Search Results - "MacKenzie, Erin M"

Exploring life engagement from the perspective of patients with major depressive disorder: a study using patient interviews by Therrien, François, Meehan, Stine R., Weiss, Catherine, Dine, Jennifer, Brown, T. Michelle, MacKenzie, Erin M.

“…Background Patient-reported outcomes can measure health aspects that are meaningful to patients, such as ‘life engagement’ in major depressive disorder (MDD)…”
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Attenuation of the effects of oxidative stress by the MAO-inhibiting antidepressant and carbonyl scavenger phenelzine by Baker, Glen, Matveychuk, Dmitriy, MacKenzie, Erin M., Holt, Andrew, Wang, Yanlin, Kar, Satyabrata

“…Phenelzine (β-phenylethylhydrazine) is a monoamine oxidase (MAO)-inhibiting antidepressant with anxiolytic properties. It possesses a number of important…”
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Effects of Adjunctive Brexpiprazole on Individual Depressive Symptoms and Functioning in Patients With Major Depressive Disorder and Anxious Distress: Post Hoc Analysis of Three Placebo-Controlled Studies by McIntyre, Roger S, Bubolic, Suzy, Zhang, Zhen, MacKenzie, Erin M, Therrien, François, Miguelez, Maia, Boucher, Matthieu

“…Anxiety symptoms in major depressive disorder (MDD) are frequent, and they decrease response to antidepressant treatment (ADT), and affect patient functioning…”
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Efficacy of adjunctive brexpiprazole on symptom clusters of major depressive disorder: A post hoc analysis of four clinical studies by Katzman, Martin A., Therrien, François, MacKenzie, Erin M., Wang, Fan, de Jong-Laird, Anne, Boucher, Matthieu

“…Major depressive disorder (MDD) is a clinically heterogenous condition and its treatment should be individualized according to the presence of particular…”
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Adjunctive Brexpiprazole for Patient Life Engagement in Major Depressive Disorder: A Canadian, Phase 4, Open-Label, Interventional Study: Brexpiprazole d'appoint pour l'engagement dans la vie des patients souffrant de trouble dépressif majeur: une étude interventionnelle canadienne ouverte de phase 4 by Therrien, François, Ward, Caroline, Chokka, Pratap, Habert, Jeffrey, Ismail, Zahinoor, McIntyre, Roger S., MacKenzie, Erin M.

“…Objectives To characterize the effects of adjunctive brexpiprazole on patient life engagement and depressive symptoms in patients with major depressive…”
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Effects of adjunctive brexpiprazole on patient life engagement in major depressive disorder: Post hoc analysis of Inventory of Depressive Symptomatology Self-Report data by McIntyre, Roger S., Therrien, François, Ismail, Zahinoor, Meehan, Stine R., Miguelez, Maia, Larsen, Klaus Groes, Chen, Dalei, MacKenzie, Erin M., Thase, Michael E.

“…Patient-reported outcomes can capture domains that are meaningful to patients, such as life engagement in major depressive disorder (MDD), which reflects life…”
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An update on amine oxidase inhibitors: Multifaceted drugs by Song, Mee-Sook, Matveychuk, Dmitriy, MacKenzie, Erin M., Duchcherer, Maryana, Mousseau, Darrell D., Baker, Glen B.

“…Although not used as extensively as other antidepressants for the treatment of depression, the monoamine oxidase (MAO) inhibitors continue to hold a niche in…”
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The histology of sutures in chicken skulls: Types, conservation, and ontogeny by Arnaout, Bassel, MacKenzie, Erin M., Lantigua, Kayla E., Brzezinski, Kaylen, McKinnell, Iain W., Maddin, Hillary C.

“…Sutures are fibrous joints that occur between bone elements in vertebrate skulls, where they play a variety of roles including facilitating skull growth and…”
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Normal development in Xenopus laevis: A complementary staging table for the skull based on cartilage and bone by MacKenzie, Erin M., Atkins, Jade B., Korneisel, Dana E., Cantelon, Alanna S., McKinnell, Iain W., Maddin, Hillary C.

“…Background Xenopus laevis is a widely used model organism in the fields of genetics and development, and more recently evolution. At present, the most widely…”
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Development of the chicken skull: A complement to the external staging table of Hamburger and Hamilton by Arnaout, Bassel, Lantigua, Kayla E., MacKenzie, Erin M., McKinnell, Iain W., Maddin, Hillary C.

“…Embryonic staging tables provide a standard of developmental stages that can be used by individual investigators and provide approximate time points for the…”
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Overview of the Neuroprotective Effects of the MAO-Inhibiting Antidepressant Phenelzine by Matveychuk, Dmitriy, MacKenzie, Erin M., Kumpula, David, Song, Mee-Sook, Holt, Andrew, Kar, Satyabrata, Todd, Kathryn G., Wood, Paul L., Baker, Glen B.

“…Phenelzine (PLZ) is a monoamine oxidase (MAO)-inhibiting antidepressant with anxiolytic properties. This multifaceted drug has a number of pharmacological and…”
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Quantification of l-stepholidine in rat brain and plasma by high performance liquid chromatography combined with fluorescence detection by Odontiadis, John, MacKenzie, Erin M., Natesan, Sridhar, Mamo, David, Kapur, Shitij, Baker, Glen B.

“…A sensitive and reliable assay for the quantification of l-stepholidine (SPD) in rat plasma and brain was developed using high performance liquid…”
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Monoamine oxidase inhibitors and neuroprotection: a review by Al-Nuaimi, Saleem K, Mackenzie, Erin M, Baker, Glen B

“…Monoamine oxidase inhibitors have been available for more than 50 years, initially developed as antidepressants but currently used in a variety of psychiatric…”
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Inhibition of p53 attenuates ischemic stress-induced activation of astrocytes by Ahn, Kee-Chan, MacKenzie, Erin M, Learman, Cameron R, Hall, Tia C, Weaver, Charles L, Dunbar, Gary L, Song, Mee-Sook

“…In cerebral ischemia, studies of cell death have focused primarily on neurons, but recent work indicates that ischemia also causes damage to astrocytes…”
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The pharmacology and formulation of paliperidone extended release by Chue, Pierre S, MacKenzie, Erin M, Chue, James A, Baker, Glen B

“…Paliperidone, or 9-hydroxyrisperidone (Invega(®), Janssen, Antwerp, Belgium) is the major active metabolite of the atypical antipsychotic risperidone…”
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D-serine and schizophrenia: an update by Nunes, Emerson A, MacKenzie, Erin M, Rossolatos, David, Perez-Parada, Jorge, Baker, Glen B, Dursun, Serdar M

“…Considering the lengthy history of pharmacological treatment of schizophrenia, the development of novel antipsychotic agents targeting the glutamatergic system…”
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Comparison of phenelzine and geometric isomers of its active metabolite, β-phenylethylidenehydrazine, on rat brain levels of amino acids, biogenic amine neurotransmitters and methylamine by Matveychuk, Dmitriy, Nunes, Emerson, Ullah, Nasir, Velázquez-Martinez, Carlos A., MacKenzie, Erin M., Baker, Glen B.

“…Phenelzine is a monoamine oxidase (MAO) inhibitor used in treatment of depression and anxiety disorders. It also elevates brain levels of γ-aminobutyric acid…”
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The relevance of neuroactive steroids in schizophrenia, depression, and anxiety disorders by MacKenzie, Erin M, Odontiadis, John, Le Mellédo, Jean-Michel, Prior, Trevor I, Baker, Glen B I

“…1. Neuroactive steroids are steroid hormones that exert rapid, nongenomic effects at ligand-gated ion channels. There is increasing awareness of the possible…”
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Phenelzine Causes an Increase in Brain Ornithine that is Prevented by Prior Monoamine Oxidase Inhibition by MacKenzie, Erin M., Grant, Suzanne L., Baker, Glen B., Wood, Paul L.

“…Phenelzine (PLZ), a nonselective irreversible inhibitor of monoamine oxidase (MAO), also inhibits GABA-transaminase (GABA-T), markedly increasing brain GABA…”
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Cardiac risk and schizophrenia by Jindal, Ripu, MacKenzie, Erin M, Baker, Glen B, Yeragani, Vikram K

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