Search Results - "MacArthur, Grant A"

Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing by Wong, Stephen Q, Li, Jason, Tan, Angela Y-C, Vedururu, Ravikiran, Pang, Jia-Min B, Do, Hongdo, Ellul, Jason, Doig, Ken, Bell, Anthony, MacArthur, Grant A, Fox, Stephen B, Thomas, David M, Fellowes, Andrew, Parisot, John P, Dobrovic, Alexander

“…Clinical specimens undergoing diagnostic molecular pathology testing are fixed in formalin due to the necessity for detailed morphological assessment. However,…”
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No evidence that CDKN1B (p27) polymorphisms modify breast cancer risk in BRCA1 and BRCA2 mutation carriers by Spurdle, Amanda B., Deans, Andrew J., Duffy, David, Goldgar, David E., Chen, Xiaoqing, Beesley, Jonathan, Easton, Douglas F., Antoniou, Antonis C., Peock, Susan, Cook, Margaret, Nathanson, Katherine L., Domchek, Susan M., MacArthur, Grant A., Chenevix-Trench, Georgia

“…The p27 kip1 protein functions as an inhibitor of cyclin dependent kinase-2, and shows loss of expression in a large percentage of BRCA1 and BRCA2 breast…”
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