Search Results - "Maas, Roel J.M."

Macromolecular crowding creates heterogeneous environments of gene expression in picolitre droplets by Hansen, Maike M. K., Meijer, Lenny H. H., Spruijt, Evan, Maas, Roel J. M., Rosquelles, Marta Ventosa, Groen, Joost, Heus, Hans A., Huck, Wilhelm T. S.

“…Understanding the dynamics of complex enzymatic reactions in highly crowded small volumes is crucial for the development of synthetic minimal cells…”
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Expansion of the assembly of cowpea chlorotic mottle virus towards non-native and physiological conditions by Schoonen, Lise, Maas, Roel J.M., Nolte, Roeland J.M., van Hest, Jan C.M.

“…The cowpea chlorotic mottle virus (CCMV) is a nanoparticle that holds promise for diagnostic and therapeutic applications. The empty virus-like particle,…”
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A microfluidic optimal experimental design platform for forward design of cell-free genetic networks by van Sluijs, Bob, Maas, Roel J. M., van der Linden, Ardjan J., de Greef, Tom F. A., Huck, Wilhelm T. S.

“…Cell-free protein synthesis has been widely used as a “breadboard” for design of synthetic genetic networks. However, due to a severe lack of modularity,…”
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Transcription and Translation in Cytomimetic Protocells Perform Most Efficiently at Distinct Macromolecular Crowding Conditions by Vibhute, Mahesh A., Schaap, Mark H., Maas, Roel J. M., Nelissen, Frank H. T., Spruijt, Evan, Heus, Hans A., Hansen, Maike M. K., Huck, Wilhelm T. S.

“…The formation of cytomimetic protocells that capture the physicochemical aspects of living cells is an important goal in bottom-up synthetic biology. Here, we…”
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Protein Synthesis in Coupled and Uncoupled Cell-Free Prokaryotic Gene Expression Systems by Hansen, Maike M. K, Ventosa Rosquelles, Marta, Yelleswarapu, Maaruthy, Maas, Roel J. M, van Vugt-Jonker, Aafke J, Heus, Hans A, Huck, Wilhelm T. S

“…Secondary structure formation of mRNA, caused by desynchronization of transcription and translation, is known to impact gene expression in vivo. Yet,…”
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