Search Results - "Maassen, J"

Raman spectroscopy of the internal strain of a graphene layer grown on copper tuned by chemical vapor deposition by Yu, V., Whiteway, E., Maassen, J., Hilke, M.

Get full text

Cardiac dysfunction induced by high-fat diet is associated with altered myocardial insulin signalling in rats by OUWENS, D. M, BOER, C, FODOR, M, DE GALAN, P, HEINE, R. J, MAASSEN, J. A, DIAMANT, M

“…Diabetic cardiomyopathy (DCM) is common in type 2 diabetes. In DCM, insulin resistance may alter cardiac substrate supply and utilisation leading to changes in…”
Get full text

Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps by Groenewoud, M. J, Dekker, J. M, Fritsche, A, Reiling, E, Nijpels, G, Heine, R. J, Maassen, J. A, Machicao, F, Schäfer, S. A, Häring, H. U, t Hart, L. M, van Haeften, T. W

“…Aims/hypothesis Genome-wide association studies have recently identified novel type 2 diabetes susceptibility gene regions. We assessed the effects of six of…”
Get full text

Application of ion exchange and extraction chromatography to the separation of actinium from proton-irradiated thorium metal for analytical purposes by Radchenko, V., Engle, J.W., Wilson, J.J., Maassen, J.R., Nortier, F.M., Taylor, W.A., Birnbaum, E.R., Hudston, L.A., John, K.D., Fassbender, M.E.

“…•Actinium-225 (t1/2=9.92d) is an α-emitting radionuclide for use in targeted alpha therapy.•During proton irradiation of thorium metal, long-lived 227Ac…”
Get full text

Fluorescence efficiency and visible re-emission spectrum of tetraphenyl butadiene films at extreme ultraviolet wavelengths by Gehman, V.M., Seibert, S.R., Rielage, K., Hime, A., Sun, Y., Mei, D.-M., Maassen, J., Moore, D.

“…A large number of current and future experiments in neutrino and dark matter detection use the scintillation light from noble elements as a mechanism for…”
Get full text

Combined effects of single-nucleotide polymorphisms in GCK, GCKR, G6PC2 and MTNR1B on fasting plasma glucose and type 2 diabetes risk by Reiling, E, van 't Riet, E, Groenewoud, M. J, Welschen, L. M. C, van Hove, E. C, Nijpels, G, Maassen, J. A, Dekker, J. M, t Hart, L. M

“…Aims/hypothesis Variation in fasting plasma glucose (FPG) within the normal range is a known risk factor for the development of type 2 diabetes. Several…”
Get full text

Fatty acid-induced mitochondrial uncoupling in adipocytes as a key protective factor against insulin resistance and beta cell dysfunction: a new concept in the pathogenesis of obesity-associated type 2 diabetes mellitus by Maassen, J. A, Romijn, J. A, Heine, R. J

“…Type 2 diabetes is associated with excessive food intake and a sedentary lifestyle. Local inflammation of white adipose tissue induces cytokine-mediated…”
Get full text

Mitochondrial diabetes: molecular mechanisms and clinical presentation by Maassen, J Antonie, 'T Hart, Leen M, Van Essen, Einar, Heine, Rob J, Nijpels, Giel, Jahangir Tafrechi, Roshan S, Raap, Anton K, Janssen, George M C, Lemkes, Herman H P J

“…Mutations in mitochondrial DNA (mtDNA) associate with various disease states. A few mtDNA mutations strongly associate with diabetes, with the most common…”
Get full text

Gene Variants in the Novel Type 2 Diabetes Loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B Affect Different Aspects of Pancreatic β-Cell Function by Simonis-Bik, Annemarie M, Nijpels, Giel, van Haeften, Timon W, Houwing-Duistermaat, Jeanine J, Boomsma, Dorret I, Reiling, Erwin, van Hove, Els C, Diamant, Michaela, Kramer, Mark H H, Heine, Robert J, Maassen, J Antonie, Slagboom, P Eline, Willemsen, Gonneke, Dekker, Jacqueline M, Eekhoff, Elisabeth M, de Geus, Eco J, 't Hart, Leen M

“…Gene Variants in the Novel Type 2 Diabetes Loci CDC123/CAMK1D , THADA , ADAMTS9 , BCL11A , and MTNR1B Affect Different Aspects of Pancreatic β-Cell Function…”
Get full text

CD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice by Goudriaan, Jeltje R., Dahlmans, Vivian E.H., Teusink, Bas, Ouwens, D. Margriet, Febbraio, Maria, Maassen, J. Anton, Romijn, Johannes A., Havekes, Louis M., Voshol, Peter J.

“…CD36 (fatty acid translocase) is involved in high-affinity peripheral fatty acid uptake. Mice lacking CD36 exhibit increased plasma free fatty acid and…”
Get full text

Diabetes-associated mitochondrial DNA mutation A3243G impairs cellular metabolic pathways necessary for beta cell function by DE ANDRADE, P. B. M, RUBI, B, FRIGERIO, F, VAN DEN OUWELAND, J. M. W, MAASSEN, J. A, MAECHLER, P

“…Mitochondrial DNA (mtDNA) mutations cause several diseases, including mitochondrial inherited diabetes and deafness (MIDD), typically associated with the mtDNA…”
Get full text

Genistein directly inhibits GLUT4-mediated glucose uptake in 3T3-L1 adipocytes by Bazuine, Merlijn, van den Broek, Peter J.A., Maassen, J. Antonie

“…The isoflavone-derivative genistein is commonly applied as an inhibitor of tyrosine kinases. In this report we analyze the effect of genistein on…”
Get full text

Loss of 50% of excess weight using a very low energy diet improves insulin-stimulated glucose disposal and skeletal muscle insulin signalling in obese insulin-treated type 2 diabetic patients by Jazet, I. M, Schaart, G, Gastaldelli, A, Ferrannini, E, Hesselink, M. K, Schrauwen, P, Romijn, J. A, Maassen, J. A, Pijl, H, Ouwens, D. M, Meinders, A. E

“…Aims/hypothesis Both energy restriction (ER) per se and weight loss improve glucose metabolism in obese insulin-treated type 2 diabetic patients. Short-term ER…”
Get full text

Socio-ecological determinants of lifestyle behavior of women with overweight or obesity before, during and after pregnancy: qualitative interview analysis in the Netherlands by Timmermans, Y E G, van de Kant, K D G, Krumeich, J S M, Zimmermann, L J I, Dompeling, E, Kramer, B W, Maassen, L L J, Spaanderman, M A E, Vreugdenhil, A C E

“…Maternal overweight and obesity are related to several health risks in the periods before, during and after pregnancy including a higher risk of gestational…”
Get full text

Lentiviral Vectors Efficiently Transduce Quiescent Mature 3T3-L1 Adipocytes by Carlotti, Françoise, Bazuine, Merlijn, Kekarainen, Tuija, Seppen, Jurgen, Pognonec, Philippe, Maassen, J.Antonie, Hoeben, Rob C

“…Obesity is associated with many serious afflictions such as cardiovascular disease, cancer, and diabetes. One of the main cellular systems used to study the…”
Get full text

Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1 by Nascimento, Emmani B.M., Snel, Marieke, Guigas, Bruno, van der Zon, Gerard C.M., Kriek, Jan, Maassen, J. Antonie, Jazet, Ingrid M., Diamant, Michaela, Ouwens, D. Margriet

“…Type 2 diabetes is associated with alterations in protein kinase B (PKB/Akt) and mammalian target of rapamycin complex 1 (mTORC1) signalling. The proline-rich…”
Get full text

Forces applied to the maxillary incisors by video laryngoscopes and the Macintosh laryngoscope by LEE, R. A., VAN ZUNDERT, A. A. J., MAASSEN, R. L. J. G., WIERINGA, P. A.

“…Background Modern video laryngoscopes (VLSs) provide a superior view of the glottis, facilitating easier intubations. This study evaluates the forces applied…”
Get full text

Mitochondrial dysfunction in adipocytes: the culprit in type 2 diabetes by Maassen, J. A

Get full text

Proline-rich Akt substrate of 40-kDa contains a nuclear export signal by Wiza, Claudia, Nascimento, Emmani B.M., Linssen, Margot M.L., Carlotti, Françoise, Herzfeld de Wiza, Daniella, van der Zon, Gerard C.M., Maassen, J. Antonie, Diamant, Michaela, Guigas, Bruno, Ouwens, D. Margriet

“…The proline-rich Akt substrate of 40-kDa (PRAS40) has been linked to the regulation of the activity of the mammalian target of rapamycin complex 1 as well as…”
Get full text

RP105 deficiency aggravates vein graft disease and lesion instability via increased inflammation and mast cell activation by de Vries, M, Wezel, A, Maassen, J, Kip, P, Peters, H, Karper, J, Kuiper, J, Bot, I, Quax, P

Get full text