Search Results - "MacDonald, John K."

C-Reactive Protein, Fecal Calprotectin, and Stool Lactoferrin for Detection of Endoscopic Activity in Symptomatic Inflammatory Bowel Disease Patients: A Systematic Review and Meta-Analysis by Mosli, Mahmoud H, Zou, Guangyong, Garg, Sushil K, Feagan, Sean G, MacDonald, John K, Chande, Nilesh, Sandborn, William J, Feagan, Brian G

“…Persistent disease activity is associated with a poor prognosis in inflammatory bowel disease (IBD). Therefore, monitoring of patients with intent to suppress…”
Get full text

Azathioprine or 6-mercaptopurine for maintenance of remission in Crohn's disease by Chande, Nilesh, Patton, Petrease H, Tsoulis, David J, Thomas, Benson S, MacDonald, John K

“…The therapeutic role of 6-mercaptopurine (6-MP) and azathioprine (AZA) remains controversial due to their perceived relatively slow-acting effect and adverse…”
Get more information

Enteral nutrition for maintenance of remission in Crohn's disease by Akobeng, Anthony K, Zhang, Dongni, Gordon, Morris, MacDonald, John K

“…Prevention of relapse is a major issue in the management of quiescent Crohn's disease (CD). Current therapies (e.g. methotrexate, biologics, 6-mercaptopurine…”
Get more information

Azathioprine or 6-mercaptopurine for maintenance of remission in Crohn's disease by Prefontaine, Eliza, Sutherland, Lloyd R, Macdonald, John K, Cepoiu, Monica

“…The therapeutic role of 6-mercaptopurine and azathioprine remains controversial due to their perceived relatively slow-acting effect and adverse effects. A…”
Get more information

Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis by Timmer, Antje, Patton, Petrease H, Chande, Nilesh, McDonald, John W D, MacDonald, John K

“…Maintenance of remission is a major issue in inflammatory bowel disease. In ulcerative colitis, the evidence for the effectiveness of azathioprine and…”
Get more information

Surgical Treatment of Lymphedema: A Systematic Review and Meta-Analysis of Controlled Trials. Results of a Consensus Conference by Chang, David W., Dayan, Joseph, Greene, Arin K., MacDonald, John K., Masia, Jaume, Mehrara, Babak, Neligan, Peter C., Nguyen, Dung

“…The goal of this consensus conference, sponsored by the American Association of Plastic Surgeons, was to perform a systematic review and meta-analysis of…”
Get full text

Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease by Chande, Nilesh, Tsoulis, David J, MacDonald, John K

“…The results from controlled clinical trials investigating the efficacy of azathioprine and 6-mercaptopurine for the treatment of active Crohn's disease have…”
Get more information

Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis by Timmer, Antje, McDonald, John W D, Tsoulis, David J, Macdonald, John K

“…Maintenance of remission is a major issue in inflammatory bowel disease. In ulcerative colitis, the evidence for the effectiveness of azathioprine and…”
Get more information

Methotrexate for induction of remission in refractory Crohn's disease by McDonald, John W D, Wang, Yongjun, Tsoulis, David J, MacDonald, John K, Feagan, Brian G

“…Although corticosteroids are effective for induction of remission of Crohn's disease, many patients relapse when steroids are withdrawn or become steroid…”
Get more information

Adverse effects of biologics: a network meta-analysis and Cochrane overview by Singh, Jasvinder A, Wells, George A, Christensen, Robin, Tanjong Ghogomu, Elizabeth, Maxwell, Lara, Macdonald, John K, Filippini, Graziella, Skoetz, Nicole, Francis, Damian, Lopes, Luciane C, Guyatt, Gordon H, Schmitt, Jochen, La Mantia, Loredana, Weberschock, Tobias, Roos, Juliana F, Siebert, Hendrik, Hershan, Sarah, Lunn, Michael Pt, Tugwell, Peter, Buchbinder, Rachelle

“…Biologics are used for the treatment of rheumatoid arthritis and many other conditions. While the efficacy of biologics has been established, there is…”
Get more information

Histologic scoring indices for evaluation of disease activity in ulcerative colitis by Mosli, Mahmoud H, Parker, Claire E, Nelson, Sigrid A, Baker, Kenneth A, MacDonald, John K, Zou, G Y, Feagan, Brian G, Khanna, Reena, Levesque, Barrett G, Jairath, Vipul

“…Disease activity can be determined using clinical, endoscopic or histologic criteria in patients with ulcerative colitis (UC). Persistent disease activity is…”
Get more information

Vedolizumab for induction and maintenance of remission in ulcerative colitis by Bickston, Stephen J, Behm, Brian W, Tsoulis, David J, Cheng, Jianfeng, MacDonald, John K, Khanna, Reena, Feagan, Brian G

“…Cellular adhesion molecules play an important role in the pathogenesis of ulcerative colitis, making selective blockade of these molecules a promising…”
Get more information

Methotrexate for induction of remission in ulcerative colitis by Chande, Nilesh, Wang, Yongjun, MacDonald, John K, McDonald, John W D

“…Ulcerative colitis (UC) is a chronic inflammatory bowel disease. Corticosteroids and 5-aminosalicylates are the most commonly used therapies. However, many…”
Get more information

Use of external control arms in immune-mediated inflammatory diseases: a systematic review by Zayadi, Alexa, Edge, Robert, Parker, Claire E, Macdonald, John K, Neustifter, Blue, Chang, Joshua, Zhong, Guowei, Singh, Siddharth, Feagan, Brian G, Ma, Christopher, Jairath, Vipul

“…ObjectivesExternal control arms (ECAs) provide useful comparisons in clinical trials when randomised control arms are limited or not feasible. We conducted a…”
Get full text

Reproducibility of histological assessments of disease activity in UC by Mosli, Mahmoud H, Feagan, Brian G, Zou, Guangyong, Sandborn, William J, D'Haens, Geert, Khanna, Reena, Behling, Cynthia, Kaplan, Keith, Driman, David K, Shackelton, Lisa M, Baker, Kenneth A, MacDonald, John K, Vandervoort, Margaret K, Samaan, Mark A, Geboes, Karel, Valasek, Mark A, Pai, Rish, Langner, Cord, Riddell, Robert, Harpaz, Noam, Sewitch, Maida, Peterson, Michael, Stitt, Larry W, Levesque, Barrett G

“…Histopathology is potentially an important outcome measure in UC. Multiple histological disease activity (HA) indices, including the Geboes score (GS) and…”
Get more information

Optimal Approach to Lobectomy for Non-Small Cell Lung Cancer: Systemic Review and Meta-Analysis by Ng, Calvin S.H., MacDonald, John K., Gilbert, Sebastien, Khan, Ali Z., Kim, Young T., Louie, Brian E., Blair Marshall, M., Santos, Ricardo S., Scarci, Marco, Shargal, Yaron, Fernando, Hiran C.

“…Objective Video-assisted thoracic surgery (VATS) lobectomy was introduced over 25 years ago. More recently, the technique has been modified from a multiport…”
Get full text

Tacrolimus (FK506) for induction of remission in refractory ulcerative colitis by Baumgart, Daniel C, Macdonald, John K, Feagan, Brian

“…There are a limited number of treatment options for patients with refractory ulcerative colitis. Animal models of inflammatory bowel disease and uncontrolled…”
Get more information

Sargramostim (GM‐CSF) for induction of remission in crohn's disease: A cochrane inflammatory bowel disease and functional bowel disorders systematic review of randomized trials by Roth, Lee, MacDonald, John K., McDonald, John W.D., Chande, Nilesh

“…Background: We planned to systematically review the efficacy of sargramostim (granulocyte colony stimulating factor [GM‐CSF]) for remission induction in…”
Get full text

Recommendations for standardizing biopsy acquisition and histological assessment of immune checkpoint inhibitor-associated colitis by Ma, Christopher, Pai, Rish K, Schaeffer, David F, Krell, Jonathan, Guizzetti, Leonardo, McFarlane, Stefanie C, MacDonald, John K, Choi, Won-Tak, Feakins, Roger M, Kirsch, Richard, Lauwers, Gregory Y, Pai, Reetesh K, Rosty, Christophe, Srivastava, Amitabh, Walsh, Joanna C., Feagan, Brian G, Jairath, Vipul

“…Immune checkpoint inhibitor-associated colitis (ICIC) affects approximately 15% of cancer patients treated with immunotherapy. Although histological evaluation…”
Get full text

Individualized Venous Thromboembolism Risk Stratification Using the 2005 Caprini Score to Identify the Benefits and Harms of Chemoprophylaxis in Surgical Patients: A Meta-analysis by Pannucci, Christopher J, Swistun, Lukasz, MacDonald, John K, Henke, Peter K, Brooke, Benjamin S

“…OBJECTIVE:We performed a meta-analysis to investigate benefits and harms of chemoprophylaxis among surgical patients individually risk stratified for venous…”
Get full text