Search Results - "MacKay, G. M."

Tryptophan metabolism and oxidative stress in patients with Huntington's disease by Stoy, N., Mackay, G. M., Forrest, C. M., Christofides, J., Egerton, M., Stone, T. W., Darlington, L. G.

“…Abnormalities in the kynurenine pathway may play a role in Huntington's disease (HD). In this study, tryptophan depletion and loading were used to investigate…”
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Comparable rates of secondary surgery between anterior cruciate ligament repair with suture tape augmentation and anterior cruciate ligament reconstruction by Hopper, G. P., Wilson, W. T., O’Donnell, L., Hamilton, C., Blyth, M. J. G., MacKay, G. M.

“…Purpose The aim of this study was to determine the frequency of secondary surgery following anterior cruciate ligament (ACL) repair with suture tape…”
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Tryptophan metabolism and oxidative stress in patients with chronic brain injury by Mackay, G. M., Forrest, C. M., Stoy, N., Christofides, J., Egerton, M., Stone, T. W., Darlington, L. G.

“…The kynurenine pathway generates the excitotoxic N‐methyl‐d‐aspartate receptor agonist, quinolinic acid and the glutamate antagonist, kynurenic acid, as well…”
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Blood 5‐hydroxytryptamine, 5‐hydroxyindoleacetic acid and melatonin levels in patients with either Huntington's disease or chronic brain injury by Christofides, J., Bridel, M., Egerton, M., Mackay, G. M., Forrest, C. M., Stoy, N., Darlington, L. G., Stone, T. W.

“…Following a study of oxidative tryptophan metabolism to kynurenines, we have now analysed the blood of patients with either Huntington's disease or traumatic…”
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Anterior cruciate ligament repair with internal brace augmentation: A systematic review by Wilson, W.T., Hopper, G.P., Banger, M.S., Blyth, M.J.G., Riches, P.E., MacKay, G.M.

“…•Proximal ACL tears have the most potential for healing after primary repair.•ACL repair with internal bracing has satisfactory outcomes in individual cohort…”
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Tryptophan loading induces oxidative stress by Forrest, C M, Mackay, G M, Stoy, N, Egerton, M, Christofides, J, Stone, T W, Darlington, L G

“…In previous studies tryptophan loads have been administered to human subjects in order to raise central levels of 5-hydroxytryptamine (5HT) and assess the…”
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Altered kynurenine metabolism correlates with infarct volume in stroke by Darlington, L. G., Mackay, G. M., Forrest, C. M., Stoy, N., George, C., Stone, T. W.

“…Inflammation and oxidative stress are involved in brain damage following stroke, and tryptophan oxidation along the kynurenine pathway contributes to the…”
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Deficits in muscle strength are not seen following recovery from augmented primary repair of anterior cruciate ligament tears by Wilson, W T, Banger, M S, Hopper, G P, Blyth, M J G, MacKay, G M, Riches, P E

“…Anterior cruciate ligament (ACL) repair for proximal tears, where the ligament is re-attached and augmented with suture tape, can negate the need for graft…”
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Tryptophan, adenosine, neurodegeneration and neuroprotection by Stone, T W, Forrest, C M, Mackay, G M, Stoy, N, Darlington, L G

“…This review summarises the potential contributions of two groups of compounds to cerebral dysfunction and damage in metabolic disease. The kynurenines are…”
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How drivers sit in cars by Parkin, S., Mackay, G.M., Cooper, A.

“…This paper presents results from a study to measure the separation of the driver's head and shoulder to various internal features of the car. Drivers were…”
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Venepuncture: the medicolegal hazards by McConnell, A. A., Mackay, G. M.

“…Venepuncture is commonly regarded as a trivial procedure allocated to the most junior medical staff. The result of this policy is that junior doctors are…”
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Restrained occupants on the nonstruck side in lateral collisions by Mackay, G M, Hill, J, Parkin, S, Munns, J A

“…Of injury-producing collisions with high seat belt use, some 25% to 30% are lateral collisions. This paper describes some of the characteristics of those…”
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Chest and abdominal injuries caused by seat belt loading by Hill, J R, Mackay, G M, Morris, A P

“…Injuries will inevitably occur when restraining loads are exerted on a car occupant by a seat belt during a crash. This study investigated the nature,…”
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Multiple pathology related to occupation in an elderly obese seasonal migrant worker by McConnell, A A, MacKay, G M

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Maxillofacial injuries following steering wheel contact by drivers using seat belts by Rogers, S, Hill, J R, Mackay, G M

“…Maxillofacial injuries are common sequelae in road traffic accidents. For the restrained driver, impact against the steering wheel is the most prevalent cause…”
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Restrained front seat car occupant fatalities--the nature and circumstances of their injuries by Mackay, G M, Cheng, L, Smith, M, Parkin, S

“…The circumstances of a rural and urban sample of fatalities in vehicles less than six years old is described. The data originate from an in-depth,…”
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Purine Metabolism and Clinical Status of Patients with Rheumatoid Arthritis Treated with Dipyridamole by Forrest, C. M., Stone, T. W., Mackay, G. M., Oxford, L., Stoy, N., Harman, G., Darlington, L. G.

“…The anti-inflammatory activities of methotrexate and sulphasalazine may be mediated by increases in endogenous adenosine levels. Since the vascular protective…”
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Consent in medicine and sport by McConnell, A A, Mackay, G M

“…Last year's football World Cup serves to highlight the confusion now surrounding the classical aim of both sport and sports medicine, namely a healthy mind in…”
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Medical Confidentiality in Sport and the Public Interest by McConnell, A A, MacKay, M G

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The Limitations Of Current Seatbelts In Europe--Some Population Considerations by Mackay, G. M., Hill, J. R.

“…Seatbelts are most likely to function as they were designed if the car occupants' survival space remains uncompromised during an impact. Crashed cars with…”
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