Search Results - "MacDonald, Christopher"

Hippocampal “Time Cells” Bridge the Gap in Memory for Discontiguous Events by MacDonald, Christopher J., Lepage, Kyle Q., Eden, Uri T., Eichenbaum, Howard

“…The hippocampus is critical to remembering the flow of events in distinct experiences and, in doing so, bridges temporal gaps between discontiguous events…”
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Crucial role for CA2 inputs in the sequential organization of CA1 time cells supporting memory by MacDonald, Christopher J., Tonegawa, Susumu

“…There is considerable evidence for hippocampal time cells that briefly activate in succession to represent the temporal structure of memories. Previous studies…”
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Distinct hippocampal time cell sequences represent odor memories in immobilized rats by MacDonald, Christopher J, Carrow, Stephen, Place, Ryan, Eichenbaum, Howard

“…Previous studies have revealed the existence of hippocampal "time cells," principal neurons in CA1 that fire at specific moments in temporally organized…”
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Activating positive memory engrams suppresses depression-like behaviour by Ramirez, Steve, Liu, Xu, MacDonald, Christopher J., Moffa, Anthony, Zhou, Joanne, Redondo, Roger L., Tonegawa, Susumu

“…Acute re-activation of a positive memory engram suppresses depression-like behaviour in mice exposed to chronic stress, mediated by a…”
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Prospective and retrospective duration memory in the hippocampus: is time in the foreground or background? by MacDonald, Christopher J.

“…Psychologists have long distinguished between prospective and retrospective timing to highlight the difference between our sense of duration during an…”
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REPLY TO LEHR AND STÖBER: What’s in a name? On the distinction between temporal coding and internally driven activity by MacDonald, Christopher J., Tonegawa, Susumu

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The Characteristics and Geographic Origins of King Harold Godwineson's Army at the Battle of Hastings by Hewitt, Christopher Macdonald

“…The Battle of Hastings is without question one of the more important conflicts in English history, representing the last time England was successfully invaded…”
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Entorhinal-Hippocampal Neuronal Circuits Bridge Temporally Discontiguous Events by Kitamura, Takashi, Macdonald, Christopher J, Tonegawa, Susumu

“…The entorhinal cortex (EC)-hippocampal (HPC) network plays an essential role for episodic memory, which preserves spatial and temporal information about the…”
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A unified mathematical framework for coding time, space, and sequences in the hippocampal region by Howard, Marc W, MacDonald, Christopher J, Tiganj, Zoran, Shankar, Karthik H, Du, Qian, Hasselmo, Michael E, Eichenbaum, Howard

“…The medial temporal lobe (MTL) is believed to support episodic memory, vivid recollection of a specific event situated in a particular place at a particular…”
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Motivation and Barriers to Maintaining Lifestyle Changes in Patients with Type 2 Diabetes after an Intensive Lifestyle Intervention (The U-TURN Trial): A Longitudinal Qualitative Study by Schmidt, Sabrina K, Hemmestad, Liv, MacDonald, Christopher S, Langberg, Henning, Valentiner, Laura S

“…The purpose of this study was to explore and identify factors that influence motivation for and barriers to adopting and maintaining lifestyle changes in…”
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The historical topography of the Battle of Hastings: A geographical reconstruction by Hewitt, Christopher Macdonald

“…In 1066, English and Norman forces engaged in a decisive battle near Hastings. The battlefield itself provides an example of the way in which physical…”
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Efficient computation of the Grünwald–Letnikov fractional diffusion derivative using adaptive time step memory by MacDonald, Christopher L., Bhattacharya, Nirupama, Sprouse, Brian P., Silva, Gabriel A.

“…Computing numerical solutions to fractional differential equations can be computationally intensive due to the effect of non-local derivatives in which all…”
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Cytokine-induced MMP13 Expression in Human Chondrocytes Is Dependent on Activating Transcription Factor 3 (ATF3) Regulation by Chan, Chun Ming, Macdonald, Christopher D., Litherland, Gary J., Wilkinson, David J., Skelton, Andrew, Europe-Finner, G. Nicholas, Rowan, Andrew D.

“…Irreversible breakdown of cartilage extracellular matrix (ECM) by the collagenase matrix metalloproteinase 13 (MMP13) represents a key event in osteoarthritis…”
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A systematic review of adherence to physical activity interventions in individuals with type 2 diabetes by MacDonald, Christopher S., Ried‐Larsen, Mathias, Soleimani, Jalal, Alsawas, Mouaz, Lieberman, Daniel E., Ismail, Abdalla S., Serafim, Laura P., Yang, Ting, Prokop, Larry, Joyner, Michael, Murad, Mohammad Hassan, Barwise, Amelia

“…Lifestyle interventions are pivotal for successful management of type 2 diabetes (T2D), however, the proportion of people with T2D adhering to physical…”
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Cytokine-induced cysteine- serine-rich nuclear protein-1 (CSRNP1) selectively contributes to MMP1 expression in human chondrocytes by Macdonald, Christopher D, Falconer, Adrian M D, Chan, Chun Ming, Wilkinson, David J, Skelton, Andrew, Reynard, Louise, Litherland, Gary J, Europe-Finner, G Nicholas, Rowan, Andrew D

“…Irreversible cartilage collagen breakdown by the collagenolytic matrix metalloproteinases (MMPs)-1 and MMP-13 represents a key event in pathologies associated…”
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In vivo stimulus-induced vasodilation occurs without IP3 receptor activation and may precede astrocytic calcium increase by Nizar, Krystal, Uhlirova, Hana, Tian, Peifang, Saisan, Payam A, Cheng, Qun, Reznichenko, Lidia, Weldy, Kimberly L, Steed, Tyler C, Sridhar, Vishnu B, MacDonald, Christopher L, Cui, Jianxia, Gratiy, Sergey L, Sakadzić, Sava, Boas, David A, Beka, Thomas I, Einevoll, Gaute T, Chen, Ju, Masliah, Eliezer, Dale, Anders M, Silva, Gabriel A, Devor, Anna

“…Calcium-dependent release of vasoactive gliotransmitters is widely assumed to trigger vasodilation associated with rapid increases in neuronal activity…”
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The Impact of Cervical Musculoskeletal Disorders on UK Consultant Plastic Surgeons: Can We Reduce Morbidity With Applied Ergonomics? by Godwin, Yvette, Macdonald, Christopher R, Kaur, Sarbjit, Zhelin, Li, Baber, Christopher

“…Based on anecdotal and observational evidence, we hypothesized that the prevalence of cervical musculoskeletal disorder (C-MSD) would be high among plastic…”
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Type 2 diabetes remission 1 year after an intensive lifestyle intervention: A secondary analysis of a randomized clinical trial by Ried‐Larsen, Mathias, Johansen, Mette Y., MacDonald, Christopher S., Hansen, Katrine B., Christensen, Robin, Wedell‐Neergaard, Anne‐Sophie, Pilmark, Nanna Skytt, Langberg, Henning, Vaag, Allan A., Pedersen, Bente K., Karstoft, Kristian

“…Aim To investigate whether an intensive lifestyle intervention induces partial or complete type 2 diabetes (T2D) remission. Materials and methods In a…”
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Maximum Strength, Rate of Force Development, Jump Height, and Peak Power Alterations in Weightlifters across Five Months of Training by Hornsby, W Guy, Gentles, Jeremy A, MacDonald, Christopher J, Mizuguchi, Satoshi, Ramsey, Michael W, Stone, Michael H

“…The purpose of this monitoring study was to investigate how alterations in training affect changes in force-related characteristics and weightlifting…”
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Effects of an intensive lifestyle intervention on the underlying mechanisms of improved glycaemic control in individuals with type 2 diabetes: a secondary analysis of a randomised clinical trial by Johansen, Mette Y., Karstoft, Kristian, MacDonald, Christopher S., Hansen, Katrine B., Ellingsgaard, Helga, Hartmann, Bolette, Wewer Albrechtsen, Nicolai J., Vaag, Allan A., Holst, Jens J., Pedersen, Bente K., Ried-Larsen, Mathias

“…Aims/hypothesis The aim was to investigate whether an intensive lifestyle intervention, with high volumes of exercise, improves beta cell function and to…”
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