Search Results - "MacDougall, John"

A top to bottom evaluation of IRI 2007 within the polar cap by Themens, David R., Jayachandran, P. Thayyil, Nicolls, Michael J., MacDougall, John W.

“…Monthly median values of ionospheric peak height (hmF2) and density (NmF2), derived from ionosonde measurements at four Canadian High Arctic Ionospheric…”
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Characteristics of GPS TEC variations in the polar cap ionosphere by Watson, Chris, Jayachandran, P. T., MacDougall, John W.

“…This paper presents statistical characteristics (occurrence rate, amplitude, and frequency) of low‐frequency (<100 mHz) variations in total electron content…”
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GPS TEC variations in the polar cap ionosphere: Solar wind and IMF dependence by Watson, Chris, Jayachandran, P. T., MacDougall, John W.

“…This statistical study examines the solar wind dependence of total electron content (TEC) variations arising from mesoscale (tens to hundreds of kilometers)…”
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An Infrared Dye-Conjugated Virus-like Particle for the Treatment of Primary Uveal Melanoma by Kines, Rhonda C, Varsavsky, Isabella, Choudhary, Sanghamitra, Bhattacharya, Debaditya, Spring, Sean, McLaughlin, Roger, Kang, Shin J, Grossniklaus, Hans E, Vavvas, Demetrios, Monks, Stephen, MacDougall, John R, de Los Pinos, Elisabet, Schiller, John T

“…The work outlined herein describes AU-011, a novel recombinant papillomavirus-like particle (VLP) drug conjugate and its initial evaluation as a potential…”
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DPP inhibition alters the CXCR3 axis and enhances NK and CD8+ T cell infiltration to improve anti-PD1 efficacy in murine models of pancreatic ductal adenocarcinoma by Fitzgerald, Allison A, Wang, Shangzi, Agarwal, Veena, Marcisak, Emily F, Zuo, Annie, Jablonski, Sandra A, Loth, Melanie, Fertig, Elana J, MacDougall, John, Zhukovsky, Eugene, Trivedi, Shubhendu, Bhatia, Dimple, O'Neill, Vince, Weiner, Louis M

“…BackgroundPancreatic ductal adenocarcinoma (PDAC) is projected to be the second leading cause of cancer death in the USA by 2030. Immune checkpoint inhibitors…”
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Polar patches: Auroral zone precipitation effects by MacDougall, John, Jayachandran, P. T.

“…We look at patches observed by digital ionosondes in the northern polar cap. These observations show that patches have the following properties. (1) Patches…”
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CR011, a fully human monoclonal antibody-auristatin E conjugate, for the treatment of melanoma by KAM FAI TSE, JEFFERS, Michael, MACDOUGALL, John R, RASTELLI, Luca, HERRMANN, John, GALLO, Michael, GAZIT-BORNSTEIN, Gadi, SENTER, Peter D, MEYER, Damon L, LICHENSTEIN, Henri S, LAROCHELLE, William J, POLLACK, Vincent A, MCCABE, Denise A, SHADISH, Melanie L, KHRAMTSOV, Nikolai V, HACKETT, Craig S, SHENOY, Suresh G, BING KUANG, BOLDOG, Ferenc L

“…PURPOSE: Advanced melanoma is a highly drug-refractory neoplasm representing a significant unmet medical need. We sought to identify melanoma-associated cell…”
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Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model by McCann, Christopher K, Growdon, Whitfield B, Kulkarni-Datar, Kashmira, Curley, Michael D, Friel, Anne M, Proctor, Jennifer L, Sheikh, Hana, Deyneko, Igor, Ferguson, Jeanne A, Vathipadiekal, Vinod, Birrer, Michael J, Borger, Darrell R, Mohapatra, Gayatry, Zukerberg, Lawrence R, Foster, Rosemary, Macdougall, John R, Rueda, Bo R

“…Recent evidence links aberrant activation of Hedgehog (Hh) signaling with the pathogenesis of several cancers including medulloblastoma, basal cell, small cell…”
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Treatment parameters modulating regression of human melanoma xenografts by an antibody-drug conjugate (CR011-vcMMAE) targeting GPNMB by POLLACK, Vincent A, ALVAREZ, Enrique, HAHNE, William F, SENTER, Peter D, JEFFERS, Michael E, LICHENSTEIN, Henri S, LAROCHELLE, William J, KAM FAI TSE, TORGOV, Michael Y, SAM XIE, SHENOY, Suresh G, MACDOUGALL, John R, ARROL, Sharon, HAIHONG ZHONG, GERWIEN, Robert W

“…To investigate the pharmacological properties of the CR011-vcMMAE fully human antibody-drug conjugate (ADC), such as dose titrations, quantitation of the time…”
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Spaced transmitter measurements of medium scale traveling ionospheric disturbances near the equator by MacDougall, John, Abdu, M. A., Batista, Inez, Buriti, Ricardo, Medeiros, A. F., Jayachandran, P. T., Borba, Gilvan

“…The motion of Medium Scale Traveling Ionospheric Disturbances (MSTIDs) was measured for 1 year from the eastern tip of Brazil, about 10° degrees south of the…”
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Recombinant Human FIZZ3/Resistin Stimulates Lipolysis in Cultured Human Adipocytes, Mouse Adipose Explants, and Normal Mice by Ort, Tatiana, Arjona, Anibal A, MacDougall, John R, Nelson, Pam J, Rothenberg, Mark E, Wu, Frank, Eisen, Andrew, Halvorsen, Yuan-Di C

“…Human FIZZ3 (hFIZZ3) was identified as an ortholog of mouse resistin (mResistin), an adipocyte-specific secreted factor linked to insulin resistance in…”
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Longitudinal differences in the equatorial spread F characteristics between Vietnam and Brazil by Hoang, Thai Lan, Abdu, M.A., MacDougall, John, Batista, Inez S.

“…We present the results of a comparative study of the equatorial spread F (ESF) and the F layer critical parameter, the base height of the F layer bottomside (…”
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GPS tomography in the polar cap: comparison with ionosondes and in situ spacecraft data by Pokhotelov, Dimitry, Jayachandran, P. T., Mitchell, Cathryn N., MacDougall, John W., Denton, Michael H.

“…Tomographic 4D reconstructions of ionospheric anomalies appearing in the high-latitude polar cap region are compared with plasma density measurements by…”
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PI3K-δ and PI3K-γ Inhibition by IPI-145 Abrogates Immune Responses and Suppresses Activity in Autoimmune and Inflammatory Disease Models by Winkler, David G., Faia, Kerrie L., DiNitto, Jonathan P., Ali, Janid A., White, Kerry F., Brophy, Erin E., Pink, Melissa M., Proctor, Jennifer L., Lussier, Jennifer, Martin, Christian M., Hoyt, Jennifer G., Tillotson, Bonnie, Murphy, Erin L., Lim, Alice R., Thomas, Brian D., MacDougall, John R., Ren, Pingda, Liu, Yi, Li, Lian-Sheng, Jessen, Katti A., Fritz, Christian C., Dunbar, Joi L., Porter, James R., Rommel, Christian, Palombella, Vito J., Changelian, Paul S., Kutok, Jeffery L.

“…Phosphoinositide-3 kinase (PI3K)-δ and PI3K-γ are preferentially expressed in immune cells, and inhibitors targeting these isoforms are hypothesized to have…”
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Recombinant semaphorin 6A-1 ectodomain inhibits in vivo growth factor and tumor cell line-induced angiogenesis by Dhanabal, Mohanraj, Wu, Frank, Alvarez, Enrique, McQueeney, Kelly D., Jeffers, Mike, MacDougall, John, Boldog, Ferenc L., Hackett, Craig, Shenoy, Suresh, Khramtsov, Nikolai, Weiner, Jami, Lichenstein, Henri S., LaRochelle, William J.

“…The Semaphorins are a large family of transmembrane, GPI-anchored and secreted proteins that play an important role in neuronal and endothelial cell guidance…”
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Remote testing of vitamin D levels across the UK MS population-A case control study by Vickaryous, Nicola, Jitlal, Mark, Jacobs, Benjamin Meir, Middleton, Rod, Chandran, Siddharthan, MacDougall, Niall John James, Giovannoni, Gavin, Dobson, Ruth

“…The association between vitamin D deficiency and multiple sclerosis (MS) is well described. We set out to use remote sampling to ascertain vitamin D status and…”
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IBM's S/390 G5 microprocessor design by Slegel, T.J., Averill, R.M., Check, M.A., Giamei, B.C., Krumm, B.W., Krygowski, C.A., Li, W.H., Liptay, J.S., MacDougall, J.D., McPherson, T.J., Navarro, J.A., Schwarz, E.M., Shum, K., Webb, C.F.

“…The IBM S/390 G5 microprocessor in IBM's newest CMOS mainframe system provides more than twice the performance of the previous generation, the G4. The G5…”
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Sporadic E at cusp latitudes by MacDougall, John W., Jayachandran, P.T.

“…This is a study of the sporadic E (Es) that is observed over a ‘cusp latitude’ station, Cambridge Bay (77° CGM lat.). Es is extremely common in late evening…”
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Contributions of tumor and stromal matrix metalloproteinases to tumor progression, invasion and metastasis by MACDOUGALL, J. R, MATRISIAN, L. M

“…The malignant progression of tumors is driven by the expression of oncogenes and loss of expression of tumor suppressor genes; factors that are intrinsic to…”
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Regional Autonomy and Indigenous Exclusivism in Bali by MacDougall, John, Rawski, Frederick

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