Search Results - "MacDonald, I."

A review of recent evidence relating to sugars, insulin resistance and diabetes by Macdonald, I. A.

“…The potential impact on health of diets rich in free sugars, and particularly fructose, is of major concern. The focus of this review is the impact of these…”
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Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production by Brynildsen, Mark P, Winkler, Jonathan A, Spina, Catherine S, MacDonald, I Cody, Collins, James J

“…The first global metabolic models that incorporate reactive oxygen species in E. coli reveal targets for potentiating the action of antibacterials. The…”
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Antibiotics induce redox-related physiological alterations as part of their lethality by Dwyer, Daniel J, Belenky, Peter A, Yang, Jason H, MacDonald, I Cody, Martell, Jeffrey D, Takahashi, Noriko, Chan, Clement T Y, Lobritz, Michael A, Braff, Dana, Schwarz, Eric G, Ye, Jonathan D, Pati, Mekhala, Vercruysse, Maarten, Ralifo, Paul S, Allison, Kyle R, Khalil, Ahmad S, Ting, Alice Y, Walker, Graham C, Collins, James J

“…Deeper understanding of antibiotic-induced physiological responses is critical to identifying means for enhancing our current antibiotic arsenal. Bactericidal…”
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Interventions for treating oral leukoplakia to prevent oral cancer by Lodi, Giovanni, Franchini, Roberto, Warnakulasuriya, Saman, Varoni, Elena Maria, Sardella, Andrea, Kerr, Alexander R, Carrassi, Antonio, MacDonald, L C I, Worthington, Helen V

“…Oral leukoplakia is a relatively common oral lesion that, in a small proportion of people, precedes the development of oral cancer. Most leukoplakias are…”
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Tools and applications in synthetic biology by MacDonald, I. Cody, Deans, Tara L.

“…Advances in synthetic biology have enabled the engineering of cells with genetic circuits in order to program cells with new biological behavior, dynamic gene…”
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Solution-Processed Sintered Nanocrystal Solar Cells via Layer-by-Layer Assembly by Jasieniak, Jacek, MacDonald, Brandon I, Watkins, Scott E, Mulvaney, Paul

“…Solar cells made by high temperature and vacuum processes from inorganic semiconductors are at a perceived cost disadvantage when compared with…”
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Enhanced regulation of prokaryotic gene expression by a eukaryotic transcriptional activator by MacDonald, I. Cody, Seamons, Travis R., Emmons, Jonathan C., Javdan, Shwan B., Deans, Tara L.

“…Expanding the genetic toolbox for prokaryotic synthetic biology is a promising strategy for enhancing the dynamic range of gene expression and enabling new…”
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The importance of arterial systolic pressure (Push) in successful first pass aspiration technique for endovascular thrombectomy by Volders, D, Linehan, V, Macdonald, IR

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Orange juice consumption and its effect on blood lipid profile and indices of the metabolic syndrome; a randomised, controlled trial in an at-risk population by Simpson, E J, Mendis, B, Macdonald, I A

“…Data from epidemiological and in vitro studies suggest that orange juice (OJ) may have a positive impact on lipid metabolism. However, there have been reports…”
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The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism by Sebastián, Carlos, Zwaans, Bernadette M.M., Silberman, Dafne M., Gymrek, Melissa, Goren, Alon, Zhong, Lei, Ram, Oren, Truelove, Jessica, Guimaraes, Alexander R., Toiber, Debra, Cosentino, Claudia, Greenson, Joel K., MacDonald, Alasdair I., McGlynn, Liane, Maxwell, Fraser, Edwards, Joanne, Giacosa, Sofia, Guccione, Ernesto, Weissleder, Ralph, Bernstein, Bradley E., Regev, Aviv, Shiels, Paul G., Lombard, David B., Mostoslavsky, Raul

“…Reprogramming of cellular metabolism is a key event during tumorigenesis. Despite being known for decades (Warburg effect), the molecular mechanisms regulating…”
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Dietary carbohydrates: a review of international recommendations and the methods used to derive them by Buyken, A. E., Mela, D. J., Dussort, P., Johnson, I. T., Macdonald, I. A., Stowell, J. D., Brouns, F. J. P. H.

“…Background/objectives Renewed dietary recommendations for carbohydrates have recently been published by various international health authorities. The present…”
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Age-related changes in muscle architecture and metabolism in humans: The likely contribution of physical inactivity to age-related functional decline by Shur, N.F., Creedon, L., Skirrow, S., Atherton, P.J., MacDonald, I.A., Lund, J., Greenhaff, P.L.

“…•Ageing is associated with declines in muscle mass, quality and insulin sensitivity.•These features of ageing quickly manifest in young exposed to physical…”
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Nutritional science: Diet, lifestyle and health by Macdonald, I. A.

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Early score fluctuation and placebo response in a study of major depressive disorder by Targum, Steven D., Cameron, Beth R., Ferreira, Ludvina, MacDonald, I. David

“…Early score fluctuation in double-blind, placebo-controlled studies may affect the reliability of the baseline measurement and adversely affect the eventual…”
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Elevated surface chlorophyll associated with natural oil seeps in the Gulf of Mexico by D’souza, N. A., Subramaniam, A., Juhl, A. R., Hafez, M., Chekalyuk, A., Phan, S., Yan, B., MacDonald, I. R., Weber, S. C., Montoya, J. P.

“…Natural hydrocarbon seeps account for up to 47% of the oil released into the oceans. In situ and remote measurements of chlorophyll concentrations suggest that…”
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Virtual outcrop-based analysis of channel and crevasse splay sandstone body architecture in the Middle Jurassic Ravenscar Group, Yorkshire, NE England by Rahman, M. Mostafizur, Howell, J. A, Macdonald, D. I. M

“…Well-exposed fluvio-deltaic deposits of the Middle Jurassic Ravenscar Group (Yorkshire coast) provide a direct analogue for North Sea reservoirs, but previous…”
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N-terminal specific conjugation of extracellular matrix proteins to 2-pyridinecarboxaldehyde functionalized polyacrylamide hydrogels by Lee, Jessica P, Kassianidou, Elena, MacDonald, James I, Francis, Matthew B, Kumar, Sanjay

“…Abstract Polyacrylamide hydrogels have been used extensively to study cell responses to the mechanical and biochemical properties of extracellular matrix…”
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History and development of validation with the ESP-r simulation program by Strachan, P.A., Kokogiannakis, G., Macdonald, I.A.

“…It is well recognised that validation of dynamic building simulation programs is a long-term complex task. There have been many large national and…”
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Variability in Sr:Ca and Ba:Ca ratios in water and fish otoliths across an estuarine salinity gradient by Macdonald, Jed I., Crook, David A.

“…Retracing movements of euryhaline fishes using otolith chemistry analysis is a complex task, requiring detailed knowledge of the relationships between otolith…”
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Cardiac dysfunction during exacerbations of chronic obstructive pulmonary disease by MacDonald, Martin I, Dr, Shafuddin, Eskandarain, MBBS, King, Paul T, Phd, Chang, Catherina L, MD, Bardin, Philip G, Prof, Hancox, Robert J, MD

“…Summary Chronic obstructive pulmonary disease (COPD) and cardiovascular disease often coexist, and acute cardiac events frequently occur during COPD…”
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