Isolation and Characterization of Madariaga Virus from a Horse in Paraíba State, Brazil

Summary Madariaga virus (MADV), the new species designation for the South American isolates of eastern equine encephalitis virus (EEEV), is genetically divergent and substantially different in ecology and pathogenesis from North American EEEV strains. We isolated and characterized a MADV isolate obt...

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Bibliographic Details
Published in:	Transboundary and emerging diseases Vol. 64; no. 3; pp. 990 - 993
Main Authors:	Silva, M. L. C. R., Auguste, A. J., Terzian, A. C. B., Vedovello, D., Riet‐Correa, F., Macário, V. M. K., Mourão, M. P. G., Ullmann, L. S., Araújo, J. P., Weaver, S. C., Nogueira, M. L.
Format:	Journal Article
Language:	English
Published:	Germany Hindawi Limited 01-06-2017
Subjects:	Aedes - cytology Aedes - virology Alphavirus Animals arboviruses Brain - virology Brazil Cells, Cultured eastern equine encephalitis virus Encephalitis Virus, Eastern Equine - classification Encephalitis Virus, Eastern Equine - genetics Encephalitis Virus, Eastern Equine - isolation & purification Encephalomyelitis, Equine - veterinary Encephalomyelitis, Equine - virology horse Horse Diseases - virology Horses Madariaga virus Mice Phylogeny Reoviridae horse Alphavirus eastern equine encephalitis virus Madariaga virus arboviruses
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Summary:	Summary Madariaga virus (MADV), the new species designation for the South American isolates of eastern equine encephalitis virus (EEEV), is genetically divergent and substantially different in ecology and pathogenesis from North American EEEV strains. We isolated and characterized a MADV isolate obtained from a horse in Brazil. Our results support previous phylogenetic studies showing there are three genetically distinct MADV lineages. The MADV isolate from Paraíba State belongs to the South American lineage III and is closely related to Peruvian, Colombian and Venezuelan isolates.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3 ObjectType-Article-1 ObjectType-Feature-2 Ana C. B. Terzian - anacarolinaterzian@gmail.com Albert J. Auguste - aj1augus@utmb.edu João P. Araújo Jr - jpessoa@ibb.unesp.br Scott C. Weaver - sweaver@utmb.edu Valeria M. K. Macário – muni_kramer@hotmail.com Maria P.G. Mourão - mariapaula.mourao@gmail.com Leila Sabrina Ullmann - leila_ullmann@yahoo.com.br Maria Luana C. R. Silva - luacristiny@yahoo.com.br Danila Vedovello – danvedo@hotmail.com Franklin Riet-Correa - franklin.riet@pq.cnpq.br
ISSN:	1865-1674 1865-1682
DOI:	10.1111/tbed.12441