Search Results - "MacIsaac, R"

clinical significance of hyperfiltration in diabetes by Jerums, G, Premaratne, E, Panagiotopoulos, S, MacIsaac, R. J

“…Glomerular filtration rate is commonly elevated in early diabetes and patients with this symptom are arbitrarily considered to have hyperfiltration. The…”
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Systematic review and meta-analysis of prevalence of sarcopenia in post acute inpatient rehabilitation by Churilov, I., Churilov, L., MacIsaac, R. J., Ekinci, E. I.

“…Summary : Sarcopenia is associated with poor function and increased risk of falls and disability. This work reports a systematic review and meta-analysis of…”
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Investigating the efficacy of baricitinib in new onset type 1 diabetes mellitus (BANDIT)-study protocol for a phase 2, randomized, placebo controlled trial by Waibel, M, Thomas, H E, Wentworth, J M, Couper, J J, MacIsaac, R J, Cameron, F J, So, M, Krishnamurthy, B, Doyle, M C, Kay, T W

“…Type 1 diabetes (T1D) places an extraordinary burden on individuals and their families, as well as on the healthcare system. Despite recent advances in glucose…”
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The impact of hyperfiltration on the diabetic kidney by Premaratne, E, Verma, S, Ekinci, E.I, Theverkalam, G, Jerums, G, MacIsaac, R.J

“…Abstract More than two decades ago, hyperfiltration (HF) in diabetes was postulated to be a maladaptive response observed early in the course of diabetic…”
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Clinicians feel comfortable discussing alcohol but not illicit drug use with young adults with Type 1 diabetes: a survey of clinicians by Pastor, A., Conn, J., O'Brien, C. L., Teng, J., Loh, M., Collins, L, MacIsaac, R. J., Bonomo, Y.

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A tale of two sisters - delayed diagnosis of genetic hyperinsulinaemic hypoglycaemia by Stringer, F, Preston, C, MacIsaac, R, Inchley, F, Rivera-Woll, L, Farrell, S, Sachithanandan, N

“…Congenital hyperinsulinism is the leading cause of persistent hypoglycaemia in infants and children; however, it is uncommon to be diagnosed in adulthood. We…”
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Evaluation of the diagnostic performance of the creatinine‐based Chronic Kidney Disease Epidemiology Collaboration equation in people with diabetes: A systematic review by Zafari, N., Churilov, L., Wong, L. Y.‐L., Lotfaliany, M., Hachem, M., Kiburg, K. V., Kong, L., Torkamani, N., Baxter, H., MacIsaac, R. J., Ekinci, E. I.

“…Aims GFR estimated with the creatinine‐based Chronic Kidney Disease Epidemiology Collaboration (CKD‐EPICr) equation is used to screen for diabetic kidney…”
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Renal hyperfiltration in type 2 diabetes: effect of age-related decline in glomerular filtration rate by Premaratne, E, MacIsaac, R. J, Tsalamandris, C, Panagiotopoulos, S, Smith, T, Jerums, G

“…Aims/hypothesis We sought to characterise the effect of the age-related decline of GFR on hyperfiltration in type 2 diabetes and to identify clinical…”
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Impact of type 2 diabetes on hospitalization and mortality in people with malignancy by Kiburg, K. V., Ward, G. M., Vogrin, S., Steele, K., Mulrooney, E., Loh, M., McLachlan, S. A., Sundararajan, V., MacIsaac, R. J.

“…Aim To compare the characteristics of and outcomes for people with malignancies with and without a co‐diagnosis of diabetes. Methods Emergency department and…”
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Diabetes and higher HbA1c levels are independently associated with adverse renal outcomes in inpatients following multiple hospital admissions by Torkamani, N., Churilov, L., Robbins, R., Jerums, G., Beik, V., Radcliffe, N., Patterson, S., Bellomo, R., Burns, J., Hart, G.K., Lam, Q., Power, D.A., MacIsaac, RJ, Johnson, D.F., Zajac, J., Ekinci, E.I.

“…To assess the association between glycaemic status prior to the first hospital presentation with developing adverse renal outcomes overtime in patients with…”
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Cardiovascular outcomes with antihypertensive therapy in type 2 diabetes: an analysis of intervention trials by Jerums, G, Panagiotopoulos, S, Ekinci, E, MacIsaac, R J

“…In studies of antihypertensive therapy, relative cardiovascular (CV) risk reduction is largely independent of attained systolic blood pressure (SBP). How this…”
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Systemic mastocytosis identified in two women developing fragility fractures during lactation by Zhu, J. J., Mahendran, D., Lee, M. H., Seah, J., Fourlanos, S., Varadarajan, S., Ghasem-Zadeh, A., MacIsaac, R. J., Seeman, E.

“…Two women presenting with fragility fractures during lactation had bone mineral density (BMD) reduced more greatly than usually associated with lactation. The…”
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New approaches for the evaluation of renal vascular function in diabetes by Jerums, G., MacIsaac, R. J.

“…In this issue of Diabetologia, two new approaches are described for the assessment of intra-renal blood flow in people with diabetes. The first approach used…”
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Estimating glomerular filtration rate in diabetes : a comparison of cystatin-C- and creatinine-based methods by MACLSAAC, R. J, TSALAMANDRIS, C, JERUMS, G, THOMAS, M. C, PREMARATNE, E, PANAGIOTOPOULOS, S, SMITH, T. J, POON, A, JENKINS, M. A, RATNAIKE, S. I, POWER, D. A

“…We compared the predictive performance of a GFR based on serum cystatin C levels with commonly used creatinine-based methods in subjects with diabetes. In a…”
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Decrease in serum potassium levels post saline suppression test in primary aldosteronism: an under-recognised phenomenon? by Lee, M H, Moxey, J E, Derbyshire, M M, Ward, G M, MacIsaac, R J, Sachithanandan, N

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Asymmetric changes in circulating insulin levels after an increase compared with a reduction in insulin pump basal rate in people with Type 1 diabetes by McAuley, S. A., Ward, G. M., Horsburgh, J. C., Gooley, J. L., Jenkins, A. J., MacIsaac, R. J., O'Neal, D. N.

“…Aims To investigate circulating insulin profiles after a clinically relevant insulin pump basal rate increase vs a reduction, and the associated glucose…”
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Combining cutaneous silent periods with quantitative sudomotor axon reflex testing in the assessment of diabetic small fiber neuropathy by Kamel, J.T, Vogrin, S.J, Knight-Sadler, R.J, Willems, N.K, Seiderer, L, Cook, M.J, MacIsaac, R.J, Roberts, L.J

“…Highlights • Routine electrophysiological testing cannot assess small nerve fiber types (Aδ and C). These fibers are commonly affected earlier in diabetic…”
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Bilirubin concentration is positively associated with haemoglobin concentration and inversely associated with albumin to creatinine ratio among Indigenous Australians: eGFR Study by Hughes, J.T., Barzi, F., Hoy, W.E., Jones, G.R.D., Rathnayake, G., Majoni, S.W., Thomas, M.A.B., Sinha, A., Cass, A., MacIsaac, R.J., O'Dea, K., Maple-Brown, L.J.

“…Low serum bilirubin concentrations are reported to be strongly associated with cardio-metabolic disease, but this relationship has not been reported among…”
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Cross‐sectional associations of albuminuria among Aboriginal and Torres Strait Islander adults: the eGFR Study by Hughes, JT, Maple‐Brown, LJ, Thomas, M, Lawton, PD, Sinha, A, Cass, A, Barzi, F, Jones, GRD, Jerums, G, MacIsaac, RJ, O'Dea, K, Hoy, WE

“…ABSTRACT Objective To describe the detailed associations of albuminuria among a contemporary cohort of Aboriginal and Torres Strait Islander people to inform…”
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Elevated iron indices in patients with diabetes by Thomas, M. C., MacIsaac, R. J., Tsalamandris, C., Jerums, George

“…Aims  Excess iron has been implicated in the pathogenesis of diabetes and its complications. This study documents the assessment of plasma iron indices and the…”
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