Search Results - "MacDermott, A. B"

Presynaptic ionotropic receptors and the control of transmitter release by MACDERMOTT, A. B, ROLE, L. W, SIEGELBAUM, S. A

“…The quantity of neurotransmitter released into the synaptic cleft, the reliability with which it is released, and the response of the postsynaptic cell to that…”
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Synaptic strengthening through activation of Ca2+-permeable AMPA receptors by GU, J. G, ALBUQUERQUE, C, LEE, C. J, MACDERMOTT, A. B

“…Postsynaptic Ca2+ elevation during synaptic transmission is an important trigger for short- and long-term changes in synaptic strength in the vertebrate…”
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Activation of ATP P2X receptors elicits glutamate release from sensory neuron synapses by Gu, Jianguo G, MacDermott, Amy B

“…Painful stimuli to the skin initiate action potentials in the peripheral terminals of dorsal root ganglion (DRG) neurons. These action potentials propagate to…”
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Presynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors modulate release of inhibitory amino acids in rat spinal cord dorsal horn by Engelman, H.S., Anderson, R.L., Daniele, C., MacDermott, A.B.

“…Local inhibition within the spinal cord dorsal horn is mediated by the neurotransmitters GABA and glycine and strongly influences nociceptive and temperature…”
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Mechanisms of GABA and glycine depolarization-induced calcium transients in rat dorsal horn neurons by Reichling, D B, Kyrozis, A, Wang, J, MacDermott, A B

“…1. The mechanisms and effects of GABA- and glycine-evoked depolarization were studied in cultured rat dorsal horn neurons using indo-1 recordings of [Ca2+]i…”
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Functional similarities and differences of AMPA and kainate receptors expressed by cultured rat sensory neurons by Lee, C.J., Labrakakis, C., Joseph, D.J., MacDermott, A.B.

“…Dorsal root ganglion neurons express functional AMPA and kainate receptors near their central terminals. Activation of these receptors causes a decrease in…”
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Adenosine triphosphate-evoked currents in cultured dorsal root ganglion neurons obtained from rat embryos: desensitization kinetics and modulation of glutamate release by Labrakakis, C, Gerstner, E, MacDermott, A.B

“…Sensory neurons express purinergic P2X receptors on their central and peripheral terminals as well as their cell bodies. ATP activation of these receptors…”
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Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor by Julius, David, MacDermott, Amy B., Axel, Richard, Jessell, Thomas M.

“…Neurons that release serotonin as a neurotransmitter project to most regions of the central and peripheral nervous system and mediate diverse neural functions…”
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Calcium entry through a subpopulation of AMPA receptors desensitized neighbouring NMDA receptors in rat dorsal horn neurons by Kyrozis, A, Goldstein, P A, Heath, M J, MacDermott, A B

“…1. A Ca(2+)-dependent interaction between non-NMDA and NMDA receptors was studied in embryonic rat dorsal horn neurons grown in tissue culture using…”
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Lanthanum actions on excitatory amino acid-gated currents and voltage-gated calcium currents in rat dorsal horn neurons by Reichling, D B, MacDermott, A B

“…1. The effects of lanthanum ions (La3+) on voltage-gated calcium currents (VGCCs) and excitatory amino acid (EAA)-evoked currents were characterized using…”
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Substance P elevates intracellular calcium in both neurons and glial cells from the dorsal horn of the spinal cord by Heath, M J, Womack, M D, MacDermott, A B

“…1. We used microfluorimetric measurement of [Ca2+]i to identify substance P-sensitive cells acutely isolated from the dorsal horn of neonatal rats. We then…”
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Activation of NMDA receptors drives action potentials in superficial dorsal horn from neonatal rats by Bardoni, Rita, Magherini, Pier Cosimo, MacDermott, Amy B

“…We have investigated the role of NMDA receptors in mediating synaptic transmission in spinal cord lamina II over the first 2 weeks of postnatal development…”
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Brief calcium transients evoked by glutamate receptor agonists in rat dorsal horn neurons: fast kinetics and mechanisms by Reichling, D B, MacDermott, A B

“…1. The calcium indicator dye, indo-1, was used to analyse the receptor-specific mechanisms of intracellular calcium ion ([Ca2+]i) responses evoked by…”
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L-proline activates glutamate and glycine receptors in cultured rat dorsal horn neurons by Henzi, V, Reichling, D B, Helm, S W, MacDermott, A B

“…The pharmacological actions of L-proline on excitatory and inhibitory amino acid receptors have been characterized under voltage-clamp conditions, using…”
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Sensory transmitters regulate intracellular calcium in dorsal horn neurons by Womack, M. D, MacDermott, A. B, Jessell, T. M

“…Primary afferent terminals in the dorsal horn of the spinal cord release excitatory amino acid and peptide transmitters that initiate the central processing of…”
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Activation of Kainate Receptors on Rat Sensory Neurons Evokes Action Potential Firing and May Modulate Transmitter Release by LEE, C. JUSTIN, ENGELMAN, H. S., MacCDERMOTT, A. B.

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Variable distributions of Ca(2+)-permeable and Ca(2+)-impermeable AMPA receptors on embryonic rat dorsal horn neurons by Goldstein, P A, Lee, C J, MacDermott, A B

“…1. By measuring the apparent reversal potential (aErev) of kainate- and alpha-amino-3-hydroxyl-5-methyl-4-isoxazole propionic acid (AMPA)-evoked currents…”
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Agonist- and voltage-gated calcium entry in cultured mouse spinal cord neurons under voltage clamp measured using arsenazo III by Mayer, ML, MacDermott, AB, Westbrook, GL, Smith, SJ, Barker, JL

“…Spinal cord neurons is dissociated cell culture were loaded with the calcium indicator arsenazo III using the whole-cell patch-clamp recording technique. Under…”
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The distribution of excitatory amino acid receptors on acutely dissociated dorsal horn neurons from postnatal rats by Arancio, O, Yoshimura, M, Murase, K, MacDermott, A B

“…Excitatory amino acid receptor distribution was mapped on acutely dissociated neurons from postnatal rat spinal cord dorsal horn. N-methyl D-aspartate,…”
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Differential distribution of excitatory amino acid receptors on embryonic rat spinal cord neurons in culture by Arancio, O, MacDermott, A B

“…1. Excitatory amino acid (EAA) receptors mediate synaptic transmission in many areas of the vertebrate CNS. To map the distribution of the EAA receptors, three…”
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