Search Results - "MacCulloch, Tara"

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  1. 1

    The influence of Holliday junction sequence and dynamics on DNA crystal self-assembly by Simmons, Chad R., MacCulloch, Tara, Krepl, Miroslav, Matthies, Michael, Buchberger, Alex, Crawford, Ilyssa, Šponer, Jiří, Šulc, Petr, Stephanopoulos, Nicholas, Yan, Hao

    Published in Nature communications (03-06-2022)
    “…The programmable synthesis of rationally engineered crystal architectures for the precise arrangement of molecular species is a foundational goal in…”
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    Journal Article
  2. 2

    Proximity-enhanced synthesis of DNA-peptide-DNA triblock molecules by MacCulloch, Tara, Novacek, Alexandra, Stephanopoulos, Nicholas

    “…We report a proximity-enhanced method to synthesize a peptide flanked by two different oligonucleotide handles. Our method relies on sequential bioorthogonal…”
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    Journal Article
  3. 3

    A Self‐Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High‐Resolution Structural Detail by Simmons, Chad R., MacCulloch, Tara, Zhang, Fei, Liu, Yan, Stephanopoulos, Nicholas, Yan, Hao

    Published in Angewandte Chemie International Edition (12-10-2020)
    “…DNA is an ideal molecule for the construction of 3D crystals with tunable properties owing to its high programmability based on canonical Watson–Crick base…”
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    Journal Article
  4. 4

    Tuning the Cavity Size and Chirality of Self-Assembling 3D DNA Crystals by Simmons, Chad R, Zhang, Fei, MacCulloch, Tara, Fahmi, Noureddine, Stephanopoulos, Nicholas, Liu, Yan, Seeman, Nadrian C, Yan, Hao

    Published in Journal of the American Chemical Society (16-08-2017)
    “…The foundational goal of structural DNA nanotechnologythe field that uses oligonucleotides as a molecular building block for the programmable self-assembly of…”
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    Journal Article
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    Rational Design of Self-Assembling Crystal Scaffolds and DNA-Peptide Hybrid Materials by MacCulloch, Tara

    Published 01-01-2021
    “…Since the conception of DNA nanotechnology, the field has evolved towards the development of complex, dynamic 3D structures. The predictability of Watson-Crick…”
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    Dissertation
  7. 7

    Site-Specific Arrangement and Structure Determination of Minor Groove Binding Molecules in Self-Assembled Three-Dimensional DNA Crystals by Simmons, Chad R, Buchberger, Alex, Henry, Skylar J W, Novacek, Alexandra, Fahmi, Nour Eddine, MacCulloch, Tara, Stephanopoulos, Nicholas, Yan, Hao

    Published in Journal of the American Chemical Society (06-12-2023)
    “…The structural analysis of guest molecules in rationally designed and self-assembling DNA crystals has proven an elusive goal since its conception…”
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    Journal Article
  8. 8

    Protein Corona Inhibits Endosomal Escape of Functionalized DNA Nanostructures in Living Cells by Smolková, Barbora, MacCulloch, Tara, Rockwood, Tyler F, Liu, Minghui, Henry, Skylar J. W, Frtús, Adam, Uzhytchak, Mariia, Lunova, Mariia, Hof, Martin, Jurkiewicz, Piotr, Dejneka, Alexandr, Stephanopoulos, Nicholas, Lunov, Oleg

    Published in ACS applied materials & interfaces (06-10-2021)
    “…DNA nanostructures (DNs) can be designed in a controlled and programmable manner, and these structures are increasingly used in a variety of biomedical…”
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    Journal Article
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  11. 11

    A Self‐Assembled Rhombohedral DNA Crystal Scaffold with Tunable Cavity Sizes and High‐Resolution Structural Detail by Simmons, Chad R., MacCulloch, Tara, Zhang, Fei, Liu, Yan, Stephanopoulos, Nicholas, Yan, Hao

    Published in Angewandte Chemie (12-10-2020)
    “…DNA is an ideal molecule for the construction of 3D crystals with tunable properties owing to its high programmability based on canonical Watson–Crick base…”
    Get full text
    Journal Article
  12. 12

    Uncovering temporospatial sensitive TBI targeting strategies via in vivo phage display by Martinez, Briana I, Mousa, Gergey Alzaem, Fleck, Kiera, MacCulloch, Tara, Diehnelt, Chris W, Stephanopoulos, Nicholas, Stabenfeldt, Sarah E

    Published in Science advances (22-07-2022)
    “…The heterogeneous pathophysiology of traumatic brain injury (TBI) is a barrier to advancing diagnostics and therapeutics, including targeted drug delivery. We…”
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    Journal Article