Search Results - "MacDonald, William A"

Long noncoding RNA functionality in imprinted domain regulation by MacDonald, William A, Mann, Mellissa R. W

“…Genomic imprinting is a parent-of-origin dependent phenomenon that restricts transcription to predominantly one parental allele. Since the discovery of the…”
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An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences by Ishak, Charles A., Marshall, Aren E., Passos, Daniel T., White, Carlee R., Kim, Seung J., Cecchini, Matthew J., Ferwati, Sara, MacDonald, William A., Howlett, Christopher J., Welch, Ian D., Rubin, Seth M., Mann, Mellissa R.W., Dick, Frederick A.

“…Repetitive genomic regions include tandem sequence repeats and interspersed repeats, such as endogenous retroviruses and LINE-1 elements. Repressive…”
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Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells by Sachani, Saqib S., Landschoot, Lauren S., Zhang, Liyue, White, Carlee R., MacDonald, William A., Golding, Michael C., Mann, Mellissa R. W.

“…Genomic imprinting is a phenomenon that restricts transcription to predominantly one parental allele. How this transcriptional duality is regulated is poorly…”
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Epigenetic Mechanisms of Genomic Imprinting: Common Themes in the Regulation of Imprinted Regions in Mammals, Plants, and Insects by MacDonald, William A.

“…Genomic imprinting is a form of epigenetic inheritance whereby the regulation of a gene or chromosomal region is dependent on the sex of the transmitting…”
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Compromised fertility disrupts Peg1 but not Snrpn and Peg3 imprinted methylation acquisition in mouse oocytes by Denomme, Michelle M, White, Carlee R, Gillio-Meina, Carolina, Macdonald, William A, Deroo, Bonnie J, Kidder, Gerald M, Mann, Mellissa R W

“…Growth and maturation of healthy oocytes within follicles requires bidirectional signaling and intercellular gap junctional communication. Aberrant endocrine…”
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Surface Dynamics of SiO2-like Films on Polymers Grown by DBD Assisted CVD at Atmospheric Pressure by Premkumar, Peter Antony, Starostin, Sergey A., de Vries, Hindrik, Creatore, Mariadriana, Koenraad, Paul M., MacDonald, William A., van de Sanden, Mauritius C. M.

“…The development of the morphology and surface roughness of amorphous SiO2‐like films, on various polymeric substrates was analyzed by atomic force microscopy…”
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Innovative super-resolution in spatial transcriptomics: a transformer model exploiting histology images and spatial gene expression by Zhao, Chongyue, Xu, Zhongli, Wang, Xinjun, Tao, Shiyue, MacDonald, William A, He, Kun, Poholek, Amanda C, Chen, Kong, Huang, Heng, Chen, Wei

“…Abstract Spatial transcriptomics technologies have shed light on the complexities of tissue structures by accurately mapping spatial microenvironments…”
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Photo‐oxidation of poly(ethylene terephthalate) films intended for photovoltaic backsheet by Horne, Fiona J., Liggat, John J., MacDonald, William A., Sankey, Stephen W.

“…ABSTRACT The photodegradation of 36 μm thick poly(ethylene terephthalate) film under artificial weathering conditions has been investigated. A weatherometer…”
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Differential gene expression in layer 3 pyramidal neurons across 3 regions of the human cortical visual spatial working memory network by Enwright Iii, John F, Arion, Dominique, MacDonald, William A, Elbakri, Rania, Pan, Yinghong, Vyas, Gopi, Berndt, Annerose, Lewis, David A

“…Visual spatial working memory (vsWM) is mediated by a distributed cortical network composed of multiple nodes, including primary visual (V1), posterior…”
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Spatial microniches of IL-2 combine with IL-10 to drive lung migratory TH2 cells in response to inhaled allergen by He, Kun, Xiao, Hanxi, MacDonald, William A., Mehta, Isha, Kishore, Akash, Vincent, Augusta, Xu, Zhongli, Ray, Anuradha, Chen, Wei, Weaver, Casey T., Lambrecht, Bart N., Das, Jishnu, Poholek, Amanda C.

“…The mechanisms that guide T helper 2 (T H 2) cell differentiation in barrier tissues are unclear. Here we describe the molecular pathways driving…”
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The Drosophila homolog of the mammalian imprint regulator, CTCF, maintains the maternal genomic imprint in Drosophila melanogaster by MacDonald, William A, Menon, Debashish, Bartlett, Nicholas J, Sperry, G Elizabeth, Rasheva, Vanya, Meller, Victoria, Lloyd, Vett K

“…CTCF is a versatile zinc finger DNA-binding protein that functions as a highly conserved epigenetic transcriptional regulator. CTCF is known to act as a…”
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Improving Access to Safe Anesthetic Care in Rural and Remote Communities in Affluent Countries by Orser, Beverley A., Wilson, C. Ruth, Rotstein, Alexandra J., Iglesias, Stuart J., Spain, Brian T., Ranganathan, Pavithra, MacDonald, William A., Ng, Victor, O’Leary, Susan, Lafontaine, Alika

“…Inadequate access to anesthesia and surgical services is often considered to be a problem of low- and middle-income countries. However, affluent nations,…”
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Epigenetic regulation of genomic imprinting from germ line to preimplantation by MacDonald, William A., Mann, Mellissa R.W.

“…SUMMARY Genomic imprinting is an epigenetic process that distinguishes parental alleles, resulting in parent‐specific expression of a gene or cluster of genes…”
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Conservation of DNA Methylation Programming Between Mouse and Human Gametes and Preimplantation Embryos by White, Carlee R, MacDonald, William A, Mann, Mellissa R W

“…In mice, assisted reproductive technologies (ARTs) applied during gametogenesis and preimplantation development can result in disruption of genomic imprinting…”
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The Generation of Cloned Drosophila melanogaster by Haigh, Andrew J, MacDonald, William A, Lloyd, Vett K

“…We report here the first successful use of embryonic nuclear transfer to create viable adult Drosophila melanogaster clones. Given the generation time, cost…”
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Atp2c2 Is Transcribed From a Unique Transcriptional Start Site in Mouse Pancreatic Acinar Cells by Fenech, Melissa A., Sullivan, Caitlin M., Ferreira, Lucimar T., Mehmood, Rashid, MacDonald, William A., Stathopulos, Peter B., Pin, Christopher L.

“…Proper regulation of cytosolic Ca2+ is critical for pancreatic acinar cell function. Disruptions in normal Ca2+ concentrations affect numerous cellular…”
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Mesomorphic behaviour in copoly(ester-imide)s of poly(butylene-2,6-naphthalate) (PBN) by Jones, Stephen M., Meehan, Stephen J., Sankey, Stephen W., MacDonald, William A., Colquhoun, Howard M.

“…Copolycondensation of N,N′-bis(4-hydroxybutyl)-biphenyl-3,4,3′,4′-tetracarboxylic diimide at 20 and 25 mol% with bis(4-hydroxybutyl)-2,6-naphthalate produces…”
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A role for chromatin topology in imprinted domain regulation by MacDonald, William A, Sachani, Saqib S, White, Carlee R, Mann, Mellissa R W

“…Recently, many advancements in genome-wide chromatin topology and nuclear architecture have unveiled the complex and hidden world of the nucleus, where…”
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Cocrystalline Copolyimides of Poly(ethylene 2,6-naphthalate) by Meehan, Stephen J, Sankey, Stephen W, Jones, Stephen M, MacDonald, William A, Colquhoun, Howard M

“…Copolycondensation of N,N′-bis­(2-hydroxyethyl)-biphenyl-3,4,3′,4′-tetracarboxylic diimide (5–25 mol %) with bis­(2-hydroxyethyl)-2,6-naphthalate affords a…”
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Structural materials underpinning functional materials: teaching old dogs new tricks by MacDonald, William A

“…‘Structural’ polymers are finding new applications underpinning new technology developments based on functional polymers. This paper discusses the use of…”
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