Search Results - "MacEwan, G."
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Methamphetamine use: A comprehensive review of molecular, preclinical and clinical findings
Published in Drug and alcohol dependence (01-05-2013)“…Abstract Methamphetamine (MA) is a highly addictive psychostimulant drug that principally affects the monoamine neurotransmitter systems of the brain and…”
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Associations of substance use, psychosis, and mortality among people living in precarious housing or homelessness: A longitudinal, community-based study in Vancouver, Canada
Published in PLoS medicine (06-07-2020)“…Background The "trimorbidity" of substance use disorder and mental and physical illness is associated with living in precarious housing or homelessness. The…”
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Dynamic networks of psychotic symptoms in adults living in precarious housing or homelessness
Published in Psychological medicine (01-10-2022)“…People living in precarious housing or homelessness have higher than expected rates of psychotic disorders, persistent psychotic symptoms, and premature…”
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Cerebral Small Vessel Disease, Risk Factors, and Cognition in Tenants of Precarious Housing
Published in Stroke (1970) (01-11-2020)“…BACKGROUND AND PURPOSE:We aim to describe the burden, characteristics, and cognitive associations of cerebral small vessel disease in a Canadian sample living…”
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Predictors and profiles of treatment non-adherence and engagement in services problems in early psychosis
Published in Schizophrenia research (01-07-2008)“…Abstract Treatment adherence in early psychosis individuals is considered problematic. Some studies have tried to understand reasons for medication…”
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Cognitive profiles and associated structural brain networks in a multimorbid sample of marginalized adults
Published in PloS one (13-06-2019)“…Cognition is impaired in homeless and vulnerably housed persons. Within this heterogeneous and multimorbid group, distinct profiles of cognitive dysfunction…”
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The need for speed : an update on methamphetamine addiction
Published in Journal of psychiatry & neuroscience (01-09-2006)“…The psychostimulant methamphetamine (MA) is a highly addictive drug that has surged in popularity over the last decade in North America. A burgeoning number of…”
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Characterizing Traumatic Brain Injury and Its Association with Losing Stable Housing in a Community-based Sample
Published in Canadian journal of psychiatry (01-03-2022)“…Objective: Traumatic brain injury (TBI) is increasingly recognized as a common and impactful health determinant in homeless and precariously housed…”
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A comparison of psychotic symptoms in subjects with methamphetamine versus cocaine dependence
Published in Psychopharmacology (01-05-2017)“…Rationale The psychostimulant drugs cocaine and methamphetamine are potent indirect dopamine receptor agonists which act through similar but not identical…”
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Rasch analysis of the beck depression inventory in a homeless and precariously housed sample
Published in Psychiatry research (01-08-2023)“…•The BDI satisfies Rasch model expectations after the removal of Item 19 (Weight Loss).•Cognitive and somatic symptoms represent a milder depressive condition,…”
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Effects of eight weeks of atypical antipsychotic treatment on middle frontal thickness in drug-naïve first-episode psychosis patients
Published in Schizophrenia research (01-09-2013)“…Abstract Atypical antipsychotic medications generally maintain or increase gray matter amount and functioning. First-episode psychosis patients have lower gray…”
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The Positive and Negative Syndrome Scale (PANSS): A Three-Factor Model of Psychopathology in Marginally Housed Persons with Substance Dependence and Psychiatric Illness
Published in PloS one (21-03-2016)“…Rates of psychopathology are elevated in marginalized and unstably housed persons, underscoring the need for applicable clinical measures for these…”
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Pain, opioid use, depressive symptoms, and mortality in adults living in precarious housing or homelessness: a longitudinal prospective study
Published in Pain (Amsterdam) (01-11-2022)“…Pain and related consequences could contribute to comorbid illness and premature mortality in homeless and precariously housed persons. We analyzed…”
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Movement disorders associated with substance use in adults living in precarious housing or homelessness
Published in Progress in neuro-psychopharmacology & biological psychiatry (30-08-2023)“…Many individuals living in precarious housing or homelessness have multimorbid illnesses, including substance use, psychiatric, and neurological disorders…”
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Multilayer depressive symptom networks in adults with bodily pain living in precarious housing or homelessness
Published in European archives of psychiatry and clinical neuroscience (01-04-2024)“…Housing insecurity is associated with co-occurring depression and pain interfering with daily activities. Network analysis of depressive symptoms along with…”
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Differential sensitivity of intraindividual variability dispersion and global cognition in the prediction of functional outcomes and mortality in precariously housed and homeless adults
Published in Clinical neuropsychologist (05-03-2024)“…To examine cognitive intraindividual variability (IIV) dispersion as a predictor of everyday functioning and mortality in persons who are homeless or…”
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The Assessment of Symptom Severity and Functional Impairment With DSM-IV Axis V
Published in Psychiatric services (Washington, D.C.) (01-04-2011)“…Objective:The Global Assessment of Functioning scale (GAF) is included as axis V in the DSM-IV multiaxial diagnostic system. The GAF is simple to administer…”
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The Hotel Study: Multimorbidity in a Community Sample Living in Marginal Housing
Published in The American journal of psychiatry (01-12-2013)“…The health of a prospective community sample (N=293) of adults living in single-room occupancy hotels was assessed over nearly 2 years. Mortality was high,…”
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A Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Tolerability of High-Dose Quetiapine in Patients With Persistent Symptoms of Schizophrenia or Schizoaffective Disorder
Published in The journal of clinical psychiatry (01-01-2012)“…Quetiapine is often prescribed at higher than approved doses. We investigated the safety, tolerability, and efficacy of quetiapine > 800 mg/d. A trial was…”
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Using serial position effects to investigate memory dysfunction in homeless and precariously housed persons
Published in Clinical neuropsychologist (17-11-2023)“…Background: Homeless and precariously housed persons exhibit significant memory impairment, but the component processes underlying memory dysfunction have not…”
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