Search Results - "MacGregor, R."

Effects of environmental variation during seed production on seed dormancy and germination by Penfield, Steven, MacGregor, Dana R.

“…The environment during seed production has major impacts on the behaviour of progeny seeds. It can be shown that for annual plants temperature perception over…”
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A VEL3 histone deacetylase complex establishes a maternal epigenetic state controlling progeny seed dormancy by Chen, Xiaochao, MacGregor, Dana R., Stefanato, Francesca L., Zhang, Naichao, Barros-Galvão, Thiago, Penfield, Steven

“…Mother plants play an important role in the control of dormancy and dispersal characters of their progeny. In Arabidopsis seed dormancy is imposed by the…”
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Maternal temperature history activates Flowering Locus T in fruits to control progeny dormancy according to time of year by Chen, Min, MacGregor, Dana R., Dave, Anuja, Florance, Hannah, Moore, Karen, Paszkiewicz, Konrad, Smirnoff, Nicholas, Graham, Ian A., Penfield, Steven

“…Seasonal behavior is important for fitness in temperate environments but it is unclear how progeny gain their initial seasonal entrainment. Plants use…”
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Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer’s disease by Forner, Stefania, Kawauchi, Shimako, Balderrama-Gutierrez, Gabriela, Kramár, Enikö A., Matheos, Dina P., Phan, Jimmy, Javonillo, Dominic I., Tran, Kristine M., Hingco, Edna, da Cunha, Celia, Rezaie, Narges, Alcantara, Joshua A., Baglietto-Vargas, David, Jansen, Camden, Neumann, Jonathan, Wood, Marcelo A., MacGregor, Grant R., Mortazavi, Ali, Tenner, Andrea J., LaFerla, Frank M., Green, Kim N.

“…Mouse models of human diseases are invaluable tools for studying pathogenic mechanisms and testing interventions and therapeutics. For disorders such as…”
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Contribution of a bonded scholarship scheme to staffing rural health facilities by MacGregor, R G, Ross, A J

“…\r\nBackground\r\nLocal and international research has identified rural origin as an important reason why healthcare professionals (HCPs) work in rural areas,…”
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Small rat islets are superior to large islets in in vitro function and in transplantation outcomes by MacGregor, R R, Williams, S J, Tong, P Y, Kover, K, Moore, W V, Stehno-Bittel, L

“…Barriers to the use of islet transplantation as a practical treatment for diabetes include the limited number of available donor pancreata. This project was…”
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Genetic variation of Amaranthus retroflexus L. and Chenopodium album L. (Amaranthaceae) suggests multiple independent introductions into Iran by Hamidzadeh Moghadam, Shiva, Alebrahim, Mohammad Taghi, Mohebodini, Mehdi, MacGregor, Dana R

“…L. and L. (Amaranthaceae) are weedy plants that cause severe ecological and economic damage. In this study, we collected DNA from three different countries and…”
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Association between chorionicity and preterm birth in twin pregnancies: a systematic review involving 29 864 twin pregnancies by Marleen, S, Dias, C, Nandasena, R, MacGregor, R, Allotey, J, Aquilina, J, Khalil, A, Thangaratinam, S

“…Background The perinatal mortality and morbidity among twins vary by chorionicity. Although it is considered that monochorionicity is associated with an…”
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Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease by Javonillo, Dominic I, Tran, Kristine M, Phan, Jimmy, Hingco, Edna, Kramár, Enikö A, da Cunha, Celia, Forner, Stefania, Kawauchi, Shimako, Milinkeviciute, Giedre, Gomez-Arboledas, Angela, Neumann, Jonathan, Banh, Crystal E, Huynh, Michelle, Matheos, Dina P, Rezaie, Narges, Alcantara, Joshua A, Mortazavi, Ali, Wood, Marcelo A, Tenner, Andrea J, MacGregor, Grant R, Green, Kim N, LaFerla, Frank M

“…Animal models of disease are valuable resources for investigating pathogenic mechanisms and potential therapeutic interventions. However, for complex disorders…”
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Mouse mtDNA mutant model of Leber hereditary optic neuropathy by Lin, Chun Shi, Sharpley, Mark S, Fan, Weiwei, Waymire, Katrina G, Sadun, Alfredo A, Carelli, Valerio, Ross-Cisneros, Fred N, Baciu, Peter, Sung, Eric, McManus, Meagan J, Pan, Billy X, Gil, Daniel W, MacGregor, Grant R, Wallace, Douglas C

“…An animal model of Leber hereditary optic neuropathy (LHON) was produced by introducing the human optic atrophy mtDNA ND6 P25L mutation into the mouse. Mice…”
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Stemmed DNA nanostructure for the selective delivery of therapeutics by Jin, H, Kim, M G, Ko, S B, Kim, D H, Lee, B J, Macgregor, Jr, R B, Shim, G, Oh, Y K

“…DNA has emerged as a biocompatible biomaterial that may be considered for various applications. Here, we report tumor cell-specific aptamer-modified DNA…”
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A Mouse Model of Mitochondrial Disease Reveals Germline Selection against Severe mtDNA Mutations by Fan, Weiwei, Waymire, Katrina G., Narula, Navneet, Li, Peng, Rocher, Christophe, Coskun, Pinar E., Vannan, Mani A., Narula, Jagat, MacGregor, Grant R., Wallace, Douglas C.

“…The majority of mitochondrial DNA (mtDNA) mutations that cause human disease are mild to moderately deleterious, yet many random mtDNA mutations would be…”
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Throughput rates and time to completion of health science students of rural origin in South Africa by MacGregor, R G, Ross, A J

“…\r\nBackground\r\nThere is a shortage of qualified healthcare workers in South Africa (SA), as well as a maldistribution between urban and rural areas…”
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Exploring the pleiotropy of hos1 by MacGregor, Dana R., Penfield, Steven

“…Understanding of the roles that HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE 1 (HOS1) plays in the plant’s ability to sense and respond to environmental…”
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Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death by Wei, Michael C., Zong, Wei-Xing, Emily H. -Y. Cheng, Lindsten, Tullia, Panoutsakopoulou, Vily, Ross, Andrea J., Roth, Kevin A., MacGregor, Grant R., Thompson, Craig B., Korsmeyer, Stanley J.

“…Multiple death signals influence mitochondria during apoptosis, yet the critical initiating event for mitochondrial dysfunction in vivo has been unclear. tBID,…”
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Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle by Paterson, Elyse K, Fielder, Thomas J, MacGregor, Grant R, Ito, Shosuke, Wakamatsu, Kazumasa, Gillen, Daniel L, Eby, Victoria, Boissy, Raymond E, Ganesan, Anand K

“…The mechanisms that lead to variation in human skin and hair color are not fully understood. To better understand the molecular control of skin and hair color…”
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Cystatin F attenuates neuroinflammation and demyelination following murine coronavirus infection of the central nervous system by Syage, Amber R, Pachow, Collin, Murray, Kaitlin M, Henningfield, Caden, Fernandez, Kellie, Du, Annie, Cheng, Yuting, Olivarria, Gema, Kawauchi, Shimako, MacGregor, Grant R, Green, Kim N, Lane, Thomas E

“…Cystatin F is a secreted lysosomal cysteine protease inhibitor that has been implicated in affecting the severity of demyelination and enhancing remyelination…”
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Linked circadian outputs control elongation growth and flowering in response to photoperiod and temperature by Seaton, Daniel D, Smith, Robert W, Song, Young Hun, MacGregor, Dana R, Stewart, Kelly, Steel, Gavin, Foreman, Julia, Penfield, Steven, Imaizumi, Takato, Millar, Andrew J, Halliday, Karen J

“…Clock‐regulated pathways coordinate the response of many developmental processes to changes in photoperiod and temperature. We model two of the best‐understood…”
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The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore by Wallace, Douglas C, Kokoszka, Jason E, Waymire, Katrina G, Levy, Shawn E, Sligh, James E, Cai, Jiyang, Jones, Dean P, MacGregor, Grant R

“…A sudden increase in permeability of the inner mitochondrial membrane, the so-called mitochondrial permeability transition, is a common feature of apoptosis…”
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All clinically-relevant blood components transmit prion disease following a single blood transfusion: a sheep model of vCJD by McCutcheon, Sandra, Alejo Blanco, Anthony Richard, Houston, E Fiona, de Wolf, Christopher, Tan, Boon Chin, Smith, Antony, Groschup, Martin H, Hunter, Nora, Hornsey, Valerie S, MacGregor, Ian R, Prowse, Christopher V, Turner, Marc, Manson, Jean C

“…Variant CJD (vCJD) is an incurable, infectious human disease, likely arising from the consumption of BSE-contaminated meat products. Whilst the epidemic…”
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