Search Results - "Maayani, S"

Characterization of the 5-hydroxytryptamine1a receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig and rat hippocampal membranes by De Vivo, M, Maayani, S

“…The inhibition of forskolin-stimulated adenylate cyclase activity by 5-hydroxytryptamine (5-HT) receptor agonists was measured in guinea pig and rat…”
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Lack of 5-hydroxytryptamine1A-mediated inhibition of adenylyl cyclase in dorsal raphe of male and female rats by Clarke, W P, Yocca, F D, Maayani, S

“…In the rat hippocampus, 5-hydroxytryptamine (5-HT)1A receptors couple to two independent effector mechanisms, the inhibition of adenylyl cyclase activity and…”
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Signal transduction differences between 5-hydroxytryptamine type 2A and type 2C receptor systems by Berg, K A, Clarke, W P, Sailstad, C, Saltzman, A, Maayani, S

“…The cDNAs for human 5-hydroxytryptamine (5-HT)2C and 5-HT2A receptors were stably transfected separately into parent Chinese hamster ovary cells, and cell…”
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Pharmacological studies of human erectile tissue: characteristics of spontaneous contractions and alterations in α‐adrenoceptor responsiveness with age and disease in isolated tissues by Christ, George J., Maayani, Saul, Valcic, Mira, Melman, Arnold

“…1 The pathophysiology of impotence related to vascular smooth muscle dysfunction in the male corpus cavernosum was studied on human isolated erectile tissue…”
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Activation of Gi-coupled receptors releases a tonic state of inhibited platelet aggregation by Maayani, S, Schwarz, T, Martinez, R, Tagliente, T M

“…Single-receptor pharmacology does not satisfactorily explain the physiology of the ADP-induced platelet aggregation response. It has been shown that, in…”
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Interactions between Effectors Linked to Serotonin Receptors by BERG, K. A., MAAYANI, S., CLARKE, W. P.

“…In general, there are two types of interactions between effector signaling pathways. “Homologous” interactions are those that occur within a receptor system to…”
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Pharmacological characterization of two 5-hydroxytryptamine receptors coupled to adenylate cyclase in guinea pig hippocampal membranes by Shenker, A, Maayani, S, Weinstein, H, Green, J P

“…Two 5-hydroxytryptamine (5-HT) receptors mediate stimulation of adenylate cyclase activity in membranes of adult guinea pig hippocampus. The two receptors were…”
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5-Hydroxytryptamine type 2A receptors regulate cyclic AMP accumulation in a neuronal cell line by protein kinase C-dependent and calcium/calmodulin-dependent mechanisms by Berg, K A, Clarke, W P, Chen, Y, Ebersole, B J, McKay, R D, Maayani, S

“…The effects of 5-hydroxytryptamine (5-HT)2A receptor activation on cAMP formation were studied in a cell line derived from embryonic rat cortex (A1A1). 5-HT…”
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Respiratory Function in Poultry Workers and Pharmacologic Characterization of Poultry Dust Extract by Zuskin, E., Mustajbegovic, J., Schachter, E.N., Kern, J., Rienzi, N., Goswami, S., Marom, Z., Maayani, S.

“…A group of 343 workers (252 males and 91 females) employed in four poultry farms in Croatia was studied for the prevalence of acute and chronic respiratory…”
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Pleiotropic Behavior of 5-HT2A and 5-HT2C Receptor Agonists by BERG, K. A., CLARKE, W. P., MAAYANI, S., GOLDFARB, J.

“…There is now considerable evidence that a single receptor subtype can couple to multiple effector pathways within a cell. Recently, Kenakin proposed a new…”
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The balance of concurrent aggregation and deaggregation processes in platelets is linked to differential occupancy of ADP receptor subtypes by Maayani, Thomas M. Tagliente, Todd Schwarz, Giorgio Martinelli, Rafael Martinez, Linda Shore-Lesserson, Saul

“…Deaggregation, the partial reversal of the initial aggregation of platelets is observed following low, but not higher, micromolar ADP concentrations. This…”
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5-hydroxytryptamine2C receptor activation inhibits 5-hydroxytryptamine1B-like receptor function via arachidonic acid metabolism by Berg, K A, Maayani, S, Clarke, W P

“…We previously reported that in Chinese hamster ovary (CHO) cells, 5-hydroxytryptamine (5-HT)1B-like (CHO/5-HT1B) receptor-mediated inhibition of…”
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Deaggregation is an integral component of the response of platelets to ADP in vitro : kinetic studies of literature and original data by Maayani, Saul, Tagliente, Thomas M., Schwarz, Todd, Craddock-Royal, Barbara, Alcala, Carlos, Marrero, Gabriel, Martinez, Rafael

“…Adenosine diphosphate (ADP) is recognized as an important mediator of platelet aggregation. Transient aggregation at low ( h 1 w M), and sustained aggregation…”
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Tricyclic antidepressant drugs block histamine H2 receptor in brain by Green, J P, Maayani, S

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Pertussis toxin-sensitive guanine nucleotide-binding protein(S) couple adenosine A1 and 5-hydroxytryptamine1A receptors to the same effector systems in rat hippocampus: biochemical and electrophysiological studies by Zgombick, J M, Beck, S G, Mahle, C D, Craddock-Royal, B, Maayani, S

“…Distinct membrane receptors that elicit similar cellular responses may share elements of signal transduction. In the present study, rat hippocampal adenosine…”
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Receptor-mediated mutual-effect amplification elicited by phenylephrine and serotonin in isolated rabbit aorta by Christ, G J, Goldfarb, J, Maayani, S

“…Phenylephrine (PE) and 5-hydroxytryptamine (5-HT) were utilized to study the effects of simultaneous coactivation of the alpha-1 and 5-HT2 receptors,…”
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5-Hydroxytryptamine receptor in isolated rabbit aorta: characterization with tryptamine analogs by Clancy, B M, Maayani, S

“…The 5-HT2 receptor in isolated rabbit thoracic aorta was characterized by examining the relationships between structure and activity of nine tryptamine…”
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Interactions between responses mediated by activation of adenosine A2 receptors and alpha 1-adrenoceptors in the rabbit isolated aorta by Wiener, H L, Thalody, G P, Maayani, S

“…1. This paper describes aspects of the functional antagonism between the responses mediated by activated alpha 1-adrenoceptors and adenosine A2 receptors in…”
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Kinetic characterization of 5-hydroxytryptamine receptor desensitization in isolated guinea-pig trachea and rabbit aorta by Ben-Harari, R R, Dalton, B A, Osman, R, Maayani, S

“…Desensitization of the contractile response mediated by the 5-hydroxytryptamine2 (5-HT2) receptor in the isolated guinea-pig trachea and rabbit aorta is a…”
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Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus by Berg, K A, Maayani, S, Goldfarb, J, Scaramellini, C, Leff, P, Clarke, W P

“…There are many examples of a single receptor coupling directly to more than one cellular signal transduction pathway. Although traditional receptor theory…”
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