Search Results - "MacGregor, Heather L"

Molecular Pathways: Evaluating the Potential for B7-H4 as an Immunoregulatory Target by MacGregor, Heather L, Ohashi, Pamela S

“…With the clinical success of CTLA-4 and PD-1 blockade in treating malignancies, there is tremendous interest in finding new ways to augment antitumor responses…”
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High expression of B7-H3 on stromal cells defines tumor and stromal compartments in epithelial ovarian cancer and is associated with limited immune activation by MacGregor, Heather L., Sayad, Azin, Elia, Andrew, Wang, Ben X., Katz, Sarah Rachel, Shaw, Patricia A., Clarke, Blaise A., Crome, Sarah Q., Robert-Tissot, Celine, Bernardini, Marcus Q., Nguyen, Linh T., Ohashi, Pamela S.

“…BackgroundB7-H3 and B7-H4 are highly expressed by many human malignancies making them attractive immunotherapeutic targets. However, their expression patterns…”
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Tumor cell expression of B7-H4 correlates with higher frequencies of tumor-infiltrating APCs and higher CXCL17 expression in human epithelial ovarian cancer by MacGregor, Heather L., Garcia-Batres, Carlos, Sayad, Azin, Elia, Andrew, Berman, Hal K., Toker, Aras, Katz, Sarah Rachel, Shaw, Patricia A., Clarke, Blaise A., Crome, Sarah Q., Robert-Tissot, Celine, Bernardini, Marcus Q., Nguyen, Linh T., Ohashi, Pamela S.

“…B7-H4, an immune suppressive member of the B7 family, is highly expressed in a wide variety of human malignancies making it an attractive immunotherapeutic…”
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372 TAC-T cells persist and remain functional during and after repeated tumor exposure in vitro and in vivo by MacGregor, Heather L, Prosser, Suzanna L, Xu, Stacey X, MacDonald, Kyle, Kadri, Aksha, Randhawa, Ritu R, Shetty, Swati, Pirati, Sailaja, Bhemarasetty, Deepika, Helsen, Christopher W, Sengupta, Sadhak, Bader, Andreas G

“…BackgroundT cell antigen coupler (TAC) is a chimeric receptor that redirects T cells (TAC-T) towards surface-expressed tumor antigens to create safe and…”
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International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study by Pagès, Franck, Mlecnik, Bernhard, Marliot, Florence, Bindea, Gabriela, Ou, Fang-Shu, Bifulco, Carlo, Lugli, Alessandro, Zlobec, Inti, Rau, Tilman T, Berger, Martin D, Nagtegaal, Iris D, Vink-Börger, Elisa, Hartmann, Arndt, Geppert, Carol, Kolwelter, Julie, Merkel, Susanne, Grützmann, Robert, Van den Eynde, Marc, Jouret-Mourin, Anne, Kartheuser, Alex, Léonard, Daniel, Remue, Christophe, Wang, Julia Y, Bavi, Prashant, Roehrl, Michael H A, Ohashi, Pamela S, Nguyen, Linh T, Han, SeongJun, MacGregor, Heather L, Hafezi-Bakhtiari, Sara, Wouters, Bradly G, Masucci, Giuseppe V, Andersson, Emilia K, Zavadova, Eva, Vocka, Michal, Spacek, Jan, Petruzelka, Lubos, Konopasek, Bohuslav, Dundr, Pavel, Skalova, Helena, Nemejcova, Kristyna, Botti, Gerardo, Tatangelo, Fabiana, Delrio, Paolo, Ciliberto, Gennaro, Maio, Michele, Laghi, Luigi, Grizzi, Fabio, Fredriksen, Tessa, Buttard, Bénédicte, Angelova, Mihaela, Vasaturo, Angela, Maby, Pauline, Church, Sarah E, Angell, Helen K, Lafontaine, Lucie, Bruni, Daniela, El Sissy, Carine, Haicheur, Nacilla, Kirilovsky, Amos, Berger, Anne, Lagorce, Christine, Meyers, Jeffrey P, Paustian, Christopher, Feng, Zipei, Ballesteros-Merino, Carmen, Dijkstra, Jeroen, van de Water, Carlijn, van Lent-van Vliet, Shannon, Knijn, Nikki, Mușină, Ana-Maria, Scripcariu, Dragos-Viorel, Popivanova, Boryana, Xu, Mingli, Fujita, Tomonobu, Hazama, Shoichi, Suzuki, Nobuaki, Nagano, Hiroaki, Okuno, Kiyotaka, Torigoe, Toshihiko, Sato, Noriyuki, Furuhata, Tomohisa, Takemasa, Ichiro, Itoh, Kyogo, Patel, Prabhu S, Vora, Hemangini H, Shah, Birva, Patel, Jayendrakumar B, Rajvik, Kruti N, Pandya, Shashank J, Shukla, Shilin N, Wang, Yili, Zhang, Guanjun, Kawakami, Yutaka, Marincola, Francesco M, Ascierto, Paolo A, Sargent, Daniel J, Fox, Bernard A, Galon, Jérôme

“…The estimation of risk of recurrence for patients with colon carcinoma must be improved. A robust immune score quantification is needed to introduce immune…”
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Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer by Mlecnik, Bernhard, Bifulco, Carlo, Bindea, Gabriela, Marliot, Florence, Lugli, Alessandro, Lee, J Jack, Zlobec, Inti, Rau, Tilman T, Berger, Martin D, Nagtegaal, Iris D, Vink-Börger, Elisa, Hartmann, Arndt, Geppert, Carol, Kolwelter, Julie, Merkel, Susanne, Grützmann, Robert, Van den Eynde, Marc, Jouret-Mourin, Anne, Kartheuser, Alex, Léonard, Daniel, Remue, Christophe, Wang, Julia Y, Bavi, Prashant, Roehrl, Michael H A, Ohashi, Pamela S, Nguyen, Linh T, Han, SeongJun, MacGregor, Heather L, Hafezi-Bakhtiari, Sara, Wouters, Bradly G, Masucci, Giuseppe V, Andersson, Emilia K, Zavadova, Eva, Vocka, Michal, Spacek, Jan, Petruzelka, Lubos, Konopasek, Bohuslav, Dundr, Pavel, Skalova, Helena, Nemejcova, Kristyna, Botti, Gerardo, Tatangelo, Fabiana, Delrio, Paolo, Ciliberto, Gennaro, Maio, Michele, Laghi, Luigi, Grizzi, Fabio, Fredriksen, Tessa, Buttard, Bénédicte, Lafontaine, Lucie, Bruni, Daniela, Lanzi, Anastasia, El Sissy, Carine, Haicheur, Nacilla, Kirilovsky, Amos, Berger, Anne, Lagorce, Christine, Paustian, Christopher, Ballesteros-Merino, Carmen, Dijkstra, Jeroen, van de Water, Carlijn, van Lent-van Vliet, Shannon, Knijn, Nikki, Muşină, Ana-Maria, Scripcariu, Dragos-Viorel, Popivanova, Boryana, Xu, Mingli, Fujita, Tomonobu, Hazama, Shoichi, Suzuki, Nobuaki, Nagano, Hiroaki, Okuno, Kiyotaka, Torigoe, Toshihiko, Sato, Noriyuki, Furuhata, Tomohisa, Takemasa, Ichiro, Itoh, Kyogo, Patel, Prabhu S, Vora, Hemangini H, Shah, Birva, Patel, Jayendrakumar B, Rajvik, Kruti N, Pandya, Shashank J, Shukla, Shilin N, Wang, Yili, Zhang, Guanjun, Kawakami, Yutaka, Marincola, Francesco M, Ascierto, Paolo A, Fox, Bernard A, Pagès, Franck, Galon, Jérôme

“…The purpose of this study was to evaluate the prognostic value of Immunoscore in patients with stage III colon cancer (CC) and to analyze its association with…”
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Multicenter International Study of the Consensus Immunoscore for the Prediction of Relapse and Survival in Early-Stage Colon Cancer by Mlecnik, Bernhard, Lugli, Alessandro, Bindea, Gabriela, Marliot, Florence, Bifulco, Carlo, Lee, Jiun-Kae Jack, Zlobec, Inti, Rau, Tilman T, Berger, Martin D, Nagtegaal, Iris D, Vink-Börger, Elisa, Hartmann, Arndt, Geppert, Carol I, Kolwelter, Julie, Merkel, Susanne, Grützmann, Robert, Van den Eynde, Marc, Jouret-Mourin, Anne, Kartheuser, Alex, Léonard, Daniel, Remue, Christophe, Wang, Julia, Bavi, Prashant, Roehrl, Michael H A, Ohashi, Pamela S, Nguyen, Linh T, Han, SeongJun, MacGregor, Heather L, Hafezi-Bakhtiari, Sara, Wouters, Bradly G, Masucci, Giuseppe V, Andersson, Emilia K, Zavadova, Eva, Vocka, Michal, Spacek, Jan, Petruzelka, Lubos, Konopasek, Bohuslav, Dundr, Pavel, Skalova, Helena, Nemejcova, Kristyna, Botti, Gerardo, Tatangelo, Fabiana, Delrio, Paolo, Ciliberto, Gennaro, Maio, Michele, Laghi, Luigi, Grizzi, Fabio, Fredriksen, Tessa, Buttard, Bénédicte, Lafontaine, Lucie, Maby, Pauline, Majdi, Amine, Hijazi, Assia, El Sissy, Carine, Kirilovsky, Amos, Berger, Anne, Lagorce, Christine, Paustian, Christopher, Ballesteros-Merino, Carmen, Dijkstra, Jeroen, van de Water, Carlijn, Vliet, Shannon van Lent-van, Knijn, Nikki, Mușină, Ana-Maria, Scripcariu, Dragos-Viorel, Popivanova, Boryana, Xu, Mingli, Fujita, Tomonobu, Hazama, Shoichi, Suzuki, Nobuaki, Nagano, Hiroaki, Okuno, Kiyotaka, Torigoe, Toshihiko, Sato, Noriyuki, Furuhata, Tomohisa, Takemasa, Ichiro, Patel, Prabhu, Vora, Hemangini H, Shah, Birva, Patel, Jayendrakumar B, Rajvik, Kruti N, Pandya, Shashank J, Shukla, Shilin N, Wang, Yili, Zhang, Guanjun, Kawakami, Yutaka, Marincola, Francesco M, Ascierto, Paolo A, Fox, Bernard A, Pagès, Franck, Galon, Jérôme

“…Background: The prognostic value of Immunoscore was evaluated in Stage II/III colon cancer (CC) patients, but it remains unclear in Stage I/II, and in…”
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Clinical Performance of the Consensus Immunoscore in Colon Cancer in the Asian Population from the Multicenter International SITC Study by Mlecnik, Bernhard, Torigoe, Toshihiko, Bindea, Gabriela, Popivanova, Boryana, Xu, Mingli, Fujita, Tomonobu, Hazama, Shoichi, Suzuki, Nobuaki, Nagano, Hiroaki, Okuno, Kiyotaka, Hirohashi, Yoshihiko, Furuhata, Tomohisa, Takemasa, Ichiro, Patel, Prabhudas, Vora, Hemangini, Shah, Birva, Patel, Jayendrakumar B, Rajvik, Kruti N, Pandya, Shashank J, Shukla, Shilin N, Wang, Yili, Zhang, Guanjun, Yoshino, Takayuki, Taniguchi, Hiroya, Bifulco, Carlo, Lugli, Alessandro, Lee, Jiun-Kae Jack, Zlobec, Inti, Rau, Tilman T, Berger, Martin D, Nagtegaal, Iris D, Vink-Börger, Elisa, Hartmann, Arndt, Geppert, Carol I, Kolwelter, Julie, Merkel, Susanne, Grützmann, Robert, Van den Eynde, Marc, Jouret-Mourin, Anne, Kartheuser, Alex, Léonard, Daniel, Remue, Christophe, Wang, Julia, Bavi, Prashant, Roehrl, Michael H A, Ohashi, Pamela S, Nguyen, Linh T, Han, SeongJun, MacGregor, Heather L, Hafezi-Bakhtiari, Sara, Wouters, Bradly G, Masucci, Giuseppe V, Andersson, Emilia, Zavadova, Eva, Vocka, Michal, Spacek, Jan, Petruzelka, Lubos, Konopasek, Bohuslav, Dundr, Pavel, Skalova, Helena, Nemejcova, Kristyna, Botti, Gerardo, Tatangelo, Fabiana, Delrio, Paolo, Ciliberto, Gennaro, Maio, Michele, Laghi, Luigi, Grizzi, Fabio, Marliot, Florence, Fredriksen, Tessa, Buttard, Bénédicte, Lafontaine, Lucie, Maby, Pauline, Majdi, Amine, Hijazi, Assia, El Sissy, Carine, Kirilovsky, Amos, Berger, Anne, Lagorce, Christine, Paustian, Christopher, Ballesteros-Merino, Carmen, Dijkstra, Jeroen, Van de Water, Carlijn, van Lent-van Vliet, Shannon, Knijn, Nikki, Mușină, Ana-Maria, Scripcariu, Dragos-Viorel, Marincola, Francesco M, Ascierto, Paolo A, Fox, Bernard A, Pagès, Franck, Kawakami, Yutaka, Galon, Jérôme

“…BACKGROUND: In this study, we evaluated the prognostic value of Immunoscore in patients with stage I−III colon cancer (CC) in the Asian population. These…”
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31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): late breaking abstracts by Althammer, Sonja, Higgs, Brandon, Jin, Xiaoping, de Wit, Ronald, Fradet, Yves, Vogelzang, Nicholas J, Choueiri, Toni K, Callahan, Margaret K, Pillai, Rathi N, Chan, Emily, Cojocaru, Gady, Murter, Benjamin M, Azulay, Meir, Chajut, Ayelet, Salomon, Ran, Levine, Zurit, Seiwert, Tanguy, Hurd, Mark, Jaime Rodriguez Canales, Rupp, Levi J, Santoro, Stephen P, Yung-Wu, Chia, Emtage, Peter, Bell, Bryan, Olafsen, Tove, Romero, Jason, Keppler, Jennifer S, Sullivan, Ryan J, Hoshida, Yujin, Mier, James W, Stewart, John, Ernstoff, Marc S, Clark, Joseph I, Atkins, Michael B, Signoretti, Sabina, Milhem, Mohammed M, Akporiaye, Emmanuel, Koguchi, Yoshinobu, Sutcliffe, Kim, Bhardwaj, Nina, Hammerich, Linda, Salazar, Andres, Li, Tianhong, London, Cheryl A, Repasky, Elizabeth A, Schell, Todd D, Messenheimer, David J, Rubinstein, Mark, Andrijauskaite, Kristina, Roell, Marina K, Mkrtichyan, Mikayel, Powell, Steven, Terrell, Andrew, Nowak, Ryan K, Blanchard, Miran, Spanos, William Chad, Wennerberg, Erik, Koelwyn, Graeme, Jones, Lee, Demaria, Sandra, Vandeveer, Amanda, Schlom, Jeffrey, Jewell, Christopher M, McNamara, Michael, Conn, Greg, Shepard, Robert, Jin, Ping, Novik, Yelena, Morrison, Debra, Marincola, Franco M, Galon, Jérôme, Zlobec, Inti, Geppert, Carol, Roehrl, Michael H, Kawakami, Yutaka, Okuno, Kiyotaka, Itoh, Kyogo, Vocka, Michal, Petruzelka, Lubos, Konopasek, Bohuslav, Skalova, Helena, Furuhata, Tomohisa, Takemasa, Ichiro, Angell, Helen, Shukla, Shilin N, Grizzi, Fabio, Laghi, Luigi, Botti, Gerardo, Delrio, Paolo, Cilberto, Gennaro, Rosenblum, Michael, Browning, Erica, Talia, Reneta, Stack, Edward, Dan Tong Jia, Horst, Basil, Fulton, Ross B, Uhlik, Mark, Sims, Jennifer S, Chichili, Gurunadh

“…Biomarkers and Immune MonitoringO1 Combinatorial CD8+ and PD-L1+ cell densities correlate with response and improved survival in non-small cell lung cancer…”
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