Search Results - "MacDonald, M. J"

Regulation of insulin secretion: role of mitochondrial signalling by Jitrapakdee, S, Wutthisathapornchai, A, Wallace, J. C, MacDonald, M. J

“…Pancreatic beta cells are specialised endocrine cells that continuously sense the levels of blood sugar and other fuels and, in response, secrete insulin to…”
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Relativistic Electron Streaming Instabilities Modulate Proton Beams Accelerated in Laser-Plasma Interactions by Göde, S, Rödel, C, Zeil, K, Mishra, R, Gauthier, M, Brack, F-E, Kluge, T, MacDonald, M J, Metzkes, J, Obst, L, Rehwald, M, Ruyer, C, Schlenvoigt, H-P, Schumaker, W, Sommer, P, Cowan, T E, Schramm, U, Glenzer, S, Fiuza, F

“…We report experimental evidence that multi-MeV protons accelerated in relativistic laser-plasma interactions are modulated by strong filamentary…”
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Clumped-isotope palaeothermometry and LA-ICP-MS U–Pb dating of lava-pile hydrothermal calcite veins by MacDonald, J. M., Faithfull, J. W., Roberts, N. M. W., Davies, A. J., Holdsworth, C. M., Newton, M., Williamson, S., Boyce, A., John, C. M.

“…Calcite veins are a common product of hydrothermal fluid circulation. Clumped-isotope palaeothermometry is a promising technique for fingerprinting the…”
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Formation of diamonds in laser-compressed hydrocarbons at planetary interior conditions by Kraus, D., Vorberger, J., Pak, A., Hartley, N. J., Fletcher, L. B., Frydrych, S., Galtier, E., Gamboa, E. J., Gericke, D. O., Glenzer, S. H., Granados, E., MacDonald, M. J., MacKinnon, A. J., McBride, E. E., Nam, I., Neumayer, P., Roth, M., Saunders, A. M., Schuster, A. K., Sun, P., van Driel, T., Döppner, T., Falcone, R. W.

“…The effects of hydrocarbon reactions and diamond precipitation on the internal structure and evolution of icy giant planets such as Neptune and Uranus have…”
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Use of Pharmaco-Metabonomics for Early Prediction of Acetaminophen-Induced Hepatotoxicity in Humans by Winnike, J H, Li, Z, Wright, F A, Macdonald, J M, O'Connell, T M, Watkins, P B

“…Achieving the ability to identify individuals who are susceptible to drug‐induced liver injury (DILI) would represent a major advance in personalized medicine…”
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Absolute Equation-of-State Measurement for Polystyrene from 25 to 60 Mbar Using a Spherically Converging Shock Wave by Döppner, T, Swift, D C, Kritcher, A L, Bachmann, B, Collins, G W, Chapman, D A, Hawreliak, J, Kraus, D, Nilsen, J, Rothman, S, Benedict, L X, Dewald, E, Fratanduono, D E, Gaffney, J A, Glenzer, S H, Hamel, S, Landen, O L, Lee, H J, LePape, S, Ma, T, MacDonald, M J, MacPhee, A G, Milathianaki, D, Millot, M, Neumayer, P, Sterne, P A, Tommasini, R, Falcone, R W

“…We have developed an experimental platform for the National Ignition Facility that uses spherically converging shock waves for absolute equation-of-state (EOS)…”
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X-ray Thomson scattering absolute intensity from the f-sum rule in the imaginary-time domain by Dornheim, T., Döppner, T., Baczewski, A. D., Tolias, P., Böhme, M. P., Moldabekov, Zh. A., Gawne, Th, Ranjan, D., Chapman, D. A., MacDonald, M. J., Preston, Th. R., Kraus, D., Vorberger, J.

“…We present a formally exact and simulation-free approach for the normalization of X-ray Thomson scattering (XRTS) spectra based on the f-sum rule of the…”
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Demonstration of X-ray Thomson scattering as diagnostics for miscibility in warm dense matter by Frydrych, S., Vorberger, J., Hartley, N. J., Schuster, A. K., Ramakrishna, K., Saunders, A. M., van Driel, T., Falcone, R. W., Fletcher, L. B., Galtier, E., Gamboa, E. J., Glenzer, S. H., Granados, E., MacDonald, M. J., MacKinnon, A. J., McBride, E. E., Nam, I., Neumayer, P., Pak, A., Voigt, K., Roth, M., Sun, P., Gericke, D. O., Döppner, T., Kraus, D.

“…The gas and ice giants in our solar system can be seen as a natural laboratory for the physics of highly compressed matter at temperatures up to thousands of…”
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Turbulent amplification of magnetic fields in laboratory laser-produced shock waves by Meinecke, J., Doyle, H. W., Miniati, F., Bell, A. R., Bingham, R., Crowston, R., Drake, R. P., Fatenejad, M., Koenig, M., Kuramitsu, Y., C. Kuranz, C., Lamb, D. Q., Lee, D., MacDonald, M. J., Murphy, C. D., Park, H-S., Pelka, A., Ravasio, A., Sakawa, Y., Schekochihin, A. A., Scopatz, A., Tzeferacos, P., Wan, W. C., Woolsey, N. C., Yurchak, R., Reville, B., Gregori, G.

“…The origin of the large magnetic fields observed in the interior of the supernova remnant Cassiopeia A is still unclear. Laboratory experiments of…”
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Liquid Structure of Shock-Compressed Hydrocarbons at Megabar Pressures by Hartley, N J, Vorberger, J, Döppner, T, Cowan, T, Falcone, R W, Fletcher, L B, Frydrych, S, Galtier, E, Gamboa, E J, Gericke, D O, Glenzer, S H, Granados, E, MacDonald, M J, MacKinnon, A J, McBride, E E, Nam, I, Neumayer, P, Pak, A, Rohatsch, K, Saunders, A M, Schuster, A K, Sun, P, van Driel, T, Kraus, D

“…We present results for the ionic structure in hydrocarbons (polystyrene, polyethylene) that were shock compressed to pressures of up to 190 GPa, inducing rapid…”
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Isometric handgrip training lowers blood pressure and increases heart rate complexity in medicated hypertensive patients by Millar, P. J., Levy, A. S., McGowan, C. L., McCartney, N., MacDonald, M. J.

“…Hypertension is characterized by elevated blood pressure (BP) and autonomic dysfunction, both thought to be improved with exercise training. Isometric handgrip…”
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Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes by MacDonald, M. J, Longacre, M. J, Langberg, E.-C, Tibell, A, Kendrick, M. A, Fukao, T, Ostenson, C.-G

“…Aims/hypothesis Glucose-stimulated insulin secretion is defective in patients with type 2 diabetes. We sought to acquire new information about enzymes of…”
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Autonomic recovery following sprint interval exercise by Stuckey, M. I., Tordi, N., Mourot, L., Gurr, L. J., Rakobowchuk, M., Millar, P. J., Toth, R., MacDonald, M. J., Kamath, M. V.

“…The autonomic nervous activity was assessed following supramaximal exercise through heart rate (HR) and blood pressure (BP) variability (HRV and BPV) and…”
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Effects of isometric handgrip protocol on blood pressure and neurocardiac modulation by Millar, P J, MacDonald, M J, McCartney, N

“…Isometric handgrip (IHG) remains a well-studied cardiovascular and autonomic stimulus, however the effects of rhythmic IHG protocols remain largely unknown…”
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Magnetized Disruption of Inertially Confined Plasma Flows by Manuel, M J-E, Sefkow, A B, Kuranz, C C, Rasmus, A M, Klein, S R, MacDonald, M J, Trantham, M R, Fein, J R, Belancourt, P X, Young, R P, Keiter, P A, Pollock, B B, Park, J, Hazi, A U, Williams, G J, Chen, H, Drake, R P

“…The creation and disruption of inertially collimated plasma flows are investigated through experiment, simulation, and analytical modeling. Supersonic plasma…”
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Anomalous two-photon Compton scattering by Kettle, B, Aquila, A, Boutet, S, Bucksbaum, P H, Carini, G, Feng, Y, Gamboa, E, Ghimire, S, Glenzer, S, Hart, P, Hastings, J B, Henighan, T, Hunter, M, Koglin, J, Kozina, M, Liu, H, MacDonald, M J, Trigo, M, Reis, D A, Fuchs, M

“…X-ray free-electron lasers can generate radiation pulses with extreme peak intensities at short wavelengths. This enables the investigation of laser–matter…”
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Endothelial function of young healthy males following whole body resistance training by Rakobowchuk, M, McGowan, C. L, de Groot, P. C, Hartman, J. W, Phillips, S. M, MacDonald, M. J

“…1 Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada; and 2 Department of Physiology, University Medical Center Nijmegen, Nijmegen, The…”
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Impact of shear rate pattern on upper and lower limb conduit artery endothelial function in both spinal cord‐injured and able‐bodied men by Totosy de Zepetnek, J. O., Ditor, D. S., Au, J. S., MacDonald, M. J.

“…New Findings What is the central question of this study? This study addresses the following two central questions. (i) What is the impact of vascular…”
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Cross-sectional and longitudinal relationships between cardiorespiratory fitness and health-related quality of life in primary school children in England: the mediating role of psychological correlates of physical activity by Solera-Sanchez, A, Christian, DL, Beltran-Valls, MR, Adelantado-Renau, M, Martin-Smith, R, MacDonald, MJ, Tyler, R, Fairclough, SJ

“…Aims: The aims were (1) to analyse the cross-sectional and longitudinal associations between children’s cardiorespiratory fitness (CRF) and health-related…”
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Identification of ATP Synthase As a Lipid Peroxide Protein Adduct in Pancreatic Islets From Humans With and Without Type 2 Diabetes Mellitus by MacDonald, M. J, Langberg, E.-C, Tibell, A, Sabat, G, Kendrick, M. A, Szweda, L. I, Ostenson, C. G

“…Context: Most current knowledge of pancreatic islet pathophysiology in diabetes mellitus has come from animal models. Even though islets from humans are…”
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