…Myosin motor proteins drive vigorous steady-state fluctuations in the actin cytoskeleton of cells. Endogenous embedded semiflexible filaments such as…”
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Nonequilibrium Mechanics of Active Cytoskeletal Networks by Mizuno, Daisuke, Tardin, Catherine, Schmidt, C.F, MacKintosh, F.C

“…Cells both actively generate and sensitively react to forces through their mechanical framework, the cytoskeleton, which is a nonequilibrium composite material…”
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Nonlinear Poisson Effect Governed by a Mechanical Critical Transition by Shivers, Jordan L, Arzash, Sadjad, MacKintosh, F C

“…Under extensional strain, fiber networks can exhibit an anomalously large and nonlinear Poisson effect accompanied by a dramatic transverse contraction and…”
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Nonlinear elasticity in biological gels by STORM, Comelis, PASTORE, Jennifer J, MACKINTOSH, F. C, LUBENSKY, T. C, JANMEY, Paul A

“…The mechanical properties of soft biological tissues are essential to their physiological function and cannot easily be duplicated by synthetic materials…”
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Elastic Behavior of Cross-Linked and Bundled Actin Networks by Gardel, M. L., Shin, J. H., MacKintosh, F. C., Mahadevan, L., Matsudaira, P., Weitz, D. A.

“…Networks of cross-linked and bundled actin filaments are ubiquitous in the cellular cytoskeleton, but their elasticity remains poorly understood. We show that…”
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Filament-length-controlled elasticity in 3D fiber networks by Broedersz, C P, Sheinman, M, Mackintosh, F C

“…We present a model for disordered 3D fiber networks to study their linear and nonlinear elasticity. In contrast to previous 2D models, these 3D networks with…”
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Anomalous discontinuity at the percolation critical point of active gels by Sheinman, M, Sharma, A, Alvarado, J, Koenderink, G H, MacKintosh, F C

“…We develop a percolation model motivated by recent experimental studies of gels with active network remodeling by molecular motors. This remodeling was found…”
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Fluctuation-stabilized marginal networks and anomalous entropic elasticity by Dennison, M, Sheinman, M, Storm, C, MacKintosh, F C

“…We study the elastic properties of thermal networks of Hookean springs. In the purely mechanical limit, such systems are known to have a vanishing rigidity…”
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Nonlinear Mechanics of Athermal Branched Biopolymer Networks by Rens, R, Vahabi, M, Licup, A. J, MacKintosh, F. C, Sharma, A

“…Naturally occurring biopolymers such as collagen and actin form branched fibrous networks. The average connectivity in branched networks is generally below the…”
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Deformation of cross-linked semiflexible polymer networks by Head, David A, Levine, Alex J, MacKintosh, F C

“…Networks of filamentous proteins play a crucial role in cell mechanics. These cytoskeletal networks, together with various cross-linking and other associated…”
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The Mechanics and Fluctuation Spectrum of Active Gels by Levine, Alex J, MacKintosh, F. C

“…Recent experiments on molecular motor driven in vitro F-Actin networks have found anomalously large strain fluctuations at low frequency. In addition, the…”
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Sheinman, Sharma, and MacKintosh Reply by Sheinman, M, Sharma, A, MacKintosh, F C

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Force fluctuations and polymerization dynamics of intracellular microtubules by Brangwynne, Clifford P, MacKintosh, F.C, Weitz, David A

“…Microtubules are highly dynamic biopolymer filaments involved in a wide variety of biological processes including cell division, migration, and intracellular…”
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Bacteriophage Capsids: Tough Nanoshells with Complex Elastic Properties by Ivanovska, I. L., de Pablo, P. J., Ibarra, B., Sgalari, G., MacKintosh, F. C., Carrascosa, J. L., Schmidt, C. F., Wuite, G. J. L., Lubensky, Tom C.

“…The shell of bacteriophages protects the viral DNA during host-to-host transfer and serves as a high-pressure container storing energy for DNA injection into a…”
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Elastic regimes of subisostatic athermal fiber networks by Licup, A J, Sharma, A, MacKintosh, F C

“…Athermal models of disordered fibrous networks are highly useful for studying the mechanics of elastic networks composed of stiff biopolymers. The underlying…”
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Effective medium theory of semiflexible filamentous networks by Das, Moumita, MacKintosh, F C, Levine, Alex J

“…We develop an effective medium approach to the mechanics of disordered, semiflexible polymer networks and study the response of such networks to uniform and…”
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Deformation and collapse of microtubules on the nanometer scale by de Pablo, P J, Schaap, I A T, MacKintosh, F C, Schmidt, C F

“…We probe the local mechanical properties of microtubules at the nanometer scale by radial indentation with a scanning force microscope tip. We find a linear…”
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