Search Results - "MacKenzie, Laurie"

A Strategy for Identifying Novel, Mechanistically Unique Inhibitors of Topoisomerase I by Hecht, Sidney M, Berry, David E, MacKenzie, Laurie J, Busby, Robert W, Nasuti, Christopher A

“…While the design of molecules that inhibit or antagonize the functions of specific macromolecules is now well precedented, in many cases the structural…”
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Selective Inhibition of Aβ Fibril Formation by Wood, Stephen J., MacKenzie, Lauri, Maleeff, Beverly, Hurle, Mark R., Wetzel, Ronald

“…We describe here an inhibitor of in vitro fibril formation, hexadecyl-N-methylpiperidinium (HMP) bromide, which is selective for the Alzheimer's disease…”
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Differential radioprotection of normal tissues by hydrophilic chemical protectors by Brown, D Q, Yuhas, J M, MacKenzie, L J, Graham, 3rd, W J, Pittock, 3rd, J W

“…Analogous to certain radiosensitizers which are too hydrophilic to enter tumor cells, certain radioprotectors, because of their hydrophilicity, may also be…”
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Take-Away: The Production and Consumption of Service Journalism by Mackenzie, Laurie J

“…This thesis argues that service journalism is a distinct form of journalism with identifiable components that has evolved largely within the context of women's…”
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Naturally occurring inhibitors of topoisomerase I mediated DNA relaxation by Berry, David E, MacKenzie, Laurie, Shultis, Elva A, Chan, James A, Hecht, Sidney M

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Can WR-2721 be improved upon? by Brown, D Q, Graham, 3rd, W J, MacKenzie, L J, Pittock, 3rd, J W, Shaw, L M

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9-Octadecynoic acid: a novel DNA binding agent by Berry, David E, Chan, James A, MacKenzie, Laurie, Hecht, Sidney M

“…A novel bioassay was developed to permit the identification of cytotoxic natural principles that bind to DNA. A hexane extract of Schoepfia californica…”
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Isolation of cell cycle-dependent gamma ray-sensitive Chinese hamster ovary cell by Stamato, T D, Weinstein, R, Giaccia, A, Mackenzie, L

“…A technique for the isolation of gamma ray-sensitive Chinese hamster ovary (CHO) cell mutants is described, which uses nylon cloth replica plating and…”
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Mutagen treatment of single Chinese hamster ovary cells produces colonies mosaic for glucose-6-phosphate dehydrogenase activity by Stamato, T D, MacKenzie, L, Pagani, J M, Weinstein, R

“…When populations of single Chinesee hamster ovary (CHO) cells were exposed to the mutagen ethyl methane sulfonate (EMS), allowed to grow into colonies, and…”
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Age appropriate by Soonawala, Nash, Dawson, Pamela, MacKenzie, Betts, MacKenzie, Laurie

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Conioidines A and B, Novel DNA-interacting Pyrrolidines from Chamaesaracha conioides by Chan, George W, Berry, David, DeBrosse, Charles W, Houling, Mark E, MacKenzie-LoCasto, Laurie, Offen, Priscilla H, Westley, John W

“…Two novel pyrrolidine compounds, conioidines A [1] and B [2], have been isolated from the Texas plant, Chamaesaracha conioides (Solanaceae). Their structures…”
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