Search Results - "Macías‐Kauffer, Luis"

The Genetic Architecture of Diet‐Induced Hepatic Fibrosis in Mice by Hui, Simon T., Kurt, Zeyneb, Tuominen, Iina, Norheim, Frode, C.Davis, Richard, Pan, Calvin, Dirks, Darwin L., Magyar, Clara E., French, Samuel W., Chella Krishnan, Karthickeyan, Sabir, Simon, Campos‐Pérez, Francisco, Méndez‐Sánchez, Nahum, Macías‐Kauffer, Luis, León‐Mimila, Paola, Canizales‐Quinteros, Samuel, Yang, Xia, Beaven, Simon W., Huertas‐Vazquez, Adriana, Lusis, Aldons J.

“…We report the genetic analysis of a “humanized” hyperlipidemic mouse model for progressive nonalcoholic steatohepatitis (NASH) and fibrosis. Mice carrying…”
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Association of FTO, ABCA1, ADRB3, and PPARG variants with obesity, type 2 diabetes, and metabolic syndrome in a Northwest Mexican adult population by Velazquez-Roman, Jorge, Angulo-Zamudio, Uriel A., León-Sicairos, Nidia, Medina-Serrano, Julio, DeLira-Bustillos, Nora, Villamil-Ramírez, Hugo, Canizales-Quinteros, Samuel, Macías-Kauffer, Luis, Campos-Romero, Abraham, Alcántar-Fernández, Jonathan, Canizalez-Roman, Adrian

“…To identify associations among allelic variants of the genes FTO, ABCA1, ADRB3, and PPARG with anthropometric and biochemical traits, metabolic diseases…”
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Genome-Wide Association Study Identifies a Functional SIDT2 Variant Associated With HDL-C (High-Density Lipoprotein Cholesterol) Levels and Premature Coronary Artery Disease by León-Mimila, Paola, Villamil-Ramírez, Hugo, Macías-Kauffer, Luis R., Jacobo-Albavera, Leonor, López-Contreras, Blanca E., Posadas-Sánchez, Rosalinda, Posadas-Romero, Carlos, Romero-Hidalgo, Sandra, Morán-Ramos, Sofía, Domínguez-Pérez, Mayra, Olivares-Arevalo, Marisol, López-Montoya, Priscilla, Nieto-Guerra, Roberto, Acuña-Alonzo, Víctor, Macín-Pérez, Gastón, Barquera-Lozano, Rodrigo, Del-Río-Navarro, Blanca E., González-González, Israel, Campos-Pérez, Francisco, Gómez-Pérez, Francisco, Valdés, Victor J., Sampieri, Alicia, Reyes-García, Juan G., Carrasco-Portugal, Miriam del C., Flores-Murrieta, Francisco J., Aguilar-Salinas, Carlos A., Vargas-Alarcón, Gilberto, Shih, Diana, Meikle, Peter J., Calkin, Anna C., Drew, Brian G., Vaca, Luis, Lusis, Aldons J., Huertas-Vazquez, Adriana, Villarreal-Molina, Teresa, Canizales-Quinteros, Samuel

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Genetic variants in COL13A1, ADIPOQ and SAMM50, in addition to the PNPLA3 gene, confer susceptibility to elevated transaminase levels in an admixed Mexican population by Larrieta-Carrasco, Elena, Flores, Yvonne N., Macías-Kauffer, Luis R., Ramírez-Palacios, Paula, Quiterio, Manuel, Ramírez-Salazar, Eric G., León-Mimila, Paola, Rivera-Paredez, Berenice, Cabrera-Álvarez, Guillermo, Canizales-Quinteros, Samuel, Zhang, Zuo-Feng, López-Pérez, Tania V., Salmerón, Jorge, Velázquez-Cruz, Rafael

“…Non-alcoholic fatty liver disease (NAFLD) is the accumulation of extra fat in liver cells not caused by alcohol. Elevated transaminase levels are common…”
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Impact of COMT, PRODH and DISC1 Genetic Variants on Cognitive Performance of Patients with Schizophrenia by Fricke-Galindo, Ingrid, Pérez-Aldana, Blanca E., Macías-Kauffer, Luis R., González-Arredondo, Susana, Dávila-Ortiz de Montellano, David, Aviña-Cervantes, Carlos L., López-López, Marisol, Rodríguez-Agudelo, Yaneth, Monroy-Jaramillo, Nancy

“…Cognitive impairment in schizophrenia (SCZ) is a core feature, relevant for the disease prognosis and functional capacity of the patients. It has also been…”
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Selection scan in Native Americans of Mexico identifies FADS2 rs174616: Evidence of gene-diet interactions affecting lipid levels and Delta-6-desaturase activity by Romero-Hidalgo, Sandra, Sagaceta-Mejía, Janine, Villalobos-Comparán, Marisela, Tejero, María Elizabeth, Domínguez-Pérez, Mayra, Jacobo-Albavera, Leonor, Posadas-Sánchez, Rosalinda, Vargas-Alarcón, Gilberto, Posadas-Romero, Carlos, Macías-Kauffer, Luis, Vadillo-Ortega, Felipe, Contreras-Sieck, Miguel Angel, Acuña-Alonzo, Víctor, Barquera, Rodrigo, Macín, Gastón, Binia, Aristea, Guevara-Chávez, Jose Guadalupe, Sebastián-Medina, Leticia, Menjívar, Martha, Canizales-Quinteros, Samuel, Carnevale, Alessandra, Villarreal-Molina, Teresa

“…Searching for positive selection signals across genomes has identified functional genetic variants responding to environmental change. In Native Americans of…”
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An Amino Acid Signature Associated with Obesity Predicts 2-Year Risk of Hypertriglyceridemia in School-Age Children by Moran-Ramos, Sofia, Ocampo-Medina, Elvira, Gutierrez-Aguilar, Ruth, Macías-Kauffer, Luis, Villamil-Ramírez, Hugo, López-Contreras, Blanca E., León-Mimila, Paola, Vega-Badillo, Joel, Gutierrez-Vidal, Roxana, Villarruel-Vazquez, Ricardo, Serrano-Carbajal, Erandi, Del-Río-Navarro, Blanca E, Huertas-Vázquez, Adriana, Villarreal-Molina, Teresa, Ibarra-Gonzalez, Isabel, Vela-Amieva, Marcela, Aguilar-Salinas, Carlos A., Canizales-Quinteros, Samuel

“…Childhood obesity is associated with a number of metabolic abnormalities leading to increased cardiovascular risk. Metabolites can be useful as early…”
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Low Salivary Amylase Gene ( AMY1 ) Copy Number Is Associated with Obesity and Gut Prevotella Abundance in Mexican Children and Adults by León-Mimila, Paola, Villamil-Ramírez, Hugo, López-Contreras, Blanca E, Morán-Ramos, Sofía, Macias-Kauffer, Luis R, Acuña-Alonzo, Víctor, Del Río-Navarro, Blanca E, Salmerón, Jorge, Velazquez-Cruz, Rafael, Villarreal-Molina, Teresa, Aguilar-Salinas, Carlos A, Canizales-Quinteros, Samuel

“…Genome-wide association studies (GWAS) have identified copy number variants (CNVs) associated with obesity in chromosomal regions 1p31.1, 10q11.22, 11q11,…”
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Association of PCSK1 and PPARG1 Allelic Variants with Obesity and Metabolic Syndrome in Mexican Adults by Velazquez-Roman, Jorge, Angulo-Zamudio, Uriel A., Leon-Sicairos, Nidia, Flores-Villaseñor, Hector, Benitez-Baez, Miriam, Espinoza-Salomón, Ana, Karam-León, Alejandra, Villamil-Ramírez, Hugo, Canizales-Quinteros, Samuel, Macías-Kauffer, Luis, Monroy-Higuera, Jose, Acosta-Smith, Erika, Canizalez-Roman, Adrian

“…Metabolic diseases, including obesity, diabetes, and metabolic syndrome, are among the most important public health challenges worldwide. Metabolic diseases…”
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Influence of Genetic and Non-Genetic Risk Factors for Serum Uric Acid Levels and Hyperuricemia in Mexicans by Rivera-Paredez, Berenice, Macías-Kauffer, Luis, Fernandez-Lopez, Juan Carlos, Villalobos-Comparán, Marisela, Martinez-Aguilar, Mayeli M, de la Cruz-Montoya, Aldo, Ramírez-Salazar, Eric G, Villamil-Ramírez, Hugo, Quiterio, Manuel, Ramírez-Palacios, Paula, Romero-Hidalgo, Sandra, Villarreal-Molina, María Teresa, Denova-Gutiérrez, Edgar, Flores, Yvonne N, Canizales-Quinteros, Samuel, Salmerón, Jorge, Velázquez-Cruz, Rafael

“…Risk of hyperuricemia is modified by genetic and environmental factors. Our aim was to identify factors associated with serum uric acid levels and…”
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Genetic contributors to serum uric acid levels in Mexicans and their effect on premature coronary artery disease by Macias-Kauffer, Luis R., Villamil-Ramírez, Hugo, León-Mimila, Paola, Jacobo-Albavera, Leonor, Posadas-Romero, Carlos, Posadas-Sánchez, Rosalinda, López-Contreras, Blanca E., Morán-Ramos, Sofía, Romero-Hidalgo, Sandra, Acuña-Alonzo, Víctor, del-Río-Navarro, Blanca E., Bortolini, Maria-Cátira, Gallo, Carla, Bedoya, Gabriel, Rothhammer, Francisco, González-Jose, Rolando, Ruiz-Linares, Andrés, Stephens, Christopher R., Velazquez-Cruz, Rafael, Fernández del Valle-Laisequilla, Cecilia, Reyes-García, Juan G., Barranco Garduño, Lina M., Carrasco-Portugal, Miriam del C., Flores-Murrieta, Francisco J., Vargas-Alarcón, Gilberto, Aguilar-Salinas, Carlos A., Villarreal-Molina, Teresa, Canizales-Quinteros, Samuel

“…Serum uric acid (SUA) is a heritable trait associated with cardiovascular risk factors and coronary artery disease (CAD). Genome wide association studies…”
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Native American ancestry significantly contributes to neuromyelitis optica susceptibility in the admixed Mexican population by Romero-Hidalgo, Sandra, Flores-Rivera, José, Rivas-Alonso, Verónica, Barquera, Rodrigo, Villarreal-Molina, María Teresa, Antuna-Puente, Bárbara, Macias-Kauffer, Luis Rodrigo, Villalobos-Comparán, Marisela, Ortiz-Maldonado, Jair, Yu, Neng, Lebedeva, Tatiana V., Alosco, Sharon M., García-Rodríguez, Juan Daniel, González-Torres, Carolina, Rosas-Madrigal, Sandra, Ordoñez, Graciela, Guerrero-Camacho, Jorge Luis, Treviño-Frenk, Irene, Escamilla-Tilch, Monica, García-Lechuga, Maricela, Tovar-Méndez, Víctor Hugo, Pacheco-Ubaldo, Hanna, Acuña-Alonzo, Victor, Bortolini, Maria-Cátira, Gallo, Carla, Bedoya, Gabriel, Rothhammer, Francisco, González-Jose, Rolando, Ruiz-Linares, Andrés, Canizales-Quinteros, Samuel, Yunis, Edmond, Granados, Julio, Corona, Teresa

“…Neuromyelitis Optica (NMO) is an autoimmune disease with a higher prevalence in non-European populations. Because the Mexican population resulted from the…”
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EXPLORATORY ANALYSIS OF POLYGENIC RISK SCORES FOR PSYCHIATRIC DISORDERS: APPLIED TO DUAL DIAGNOSIS by Martínez-Magaña, José J, Gonzalez-Castro, Thelma B, Genís-Mendoza, Alma D, Tovilla-Zárate, Carlos A, Juárez-Rojop, Isela E, Saucedo-Uribe, Erasmo, Rodríguez-Mayoral, Oscar, Lanzagorta, Nuria, Escamilla, Michael, Macías-Kauffer, Luis, Nicolini, Humberto

“…Concurrence of substance use disorders (SUDs) is high in individuals with psychiatric illnesses; more importantly, individuals with both disorders (dual…”
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Effect of Gut Microbial Enterotypes on the Association between Habitual Dietary Fiber Intake and Insulin Resistance Markers in Mexican Children and Adults by Martinez-Medina, Jennifer N., Flores-Lopez, Regina, López-Contreras, Blanca E., Villamil-Ramirez, Hugo, Guzman-Muñoz, Daniela, Macias-Kauffer, Luis R., León-Mimila, Paola, Granados-Portillo, Omar, Del-Rio-Navarro, Blanca E., Gómez-Perez, Francisco J., Aguilar-Salinas, Carlos A., Torres, Nimbe, Tovar, Armando R., Canizales-Quinteros, Samuel, Moran-Ramos, Sofia

“…Dietary fiber (DF) is a major substrate for the gut microbiota that contributes to metabolic health. Recent studies have shown that diet–metabolic phenotype…”
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A combined linkage and association strategy identifies a variant near the GSTP1 gene associated with BMI in the Mexican population by Villamil-Ramírez, Hugo, León-Mimila, Paola, Macias-Kauffer, Luis R, Canizalez-Román, Adrián, Villalobos-Comparán, Marisela, León-Sicairos, Nidia, Vega-Badillo, Joel, Sánchez-Muñoz, Fausto, López-Contreras, Blanca, Morán-Ramos, Sofía, Villarreal-Molina, Teresa, Zurita, Luis C, Campos-Pérez, Francisco, Huertas-Vazquez, Adriana, Bojalil, Rafael, Romero-Hidalgo, Sandra, Aguilar-Salinas, Carlos A, Canizales-Quinteros, Samuel

“…Obesity is a major public health concern in Mexico and worldwide. Although the estimated heritability is high, common variants identified by genome-wide…”
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A genetic risk score is associated with hepatic triglyceride content and non-alcoholic steatohepatitis in Mexicans with morbid obesity by León-Mimila, Paola, Vega-Badillo, Joel, Gutiérrez-Vidal, Roxana, Villamil-Ramírez, Hugo, Villareal-Molina, Teresa, Larrieta-Carrasco, Elena, López-Contreras, Blanca E., Kauffer, Luis R. Macías, Maldonado-Pintado, Diana G., Méndez-Sánchez, Nahúm, Tovar, Armando R., Hernández-Pando, Rogelio, Velázquez-Cruz, Rafael, Campos-Pérez, Francisco, Aguilar-Salinas, Carlos A., Canizales-Quinteros, Samuel

“…Genome-wide association studies have identified single nucleotide polymorphisms (SNPs) near/in PNPLA3, NCAN, LYPLAL1, PPP1R3B, and GCKR genes associated with…”
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A higher bacterial inward BCAA transport driven by Faecalibacterium prausnitzii is associated with lower serum levels of BCAA in early adolescents by Moran-Ramos, Sofia, Macias-Kauffer, Luis, López-Contreras, Blanca E, Villamil-Ramírez, Hugo, Ocampo-Medina, Elvira, León-Mimila, Paola, Del Rio-Navarro, Blanca E, Granados-Portillo, Omar, Ibarra-Gonzalez, Isabel, Vela-Amieva, Marcela, Tovar, Armando R, Torres, Nimbe, Gomez-Perez, Francisco J, Aguilar-Salinas, Carlos, Canizales-Quinteros, Samuel

“…Elevations of circulating branched-chain amino acids (BCAA) are observed in humans with obesity and metabolic comorbidities, such as insulin resistance…”
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A Multi-Omic Analysis for Low Bone Mineral Density in Postmenopausal Women Suggests a Relationship between Diet, Metabolites, and Microbiota by Palacios-González, Berenice, Ramírez-Salazar, Eric G., Rivera-Paredez, Berenice, Quiterio, Manuel, Flores, Yvonne N., Macias-Kauffer, Luis, Moran-Ramos, Sofía, Denova-Gutiérrez, Edgar, Ibarra-González, Isabel, Vela-Amieva, Marcela, Canizales-Quinteros, Samuel, Salmerón, Jorge, Velázquez-Cruz, Rafael

“…The effect of microbiota composition and its health on bone tissue is a novel field for research. However, their associations with bone mineral density (BMD)…”
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Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) in two Mexican brothers harboring a novel mutation in the ECGF1 gene by Monroy, Nancy, Macías Kauffer, Luis R, Mutchinick, Osvaldo M

“…Abstract Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a rare autosomal recessive disease caused by mutations in the thymidine phosphorylase…”
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Effect of the Melanocortin 4-Receptor Ile269Asn Mutation on Weight Loss Response to Dietary, Phentermine and Bariatric Surgery Interventions by Salazar-Valencia, Itzel G, Villamil-Ramírez, Hugo, Barajas-Olmos, Francisco, Guevara-Cruz, Martha, Macias-Kauffer, Luis R, García-Ortiz, Humberto, Hernández-Vergara, Omar, Díaz de Sandy-Galán, David Alberto, León-Mimila, Paola, Centeno-Cruz, Federico, González-Salazar, Luis E, Guizar-Heredia, Rocío, Pichardo-Ontiveros, Edgar, Jacobo-Albavera, Leonor, Posadas-Sánchez, Rosalinda, Vargas-Alarcón, Gilberto, Velazquez-Cruz, Rafael, Gutiérrez-Aguilar, Ruth, Zerrweck, Carlos, Rocha-González, Héctor Isaac, Reyes-García, Juan Gerardo, Carrasco-Portugal, Miriam Del C, Flores-Murrieta, Francisco Javier, Tovar, Armando R, Orozco, Lorena, Villarreal-Molina, Teresa, Canizales-Quinteros, Samuel

“…The loss of function melanocortin 4-receptor ( ) Ile269Asn mutation has been proposed as one of the most important genetic contributors to obesity in the…”
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